Results 41 to 50 of about 33,732 (260)
The ubiquitin ligase Ozz decreases the replacement rate of embryonic myosin in myofibrils
Physiological Reports, 2021 Myosin, the most abundant myofibrillar protein in skeletal muscle, functions as a motor protein in muscle contraction. Myosin polymerizes into the thick filaments in the sarcomere where approximately 50% of embryonic myosin (Myh3) are replaced within 3 h
Emi Ichimura +5 more
doaj +1 more source
GSK3-β promotes calpain-1–mediated desmin filament depolymerization and myofibril loss in atrophy
Journal of Cell Biology, 2018 Myofibril breakdown is a fundamental cause of muscle wasting and inevitable sequel of aging and disease. We demonstrated that myofibril loss requires depolymerization of the desmin cytoskeleton, which is activated by phosphorylation. Here, we developed a
Dina Aweida +4 more
semanticscholar +1 more source
Antisense-mediated exon skipping: a therapeutic strategy for titin-based dilated cardiomyopathy [PDF]
, 2015 Frameshift mutations in the TTN gene encoding titin are a major cause for inherited forms of dilated cardiomyopathy (DCM), a heart disease characterized by ventricular dilatation, systolic dysfunction, and progressive heart failure. To date, there are no
Alessandra, Moretti +22 more
core +1 more source
SiR‐XActin: A Fluorescent Probe for Imaging Actin Dynamics in Live Cells
Angewandte Chemie, EarlyView.SiR‐XActin is a far‐red fluorescent probe for live‐cell imaging of actin that avoids genetic modification and minimizes disruption of actin dynamics, due to its lower binding affinity. Based on jasplakinolide‐like natural product hybrids and Si–Rhodamine, it offers photostable live‐cell no‐wash staining across cell types and microscopy techniques ...
Veselin Nasufovic +14 more
wiley +2 more sources
Frontiers in Physiology, 2019 IntroductionGene polymorphisms are associated with athletic phenotypes relying on maximal or continued power production and affect the specialization of skeletal muscle composition with endurance or strength training of untrained subjects.
Martin Flück +5 more
doaj +1 more source
Isolation of a new high molecular weight protein associated with desmin and vimentin filaments from avian embryonic skeletal muscle [PDF]
, 1982 Filaments with a diameter of 80-120 Å have been prepared from 14-d-old chick embryonic skeletal muscle, using a physiological salt solution and gel filtration chromatography.
Breckler, Jennifer, Lazarides, Elias
core +2 more sources
Foods, 2022 The shrinkage of the connective tissue and myofiber of lamb meat submitted to heat treatment or air drying at different storage stages (1, 5 and 7 days) was evaluated herein. The longitudinal and transverse shrinkage of heated lamb meat was significantly
Weili Rao +5 more
doaj +1 more source
Muscle fibrils: Solubilization and gel electrophoresis [PDF]
, 1971 In a three-year longitudinal intervention study developing an understanding of statisticalliteracy with a cohort of students from Years 4 to 6, teachers delivered lessons fromprovided materials, including scripts and prompts.
Callingham, R, English, L, Watson, J
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Journal of Physiological Sciences, 2023 This study was designed to probe the effect of chaperone-assisted selective autophagy (CASA) on the maintenance of proteostasis during exhaustive exercise and uncover the alteration of CASA in muscle fibers with pre-high-intensity interval training (HIIT)
Jiao Lu +8 more
doaj +1 more source
Magnetic susceptibility anisotropy of myocardium imaged by cardiovascular magnetic resonance reflects the anisotropy of myocardial filament α-helix polypeptide bonds. [PDF]
, 2015 BackgroundA key component of evaluating myocardial tissue function is the assessment of myofiber organization and structure. Studies suggest that striated muscle fibers are magnetically anisotropic, which, if measurable in the heart, may provide a tool ...
Dibb, Russell, Liu, Chunlei, Qi, Yi
core +1 more source