Results 31 to 40 of about 41,288 (271)
Involvement of cdks and cyclins in muscle differentiation
Myocyte differentiation is due to transcription of genes that characterize the phenotypic and biochemical identity of differentiated muscle cells. These are the myogenic regulatory factors (MRFs) MyoD, Myf5, myogenin and MRF4.
M De Falco, A De Luca
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FTO-mediated demethylation of GADD45B promotes myogenesis through the activation of p38 MAPK pathway
N6-methyladenosine (m6A) modification plays a critical role in mammalian development. However, the role of m6A in the skeletal muscle development remains largely unknown.
Kaiping Deng +10 more
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Modeling Stem Cell Myogenic Differentiation [PDF]
AbstractThe process of stem cell myogenesis (transformation into skeletal muscle cells) includes several stages characterized by the expression of certain combinations of myogenic factors. The first part of this process is accompanied by cell division, while the second part is mainly associated with direct differentiation. The mechanical cues are known
Rajiv S. Deshpande, Alexander A. Spector
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Poultry plays an important role in the meat consumer market and is significant to further understanding the potential mechanism of muscle development in the broiler.
Zhen Zhou +7 more
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Convergence of Igf2 expression and adhesion signalling via RhoA and p38 MAPK enhances myogenic differentiation [PDF]
Cell-cell contact is essential for appropriate co-ordination of development and it initiates significant signalling events. During myogenesis, committed myoblasts migrate to sites of muscle formation, align and form adhesive contacts that instigate cell ...
Cobb, L.J. +8 more
core +1 more source
Adult skeletal muscle regeneration relies on the activity of satellite cells residing in the skeletal muscle niche. However, systemic and intrinsic factors decrease the myogenic differentiation potential of satellite cells thereby impairing muscle ...
Aref Shahini +5 more
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Myogenic Cell Proliferation and Differentiation
It is generally thought that growth factors play a major role in regulating proliferation and differentiation of myogenic cells. Cell culture studies indicate that of the known growth factors, the fibroblast growth factors, the transforming growth factor beta, and the insulin-like growth factor families play the most significant roles in this process ...
W R, Dayton, M R, Hathaway
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PFN1 Inhibits Myogenesis of Bovine Myoblast Cells via Cdc42-PAK/JNK
Myoblast differentiation is essential for the formation of skeletal muscle myofibers. Profilin1 (Pfn1) has been identified as an actin-associated protein, and has been shown to be critically important to cellular function.
Jingjing Zi +10 more
doaj +1 more source
Bit1 is an essential regulator of myogenic differentiation [PDF]
Muscle differentiation requires a complex signaling cascade that leads to multinucleated myofibers. Genes regulating the intrinsic mitochondrial apoptotic pathway also function in controlling cell differentiation. How such signaling pathways are regulated during differentiation is not fully understood.
Genevieve S, Griffiths +8 more
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Commitment during stenotele differentiation in Hydra is localized near the S/G2 boundary in the terminal cell cycle [PDF]
The timing of commitment during stenotele differentiation in Hydra was determined. Regeneration of isolated distal regions of the body column induces stenotele differentiation.
Charles +4 more
core +1 more source

