Results 191 to 200 of about 100,863 (292)

2019 Canadian Cardiovascular Society/Canadian Association of Interventional Cardiology Guidelines on the Acute Management of ST-Elevation Myocardial Infarction: Focused Update on Regionalization and Reperfusion [PDF]

open access: bronze, 2019
Graham C. Wong   +33 more
openalex   +1 more source

Comparative Analysis of Pressure Drop (Δp): Hemodynamic Performance of Three Commercial Oxygenators During Cardiopulmonary Bypass

open access: yesArtificial Organs, EarlyView.
In this prospective study, a total of 60 patients were divided into three groups of 20 to compare the pressure drop (Δp) across three different oxygenators during cardiopulmonary bypass. The aim of this comparison was to enable evidence‐based optimization of the heart‐lung machine setup in order to minimize potential influencing factors and thereby ...
Jan Turra   +9 more
wiley   +1 more source

Outcomes in Patients Requiring VENO‐Venous Extracorporeal Membrane Oxygenation After Cardiac Surgery: An Analysis From the PELS‐1 Study

open access: yesArtificial Organs, EarlyView.
We report an insight from the PELS‐1– a multicentre, international registry focusing on postocardiotomy extracorporeal support use between 2000 and 2020. We focused on 24/2163 (1.1%) patients requiring V‐V ECMO after cardiac surgery. Mortality was high, with 21.7% of patients discharged alive and an overall 1‐year survival probability of 12.5 ...
Pasquale Nardelli   +39 more
wiley   +1 more source

Quercetin inhibits cardiomyocyte apoptosis via Sirt3/SOD2/mitochondrial reactive oxygen species during myocardial ischemia–reperfusion injury

open access: gold
Da Xiong   +9 more
openalex   +1 more source

Evaluation of a Rat Cardiopulmonary Bypass Model Using an Extraluminal Flow Oxygenator

open access: yesArtificial Organs, EarlyView.
A rat cardiopulmonary bypass model was constructed incorporating the developed extraluminal flow oxygenator and compared with a commercial intraluminal flow oxygenator. Both oxygenators demonstrated comparable gas exchange performance and inflammatory responses; however, the one developed in this study better preserved PLT counts.
Hirohito Sumikura   +3 more
wiley   +1 more source

Mitochondrial Ca2+ overload is a pivotal risk factor for lethal ventricular arrhythmias due to the oxidation of mitochondrial respirasome and energetic failure

open access: yesBritish Journal of Pharmacology, EarlyView.
The data that support the findings of this study are available from the corresponding author upon reasonable request. Some data may not be made available because of privacy or ethical restrictions. Background and Purpose Ventricular arrhythmias are a leading cause of death among patients with cardiovascular diseases and are associated with elevated ...
Felipe de Jesús Salazar‐Ramírez   +13 more
wiley   +1 more source

OPC-6535, an inhibitor of leukocyte activation, improves the left ventricular dysfunction in porcine myocardial Infarction model after long term reperfusion

open access: diamond, 1998
Goro Miyakoda   +6 more
openalex   +1 more source

Pharmacological inhibition of hydroxysteroid 11‐beta dehydrogenase type 1 (11‐βHSD1) after myocardial infarction preserves cardiac function in a translational mini‐pig model

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Plasma glucocorticoids increase acutely after MI, thereafter tissue levels are amplified selectively within cells expressing 11‐ßhydroxysteroid dehydrogenase type 1 (11‐ßHSD1) that regenerates active glucocorticoids from circulating metabolites.
Sara Al Disi   +19 more
wiley   +1 more source

The relationship between the cannabinoids and cardiac remodelling: A comprehensive review of pivotal mechanisms and emerging evidence

open access: yesBritish Journal of Pharmacology, EarlyView.
Cardiac remodelling and fibrosis after myocardial infarction or during chronic diseases, such as arterial and pulmonary hypertension or diabetes mellitus, continue to be the more important prognostic factors in determining survival, and so the search for effective anti‐fibrotic interventions is an important target for research and therapy in cardiology.
Anna Krzyżewska   +2 more
wiley   +1 more source

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