Results 11 to 20 of about 64,746 (288)

Arsenic Inhibits Myogenic Differentiation and Muscle Regeneration

Environmental Health Perspectives, 2010
The incidence of low birth weights is increased in offspring of women who are exposed to high concentrations of arsenic in drinking water compared with other women. We hypothesized that effects of arsenic on birth weight may be related to effects on myogenic differentiation.We investigated the effects of arsenic trioxide (As2O3) on the myogenic ...
Yen, Yuan-Peng, Tsai, Keh-Sung, Chen, Ya-Wen, Huang, Chun-Fa, Yang, Rong-Sen, Liu, Shing-Hwa   +5 more
openaire   +4 more sources

Stimulation of Non-canonical NF-κB Through Lymphotoxin-β-Receptor Impairs Myogenic Differentiation and Regeneration of Skeletal Muscle

Frontiers in Cell and Developmental Biology, 2021
Myogenic differentiation, muscle stem cell functionality, and regeneration of skeletal muscle are cellular processes under tight control of various signaling pathways.
Manuel Schmidt, Anja Weidemann, Christine Poser, Anne Bigot, Julia von Maltzahn   +4 more
doaj   +1 more source

Modeling Stem Cell Myogenic Differentiation [PDF]

Scientific Reports, 2017
AbstractThe process of stem cell myogenesis (transformation into skeletal muscle cells) includes several stages characterized by the expression of certain combinations of myogenic factors. The first part of this process is accompanied by cell division, while the second part is mainly associated with direct differentiation. The mechanical cues are known
Rajiv S. Deshpande, Alexander A. Spector
openaire   +2 more sources

Confined Sandwichlike Microenvironments Tune Myogenic Differentiation [PDF]

ACS Biomaterials Science & Engineering, 2017
Sandwichlike (SW) cultures are engineered as a multilayer technology to simultaneously stimulate dorsal and ventral cell receptors, seeking to mimic cell adhesion in three-dimensional (3D) environments in a reductionist manner. The effect of this environment on cell differentiation was investigated for several cell types cultured in standard growth ...
Ballester-Beltrán, José, Trujillo, Sara, Alakpa, Enateri V, Compañ, Vicente, Gavara, Rafael, Meek, Dominic, West, Christopher C, Péault, Bruno, Dalby, Matthew J, Salmerón-Sánchez, Manuel   +9 more
openaire   +7 more sources

Reductive stress impairs myogenic differentiation

Redox Biology, 2020
Myo-satellite cells regenerate and differentiate into skeletal muscle (SM) after acute or chronic injury. Changes in the redox milieu towards the oxidative arm at the wound site are known to compromise SM regeneration. Recently, we reported that abrogation of Nrf2/antioxidant signaling promotes oxidative stress and impairs SM regeneration in C57/Bl6 ...
Namakkal S. Rajasekaran, Sandeep Balu Shelar, Dean P. Jones, John R. Hoidal   +3 more
openaire   +3 more sources

mTORCing about myogenic differentiation [PDF]

Cell Cycle, 2014
The C2C12 myoblast cell line has been extensively studied as it has the potential to differentiate from serum-starved confluent monolayer cultures into myotubes, (Fig. 1, upper panel) which can further align and form muscle fibers. Furthermore, C2C12 myoblasts can differentiate into adipose and bone-type lineages, depending on the conditions present ...
Iadevaia, V, Cowan, JL, Coldwell, MJ
openaire   +2 more sources

Sprouty2 mediated tuning of signalling is essential for somite myogenesis [PDF]

, 2015
Background: Negative regulators of signal transduction cascades play critical roles in controlling different aspects of normal embryonic development.
A Borycki, A Faedo, A Sasaki, AA Mailleux, AC Rios, Andrea Münsterberg, B Christ, B Hausott, C de Alvaro, C Marcelle, C Zhang, CC Lee, D Chambers, D Sayed, D Sweetman, D Sweetman, G Christofori, G Minowada, GF Mok, Grant Wheeler, H Hanafusa, HJ Kim, HM Poppleton, I Laziz, JD Tefft, JM Mason, JM Mason, K Matsumura, K Shim, Katarzyna Goljanek Whysall, L Cheng, L Chi, L Chi, LE Alvares, M Abu-Elmagd, M Buckingham, M Ishida, M Schmidt, M Schmidt, MA Basson, MA Cabrita, MC Eblaghie, MJ Frank, Muhammad Abu-Elmagd, N Hacohen, OD Klein, P Li, PA Branney, S Eloy-Trinquet, TG Smith, V Hamburger, Y Yigzaw   +51 more
core   +13 more sources

Notch signaling leads to a slower progression of embryonic myogenic differentiation in Landrace than in Langtang pigs

Acta Biochimica et Biophysica Sinica, 2022
Delving into porcine embryonic myogenesis is the key to elucidate the complex regulation of breed-specific differences in growth performance and meat production.
Cai Shufang, Hu Bin, Zhu Qi, Duo Tianqi, Wang Xiaoyu, Tong Xian, Luo Xiaorong, Yuan Renqiang, Chen Yaosheng, Wang Jing, Luo Chenglong, Xing Baosong, Mo Delin   +12 more
doaj   +1 more source

Factors influencing myogenic differentiation of adipose-derived stem cells and their application in muscle regeneration

Chinese Journal of Plastic and Reconstructive Surgery, 2022
Skeletal muscle regeneration mainly depends on muscle satellite cells; however, these cells are not sufficient for supporting repair and regeneration in volumetric muscle loss (VML), Duchenne muscular dystrophy, and other muscle injuries or muscle ...
Na Liu, Guanhuier Wang, Yonghuan Zhen, Yujia Shang, Fangfei Nie, Lingjuan Zhu, Zhenmin Zhao, Yang An   +7 more
doaj   +1 more source

Ryanodine receptor RyR1-mediated elevation of Ca2+ concentration is required for the late stage of myogenic differentiation and fusion

Journal of Animal Science and Biotechnology, 2022
Background Cytosolic Ca2+ plays vital roles in myogenesis and muscle development. As a major Ca2+ release channel of endoplasmic reticulum (ER), ryanodine receptor 1 (RyR1) key mutations are main causes of severe congenital myopathies.
Kai Qiu, Yubo Wang, Doudou Xu, Linjuan He, Xin Zhang, Enfa Yan, Lu Wang, Jingdong Yin   +7 more
doaj   +1 more source