Abstract figure legend Mitochondrial SK channel enhancement reduces cardiac arrhythmia trigger. Spontaneous sarcoplasmic reticulum (SR) Ca2+ release via hyperactive RyR2s underlies an increased arrhythmia trigger, promoting early and delayed afterdepolarizations during stress. Hyperactive RyR2s causes rise in cytosolic [Ca2+] during diastole. Clearance
Dmitry Terentyev +7 more
wiley +1 more source
Evaluation of the effect of trans sodium crocetinate and crocetin on reperfusion injury in acute myocardial infarction with ST-segment elevation: A double-blind, randomized, placebo-controlled clinical trial. [PDF]
Elahabadi G +8 more
europepmc +1 more source
Circular RNAs: Unlocking new avenues in cardiometabolic disease management
Abstract figure legend In the heart circular RNAs (circRNAs) function as microRNA sponges, interact with proteins and can even undergo translation. Advances in bioinformatics now enable their identification through high‐throughput RNA sequencing, whereas computational analyses reveal differential expression in cardiac disease settings.
Kimberley M. Mellor +4 more
wiley +1 more source
Inhibition of TREM1 attenuates myocardial ischemia-reperfusion injury-induced cardiomyocyte pyroptosis by suppressing the activation of the NF-κB signaling pathway. [PDF]
Xu X +6 more
europepmc +1 more source
Cephalalgia—A “Tricky” Symptom for the Cardiologist: Acute Coronary Syndrome Presenting as Headache
ABSTRACT Rarely, headache may be the primary or sole symptom of acute myocardial ischemia; clinicians should recognize such atypical presentations and obtain an electrocardiogram and cardiac biomarkers to establish the diagnosis and guide urgent treatment.
Alexandros Vassiliades +8 more
wiley +1 more source
Protection against myocardial ischemia reperfusion injury by liquiritin: involvement of autophagy restoration targeting PIK3CA. [PDF]
Mao H, Li Z, Lu C.
europepmc +1 more source
Successful ECPR in Treating a Case of Chlorine Gas Poisoning Leading to ARDS and Cardiac Arrest
ABSTRACT Chlorine gas inhalation represents a rare but devastating toxicological emergency, capable of inducing fulminant acute respiratory distress syndrome (ARDS) and cardiovascular collapse. Extracorporeal cardiopulmonary resuscitation as a salvage therapy for a child who suffered refractory cardiac arrest following severe chlorine gas‐induced ARDS ...
Wu Ge +7 more
wiley +1 more source
Correction to "Failure to Protect Against Myocardial Ischemia-Reperfusion Injury With Sevoflurane Postcondioning in Old Rats In Vivo". [PDF]
europepmc +1 more source
The treatment of myocardial ischemia-reperfusion injury: potential roles of natural drug modulating CaMKII. [PDF]
Yang K +5 more
europepmc +1 more source
From Thrombolysis to Transplant: Navigating the Storm of Delayed STEMI and Cardiogenic Shock
ABSTRACT Delayed STEMI presentation can cause extensive myocardial necrosis, left ventricular thrombus, cardiogenic shock, and progression to end‐stage heart failure despite reperfusion. Early recognition and timely transfer to specialized shock centers are critical.
Syed Rafay Hussain Zaidi +8 more
wiley +1 more source

