Results 11 to 20 of about 33,732 (260)

Alp/Enigma family proteins cooperate in Z-disc formation and myofibril assembly. [PDF]

PLoS Genetics, 2013
The Drosophila Alp/Enigma family protein Zasp52 localizes to myotendinous junctions and Z-discs. It is required for terminal muscle differentiation and muscle attachment.
Anja Katzemich, Kuo An Liao, Stefan Czerniecki, Frieder Schöck   +3 more
doaj   +2 more sources

Increased Hemodynamic Load in Early Embryonic Stages Alters Myofibril and Mitochondrial Organization in the Myocardium

Frontiers in Physiology, 2017
Normal blood flow is essential for proper heart formation during embryonic development, as abnormal hemodynamic load (blood pressure and shear stress) results in cardiac defects seen in congenital heart disease (CHD).
Madeline Midgett, Claudia S. López, Claudia S. López, Larry David, Alina Maloyan, Sandra Rugonyi   +5 more
doaj   +2 more sources

Cardiomyocyte Hypocontractility and Reduced Myofibril Density in End-Stage Pediatric Cardiomyopathy

Frontiers in Physiology, 2017
Dilated cardiomyopathy amongst children (pediatric cardiomyopathy, pediatric CM) is associated with a high morbidity and mortality. Because little is known about the pathophysiology of pediatric CM, treatment is largely based on adult heart failure ...
Ilse A. E. Bollen, Marijke van der Meulen, Kyra de Goede, Diederik W. D. Kuster, Michiel Dalinghaus, Jolanda van der Velden, Jolanda van der Velden   +6 more
doaj   +2 more sources

Effect of Sarcoplasmic Protein Solutions Dried at Different Times and Rates on Water Migration in Lamb Myofibril In Vitro [PDF]

Foods
To determine whether sarcoplasmic proteins affected water migration in myofibrils during air-drying, with protein denaturation as an indicator of sarcoplasmic protein changes, the extent of sarcoplasmic protein changes in lamb during air-drying was first
Weili Rao, Sijia Liu, Shiquan Kong, Zhenyu Wang, Zidan Shi, Jianming Cai   +5 more
doaj   +2 more sources

Fluvastatin-induced myofibrillar damage is associated with elevated ROS, and impaired fatty acid oxidation, and is preceded by mitochondrial morphological changes [PDF]

Scientific Reports
Previously, we showed that fluvastatin treatment induces myofibrillar damage and mitochondrial phenotypes in the skeletal muscles of Drosophila. However, the sequential occurrence of mitochondrial phenotypes and myofibril damage remains elusive.
Mohamed H. Al-Sabri, Nourhane Ammar, Stanislava Korzh, Ahmed M. Alsehli, Kimia Hosseini, Robert Fredriksson, Jessica Mwinyi, Michael J. Williams, Hadi Boukhatmi, Helgi B. Schiöth   +9 more
doaj   +2 more sources

The oxoglutarate dehydrogenase complex is involved in myofibril growth and Z-disc assembly in Drosophila

Journal of Cell Science, 2023
Myofibrils are long intracellular cables specific to muscles, composed mainly of actin and myosin filaments. The actin and myosin filaments are organized into repeated units called sarcomeres, which form the myofibrils.
Nicanor González-Morales, Océane Marescal, Szilárd Szikora, Anja Katzemich, T. Correia-Mesquita, P. Biró, M. Erdélyi, J. Mihály, F. Schöck   +8 more
semanticscholar   +1 more source

Skeletal Muscle in Cerebral Palsy: From Belly to Myofibril

Frontiers in Neurology, 2021
This review will provide a comprehensive, up-to-date review of the current knowledge regarding the pathophysiology of muscle contractures in cerebral palsy.
Jason J. Howard, W. Herzog
semanticscholar   +1 more source

The role of sarcomere length non-uniformities in residual force enhancement of skeletal muscle myofibrils [PDF]

Royal Society Open Science, 2016
The sarcomere length non-uniformity theory (SLNT) is a widely accepted explanation for residual force enhancement (RFE). RFE is the increase in steady-state isometric force following active muscle stretching. The SLNT predicts that active stretching of a
Kaleena Johnston, Azim Jinha, Walter Herzog   +2 more
doaj   +1 more source

The Hippo pathway controls myofibril assembly and muscle fiber growth by regulating sarcomeric gene expression

eLife, 2021
Skeletal muscles are composed of gigantic cells called muscle fibers, packed with force-producing myofibrils. During development, the size of individual muscle fibers must dramatically enlarge to match with skeletal growth.
Aynur Kaya-Çopur, Fabio Marchiano, Marco Y Hein, Daniel Alpern, Julie Russeil, Nuno Miguel Luis, Matthias Mann, Bart Deplancke, Bianca H Habermann, Frank Schnorrer   +9 more
doaj   +1 more source

Independent regulation of Z-lines and M-lines during sarcomere assembly in cardiac myocytes revealed by the automatic image analysis software sarcApp

eLife, 2023
Sarcomeres are the basic contractile units within cardiac myocytes, and the collective shortening of sarcomeres aligned along myofibrils generates the force driving the heartbeat.
Abigail C Neininger-Castro, James B Hayes, Zachary C Sanchez, Nilay Taneja, Aidan M Fenix, Satish Moparthi, Stéphane Vassilopoulos, Dylan Tyler Burnette   +7 more
doaj   +1 more source