Aligned electrospun polymer fibres for skeletal muscle regeneration [PDF]
Skeletal muscle repair is often overlooked in surgical procedures and in serious burn victims. Creating a tissue-engineered skeletal muscle would not only provide a grafting material for these clinical situations, but could also be used as a valuable ...
KJ Aviss, JE Gough, S Downes
doaj
Herculin, a Fourth Member of the MyoD Family of Myogenic Regulatory Genes [PDF]
We have identified and cloned herculin, a fourth mouse muscle regulatory gene. Comparison of its DNA and deduced amino acid sequences with those of the three known myogenic genes (MyoD, myogenin, and Myf-5) reveals scattered short spans with similarity ...
Miner, Jeffrey H., Wold, Barbara J.
core +1 more source
Muscle cell‐based biohybrid robot using nanomaterials for function enhancement and neural function for biomedical applications. Biohybrid robotics, an emerging field combining biological tissues with artificial systems, has made significant progress in developing various biohybrid constructs, including muscle‐cell‐driven biorobots and microbots.
Minkyu Shin +4 more
wiley +1 more source
Factors influencing in vivo transduction by recombinant adeno-associated viral vectors expressing the human factor IX cDNA. [PDF]
Long-term expression of coagulation factor IX (FIX) has been observed in murine and canine models following administration of recombinant adeno-associated viral (rAAV) vectors into either the portal vein or muscle. These studies were designed to evaluate
Davidoff, A +5 more
core +1 more source
Light‐Driven Quadrupedal Walking Biohybrid Robot With Antagonistic Muscle‐Rings and Inclined Joints
This work presents a light‐driven quadrupedal walking biohybrid robot powered by antagonistic muscle‐rings that achieve alternating walking gait. Optical training improved reproducibility of cultured muscle tissues, while caffeine treatment enhanced contractile force.
Shotaro Saito +5 more
wiley +1 more source
Interaction between mouse macrophages RAW264.7 and myoblasts C2C12 in a co-culture system
Objective To establish a co-culture system to observe the interactions between mouse macrophage RAW264.7 and myoblast C2C12 cells. Methods RAW264.7 and C2C12 cell lines were co-cultured in a Transwell chamber containing conditioned medium for myogenic ...
LUO We +5 more
doaj +1 more source
The Secretome From Mechanically Loaded Myoblasts Enhances Tenocyte-Mediated Wound Healing in a 3D In Vitro Tendon Model. [PDF]
Human primary myoblasts were subjected to 2% or 10% static mechanical loading for 24 h, with unloaded cells as controls. Conditioned media were collected and applied, together with normal medium, to a 3D tendon fibrin gel model. Secretome from loaded myoblasts, particularly 2% loading, enhanced tenocyte proliferation, scleraxis (SCX) expression, and ...
Li J +4 more
europepmc +2 more sources
LKB1 Destabilizes Microtubules in Myoblasts and Contributes to Myoblast Differentiation
Skeletal muscle myoblast differentiation and fusion into multinucleate myotubes is associated with dramatic cytoskeletal changes. We find that microtubules in differentiated myotubes are highly stabilized, but premature microtubule stabilization blocks differentiation.
Isma Mian +5 more
openaire +4 more sources
Normal myoblast fusion requires myoferlin [PDF]
Muscle growth occurs during embryonic development and continues in adult life as regeneration. During embryonic muscle growth and regeneration in mature muscle, singly nucleated myoblasts fuse to each other to form myotubes. In muscle growth, singly nucleated myoblasts can also fuse to existing large,syncytial myofibers as a mechanism of increasing ...
Katherine R, Doherty +7 more
openaire +2 more sources
A Poglut1 mutation causes a muscular dystrophy with reduced Notch signaling and satellite cell loss [PDF]
Skeletal muscle regeneration by muscle satellite cells is a physiological mechanism activated upon muscle damage and regulated by Notch signaling. In a family with autosomal recessive limbgirdle muscular dystrophy, we identified a missense mutation in ...
Cabrera Serrano, Macarena +5 more
core +1 more source

