Results 121 to 130 of about 33,732 (260)

A new unique form of microRNA from human heart, microRNA-499c, promotes myofibril formation and rescues cardiac development in mutant axolotl embryos

open access: yesJournal of Biomedical Sciences, 2013
BackgroundA recessive mutation “c” in the Mexican axolotl, Ambystoma mexicanum, results in the failure of normal heart development. In homozygous recessive embryos, the hearts do not have organized myofibrils and fail to beat. In our previous studies, we
A. Kochegarov   +5 more
semanticscholar   +1 more source

EFFECT OF PROTEIN OXIDATION ON PARTICLE SIZE OF MYOFIBRILS [PDF]

open access: yes, 2016
In order to study the effect of protein oxidation on the structure of myofibrils, extracted myofibrils from porcine longissimus dorsi muscle were incubated with different concentrations of the oxidant NaClO (0, 5, 10, 20 and 40 mM) at 5 ºC for 16 h ...
Allegaert, Simon   +2 more
core  

Three distinct sarcomeric patterns of skeletal muscle revealed by SHG and TPEF microscopy.

open access: yes, 2009
International audienceWe have extensively characterized the sarcomeric SHG signal as a function of animal species (rat versus xenopus), age (adult versus larval) and tissue preparation (fixed or fresh) and we found that the main feature of this signal is
Bellanger, Jean-Jacques   +5 more
core   +3 more sources

Diffusion and physical constraints limit oxidative capacity, capillary supply and size of muscle fibres in mice and humans

open access: yesExperimental Physiology, EarlyView.
Abstract It has been suggested that angiogenesis during skeletal muscle fibre hypertrophy allows escape from the ‘size constraint’, which is the inverse relationship between oxidative capacity and muscle fibre cross‐sectional area (FCSA). It is, however, not known whether there are any limitations to the combinations of FCSA, oxidative capacity and ...
Hans Degens   +7 more
wiley   +1 more source

Impaired embryonic motility in dusp27 mutants reveals a developmental defect in myofibril structure

open access: yesDisease Models & Mechanisms, 2013
An essential step in muscle fiber maturation is the assembly of highly ordered myofibrils that are required for contraction. Much remains unknown about the molecular mechanisms governing the formation of the contractile apparatus.
Kandice C. Fero   +7 more
semanticscholar   +1 more source

Establishing laboratory standards for biological flight experiments [PDF]

open access: yes
The general objective of this research was to assess the effects of exposure to simulated microgravity on ultrastructural aspects of the contractile system in chicken skeletal muscle cells. This general objective had two specific experimental components:
Moriarity, Debra M., Young, Ronald B.
core   +1 more source

Sarcomere dynamics during muscular contraction and their implications to muscle function [PDF]

open access: yes, 2018
This article attempts to identify the key aspects of sarcomere inhomogeneity and the dynamics of sarcomere length changes in muscle contraction experiments and focuses on understanding the mechanics of myofibrils or muscle fibres when viewed as ...
Denoth, Jachen, Telley, Ivo
core  

Massive reduction of RyR1 in muscle spindles of mice carrying recessive Ryr1 mutations alters proprioception and causes scoliosis

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Intrafusal muscles contained within muscle spindles are endowed with ryanodie receptor 1 (RyR1) calcium channels and participate in proprioceptor function. Mutations in RyR1 linked to severe RYR1‐congenital myopathies affect calcium release from both extrafusal as well as intrafusal muscles.
Alexis Ruiz   +8 more
wiley   +1 more source

Modification of functional quality of raw myofibril preparation obtained from water-washed mechanically recovered chicken meat

open access: yesEuropean Food Research and Technology, 2013
The aim of this study was to evaluate the effect of enzymatic modification of poultry myofibril preparation on its selected functional properties, that is, solubility of proteins, polymerisation rates of myosin and actin, thermodynamic properties and ...
J. Stangierski, J. Zabielski, B. Grześ
semanticscholar   +1 more source

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