Results 21 to 30 of about 100,863 (292)

Novel roles of κ-opioid receptor in myocardial ischemia-reperfusion injury [PDF]

PeerJ
Acute heart attack is the primary cause of cardiovascular-related death worldwide. A common treatment is reperfusion of ischemic tissue, which can cause irreversible damage to the myocardium.
Wen Zhang, Qi Zhang, Yali Liu, Jianming Pei, Na Feng   +4 more
doaj   +2 more sources

Calpain: the regulatory point of myocardial ischemia-reperfusion injury

Frontiers in Cardiovascular Medicine, 2023
Calpain is a conserved cysteine protease readily expressed in several mammalian tissues, which is usually activated by Ca2+ and with maximum activity at neutral pH.
Guo-Yang Liu, Guo-Yang Liu, Guo-Yang Liu, Wan-Li Xie, Wan-Li Xie, Wan-Li Xie, Yan-Ting Wang, Yan-Ting Wang, Yan-Ting Wang, Lu Chen, Lu Chen, Lu Chen, Zhen-Zhen Xu, Zhen-Zhen Xu, Zhen-Zhen Xu, Yong Lv, Yong Lv, Yong Lv, Qing-Ping Wu, Qing-Ping Wu, Qing-Ping Wu   +20 more
doaj   +1 more source

Relation between Initial QRS Duration with Myocardial Reperfusion after Primary PCI

Majalah Kardiologi Indonesia, 2013
Background.Reperfusion therapy in acute myocardial infarction aims at early and sustained reperfusion of the myocardium at risk. However, even when TIMI flow 3 is achieved, some patients have less optimal reperfusion at myocardial tissue level.
doaj   +1 more source

Loss of PI3Kα Mediates Protection From Myocardial Ischemia–Reperfusion Injury Linked to Preserved Mitochondrial Function

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Identifying new therapeutic targets for preventing the myocardial ischemia–reperfusion injury would have profound implications in cardiovascular medicine.
Pavel Zhabyeyev, Brent McLean, Wesam Bassiouni, Robert Valencia, Manish Paul, Ahmed M. Darwesh, John M. Seubert, Saugata Hazra, Gavin Y. Oudit   +8 more
doaj   +1 more source

ACUTE MYOCARDIAL INFARCTION: REPERFUSION TREATMENT [PDF]

Heart, 2002
The decision over whether to treat acute myocardial infarction (AMI) with a balloon or infusion of fibrinolytics remains controversial. During the past few years profound changes in both treatment modalities1–3, w1, w2 have substantially changed the arguments surrounding this longstanding debate.w3–5 The evidence shows that the alternative use of ...
RIBICHINI, Flavio Luciano, Wijns W.
openaire   +3 more sources

Optical Activation of the Dorsal Horn of the Thoracic Spinal Cord Prevents Ventricular Arrhythmias in Acute Myocardial Ischemia-Reperfusion Rats

Frontiers in Cardiovascular Medicine, 2022
Background and ObjectivesSpinal cord stimulation can prevent myocardial ischemia and reperfusion arrhythmias, but the relevant neurons and mechanisms remain unknown.
Yong Wu, Zhongxu Luo, Zhengtao Hu, Kun Lv, Yinhua Liu, Deguo Wang, Deguo Wang   +6 more
doaj   +1 more source

The role of gut microbiota in myocardial ischemia-reperfusion injury

Frontiers in Cardiovascular Medicine
Myocardial ischemia-reperfusion injury denotes the pathological damage resulting from the restoration of blood flow and oxygen supply following acute coronary artery occlusion.
Xin Chen, Xin Chen, Xin Chen, Lu Ye, Xin Zou, Yuan Zhou, Chan Peng, Rui Huang, Rui Huang, Rui Huang   +9 more
doaj   +1 more source

The Safety and Efficacy of Intravascular Lithotripsy in the Treatment of Severe Coronary Artery Calcification in 261 Cases: A Retrospective Study

Health Science Reports
Background Coronary artery calcification is strongly linked to factors such as advanced age, dyslipidemia, and chronic kidney disease. Severe coronary artery calcification significantly elevates the complexity and risk of percutaneous coronary ...
Tiankun Wu, Honghui Yang, Guian Xu, Qingman Li, Lijie Zhu, Yapan Yang, Tingjie Yang   +6 more
doaj   +1 more source

Non-coding RNAs modulate autophagy in myocardial ischemia-reperfusion injury: a systematic review

Journal of Cardiothoracic Surgery, 2021
The myocardial infarction is the main cause of morbidity and mortality in cardiovascular diseases around the world. Although the timely and complete reperfusion via Percutaneous Coronary Intervention (PCI) or thrombolysis have distinctly decreased the ...
Fuwen Huang, Jingting Mai, Jingwei Chen, Yinying He, Xiaojun Chen   +4 more
doaj   +1 more source

The temporal trends and short‐ and long‐term mortality of people with acute myocardial infarction and rheumatoid arthritis: a nationwide cohort study

Arthritis Care &Research, Accepted Article.
Aims We investigated whether a diagnosis of rheumatoid arthritis (RA) affects the quality of inpatient acute myocardial infarction (AMI) care and long‐term mortality post‐AMI. Methods We analysed data from 784,091 adults, 6,047 with a diagnosis of RA, from England and Wales hospitalised with AMI between 2005 and 2019 from the MINAP registry, linked ...
Megan Butler, Nicholas Weight, Muhammad Rashid, Rodrigo Bagur, Purvi Parwani, Samantha Hider, Edward Roddy, Robert Butler, Mamas A Mamas   +8 more
wiley   +1 more source