Kindlin 2 regulates myogenic related factor myogenin via a canonical Wnt signaling in myogenic differentiation. [PDF]
PLoS ONE, 2013 Kindlin 2, as an integrin-associated protein, is required for myocyte elongation and fusion. However, the association of Kindlin 2 with muscle differentiation-related signaling pathways is unknown. Here, we identified a mechanism that Kindlin 2 regulates
Yu Yu +5 more
doaj +1 more source
Cells, 2022 Myostatin (MSTN) is a negative regulator of skeletal muscle development and plays an important role in muscle development. Fluctuations in gene expression influenced by DNA methylation are critical for homeostatic responses in muscle.
Yiping Zhao +8 more
doaj +1 more source
Apol9a regulates myogenic differentiation via the ERK1/2 pathway in C2C12 cells
Frontiers in Pharmacology, 2022 Background: The rising prevalence of obesity and its complications is a big challenge for the global public health. Obesity is accompanied by biological dysfunction of skeletal muscle and the development of muscle atrophy.
Xuan Jiang +11 more
doaj +1 more source
MicroRNA-222 regulates muscle alternative splicing through Rbm24 during differentiation of skeletal muscle cells [PDF]
, 2016 A number of microRNAs have been shown to regulate skeletal muscle development and differentiation. MicroRNA-222 is downregulated during myogenic differentiation and its overexpression leads to alteration of muscle differentiation process and specialized ...
Cappella, Marisa +7 more
core +2 more sources
The Stat3-Fam3a axis promotes muscle stem cell myogenic lineage progression by inducing mitochondrial respiration. [PDF]
, 2019 Metabolic reprogramming is an active regulator of stem cell fate choices, and successful stem cell differentiation in different compartments requires the induction of oxidative phosphorylation.
Cunningham, Thomas J +9 more
core +3 more sources
JAK-STAT pathway and myogenic differentiation [PDF]
JAK-STAT, 2013 Myogenic differentiation plays an important role in muscle regeneration and is regulated by two transcription factor families, MRFs and MEF2, which induce differentiation of myoblasts through expression of the muscle-specific gene, myogenin. In addition, many intracellular signaling pathways are also involved in myogenic differentiation, including p38 ...
Jang, You-Na, Baik, Eun Joo
openaire +2 more sources
Animals, 2022 Poultry plays an important role in the meat consumer market and is significant to further understanding the potential mechanism of muscle development in the broiler.
Zhen Zhou +7 more
doaj +1 more source
The occipital lateral plate mesoderm is a novel source for vertebrate neck musculature [PDF]
, 2010 In vertebrates, body musculature originates from somites, whereas head muscles originate from the cranial mesoderm. Neck muscles are located in the transition between these regions.
Christ, B. +9 more
core +1 more source
Directing Myogenic Mesenchymal Stem Cell Differentiation [PDF]
Circulation Research, 2008 See related article, pages 635–642 Vascular smooth muscle cells (SMCs) play an important role in the embryonic and postnatal development and remodeling of blood vessels. In mature vasculature, SMCs regulate the vascular tone and, thereby, the blood pressure and blood distribution.
Peter E, Westerweel, Marianne C, Verhaar
openaire +2 more sources
DNMT3B in vitro knocking-down is able to reverse embryonal rhabdomyosarcoma cell phenotype through inhibition of proliferation and induction of myogenic differentiation [PDF]
, 2016 Aberrant DNA methylation has been frequently observed in many human cancers, including rhabdomyosarcoma (RMS), the most common soft tissue sarcoma in children.
Camero, Simona +11 more
core +1 more source