Results 121 to 130 of about 53,888 (279)

Downregulation of microRNA‐494 drives mitochondrial biogenesis and function in trained muscle

Experimental Physiology, EarlyView.
Abstract MicroRNAs (miRNAs) are key regulators of cellular processes, including mitochondrial function and energy metabolism. This study explores the regulation of miR‐494 in skeletal muscle and circulation, investigating its response to exercise training and an acute exercise bout, its association with metabolic disorders, and the effects of ...
Natália Pálešová, Klára Gabrišová, Jana Babulicová, Patrik Krumpolec, Zuzana Kovaničová, Tímea Kurdiová, Salvatore Modica, Christian Wolfrum, Jozef Ukropec, Barbara Ukropcová, Miroslav Baláž   +10 more
wiley   +1 more source

Exploring neuronal mechanisms of osteosarcopenia in older adults

The Journal of Physiology, EarlyView.
Abstract figure legend The mechanosensitive osteocytic network within the bone matrix acts as a receptor and plays a crucial role in the functional adaptation of bone to mechanical loading. Through mechanotransduction, osteocytes convert mechanical impulses into electrical signals, which are transmitted via afferent nerves to sympathetic preganglionic ...
Ilhan Karacan, Kemal Sıtkı Türker
wiley   +1 more source

Isolation, Culturing, and Differentiation of Primary Myoblasts from Skeletal Muscle of Adult Mice

Bio-Protocol, 2017
Myogenesis is a multi-step process that leads to the formation of skeletal muscle during embryonic development and repair of injured myofibers. In this process, myoblasts are the main effector cell type which fuse with each other or to injured myofibers ...
Lubna Hindi, Joseph McMillan, Dil Afroze, Sajedah Hindi, Ashok Kumar   +4 more
doaj   +1 more source

The repair capacity spectrum of human skeletal muscle injury from sports to surgical trauma settings

The Journal of Physiology, EarlyView.
Abstract figure legend The interplay between current knowledge, treatment strategies and remaining unsolved clinical challenges in optimising clinical outcomes for patients suffering skeletal muscle tissue injury. In particular the outcome for strain injuries and acute extremity compartment syndrome remains poor, despite extensive work in animal models.
Grith Højfeldt, Christian Hoegsbjerg, Arvind G. von Keudell, Abigail L. Mackey   +3 more
wiley   +1 more source

Modular co-option of cardiopharyngeal genes during non-embryonic myogenesis

EvoDevo, 2019
Background In chordates, cardiac and body muscles arise from different embryonic origins. In addition, myogenesis can be triggered in adult organisms, during asexual development or regeneration.
Maria Mandela Prünster, Lorenzo Ricci, Federico D. Brown, Stefano Tiozzo   +3 more
doaj   +1 more source

Muscle regeneration is improved by hot water immersion but unchanged by cold following a simulated musculoskeletal injury in humans

The Journal of Physiology, EarlyView.
Abstract figure legend Thirty‐four participants underwent muscle damage (electrically stimulated eccentric contractions) triggering regenerative processes following myofiber necrosis. Participants were treated for 10 days cold (CWI) (15 min, 12{degree sign}C), thermoneutral (TWI) (30 min, 32{degree sign}C) or hot (HWI) (60 min, 42{degree sign}C) water ...
Valentin Dablainville, Adèle Mornas, Tom Normand‐Gravier, Maha Al‐Mulla, Emmanouil Papakostas, Bruno Olory, Theodorakys Marin Fermin, Frantzeska Zampeli, Nelda Nader, Marine Alhammoud, Freya Bayne, Anthony M. J. Sanchez, Marco Cardinale, Robin Candau, Henri Bernardi, Sébastien Racinais   +15 more
wiley   +1 more source

AN ANALYSIS OF MYOGENESIS BY THE USE OF FLUORESCENT ANTIMYOSIN [PDF]

, 1957
Howard Holtzer, John M. Marshall, Henry Finck   +2 more
openalex   +1 more source

MiR‐1 Is Regulated by Hydrogen Peroxide via MAPK and Limits Cell Migration and Invasion

Environmental Toxicology, Volume 40, Issue 11, Page 1249-1260, November 2025.
ABSTRACT MicroRNA‐1 (miR‐1) is a conserved microRNA that is highly expressed in skeletal and cardiac muscle tissues. Moreover, miR‐1 regulates genes and has critical roles in cell migration and invasion. Downregulation of miR‐1 has been found in many pathologies of numerous organs, including the lungs.
Maricica Pacurari, Irmanecia Cox, Ibrahim Farah   +2 more
wiley   +1 more source

Retinoic Acid Inhibition Alters Intestinal Composition in Zebrafish: A Non‐genetic Model to Study Hirschsprung Disease?

Neurogastroenterology &Motility, Volume 37, Issue 11, November 2025.
This study investigates the role of retinoic acid (RA) in intestinal development using the zebrafish. RA inhibition reduced enteric neurons and altered non‐neuronal cell populations. Compared to the ret mutant model, RA deficiency caused distinct shifts in epithelial, immune, and mesenchymal populations, highlighting RA's broader influence on ...
Naomi J. M. Kakiailatu, Wei Zhang, Laura E. Kuil, Eric Bindels, Joke T. M. Zink, Michael Vermeulen, Emma de Pater, Veerle Melotte, Maria M. Alves   +8 more
wiley   +1 more source

Simulated microgravity attenuates myogenesis and contractile function of 3D engineered skeletal muscle tissues

npj Microgravity
While the effects of microgravity on inducing skeletal muscle atrophy have been extensively studied, the impacts of microgravity on myogenesis and its mechanisms remain unclear. In this study, we developed a microphysiological system of engineered muscle
Zhanping Ren, Eun Hyun Ahn, Minjae Do, Devin B. Mair, Amir Monemianesfahani, Peter H. U. Lee, Deok-Ho Kim   +6 more
doaj   +1 more source