Results 31 to 40 of about 64,746 (288)
RIP2, a Checkpoint in Myogenic Differentiation [PDF]
Molecular and Cellular Biology, 2002 Using a subtractive cDNA library hybridization approach, we found that receptor interacting protein 2 (RIP2), a tumor necrosis factor receptor 1 (TNFR-1)-associated factor, is a novel early-acting gene that decreases markedly in expression during myogenic differentiation.
Barbara, Munz +3 more
openaire +2 more sources
Involvement of cdks and cyclins in muscle differentiation
European Journal of Histochemistry, 2009 Myocyte differentiation is due to transcription of genes that characterize the phenotypic and biochemical identity of differentiated muscle cells. These are the myogenic regulatory factors (MRFs) MyoD, Myf5, myogenin and MRF4.
M De Falco, A De Luca
doaj +1 more source
FTO-mediated demethylation of GADD45B promotes myogenesis through the activation of p38 MAPK pathway
Molecular Therapy: Nucleic Acids, 2021 N6-methyladenosine (m6A) modification plays a critical role in mammalian development. However, the role of m6A in the skeletal muscle development remains largely unknown.
Kaiping Deng +10 more
doaj +1 more source
Myogenic Cell Proliferation and Differentiation
Poultry Science, 1991 It is generally thought that growth factors play a major role in regulating proliferation and differentiation of myogenic cells. Cell culture studies indicate that of the known growth factors, the fibroblast growth factors, the transforming growth factor beta, and the insulin-like growth factor families play the most significant roles in this process ...
W R, Dayton, M R, Hathaway
openaire +2 more sources
PLoS ONE, 2012 p38 mitogen-activated protein kinase (MAPK) is an essential kinase involved in myogenic differentiation. Although many substrates of p38 MAPK have been identified, little is known about its upstream activators during myogenic differentiation.
Fang Xiao +4 more
doaj +1 more source
New insights into the epigenetic control of satellite cells [PDF]
, 2015 Epigenetics finely tunes gene expression at a functional level without modifying the DNA sequence, thereby contributing to the complexity of genomic regulation.
Adamo, Sergio +2 more
core +1 more source
An initial blueprint for myogenic differentiation [PDF]
Genes & Development, 2005 We have combined genome-wide transcription factor binding and expression profiling to assemble a regulatory network controlling the myogenic differentiation program in mammalian cells. We identified a cadre of overlapping and distinct targets of the key myogenic regulatory factors (MRFs)—MyoD and myogenin—and Myocyte Enhancer Factor 2 (MEF2).
Alexandre, Blais +5 more
openaire +2 more sources
Gene amplification during myogenic differentiation
Oncotarget, 2016 Gene amplifications are mostly an attribute of tumor cells and drug resistant cells. Recently, we provided evidence for gene amplifications during differentiation of human and mouse neural progenitor cells. Here, we report gene amplifications in differentiating mouse myoblasts (C2C12 cells) covering a period of 7 days including pre-fusion, fusion and ...
Fischer, Ulrike +4 more
openaire +3 more sources
Myogenic and melanotic differentiated medulloblastoma: case report [PDF]
Turkish Neurosurgery, 2010 Medulloblastoma is the most common malignant tumor of childhood and usually arises from the cerebellar vermis. Several histological types of medulloblastoma have been described. Myogenic and melanotic differentiated medulloblastoma are seldom seen. We present a case diagnosed as myogenic medulloblastoma with focal areas of melanotic differentiation.
Kurt, Gokhan +4 more
openaire +3 more sources
Mechanisms of action of hESC-secreted proteins that enhance human and mouse myogenesis. [PDF]
, 2014 Adult stem cells grow poorly in vitro compared to embryonic stem cells, and in vivo stem cell maintenance and proliferation by tissue niches progressively deteriorates with age.
CONBOY, Irina M +6 more
core +3 more sources