Results 41 to 50 of about 41,288 (271)
Reductive stress impairs myogenic differentiation
Redox Biology, 2020 Myo-satellite cells regenerate and differentiate into skeletal muscle (SM) after acute or chronic injury. Changes in the redox milieu towards the oxidative arm at the wound site are known to compromise SM regeneration. Recently, we reported that abrogation of Nrf2/antioxidant signaling promotes oxidative stress and impairs SM regeneration in C57/Bl6 ...
Namakkal S. Rajasekaran +3 more
openaire +3 more sources
Myogenic and melanotic differentiated medulloblastoma: case report [PDF]
Turkish Neurosurgery, 2010 Medulloblastoma is the most common malignant tumor of childhood and usually arises from the cerebellar vermis. Several histological types of medulloblastoma have been described. Myogenic and melanotic differentiated medulloblastoma are seldom seen. We present a case diagnosed as myogenic medulloblastoma with focal areas of melanotic differentiation.
Kurt, Gokhan +4 more
openaire +3 more sources
Obesity Impairs Embryonic Myogenesis by Enhancing BMP Signaling within the Dermomyotome
Advanced Science, 2021 Obesity during pregnancy leads to adverse health outcomes in offspring. However, the initial effects of maternal obesity (MO) on embryonic organogenesis have yet to be thoroughly examined.
Liang Zhao +8 more
doaj +1 more source
Cells, 2023 Skeletal myogenesis is an intricate process involving the differentiation of progenitor cells into myofibers, which is regulated by actin cytoskeletal dynamics and myogenic transcription factors.
Mai Thi Nguyen +3 more
doaj +1 more source
Physiological Reports, 2023 TRPM8 agonist has been reported to promote osteogenic differentiation of mesenchymal stem cells (MSCs), therefore we evaluated whether cooling‐induced activation of TRPM8 promotes myogenic differentiation of MSCs.
Ryo Takagi +5 more
doaj +1 more source
Cells, 2022 Muscle injuries, degenerative diseases and other lesions negatively affect functioning of human skeletomuscular system and thus quality of life. Therefore, the investigation of molecular mechanisms, stimulating myogenic differentiation of primary ...
Rokas Mikšiūnas +2 more
doaj +1 more source
, 2009 Pax3 and Pax7 are paired-box transcription factors with roles in developmental and adult regenerative myogenesis. Pax3 and Pax7 are expressed by postnatal satellite cells or their progeny but are down regulated during myogenic differentiation.
Morgan, JE +25 more
core +1 more source
Novel TAZ modulators enhance myogenic differentiation and muscle regeneration
, 2021 Background and Purpose The transcriptional co-activator with PDZ-binding motif (TAZ) is a key controller of mesenchymal stem cell differentiation through its nuclear localization and subsequent interaction with master transcription factors. In particular,
황은숙
core +1 more source
BRD3 and BRD4 BET Bromodomain Proteins Differentially Regulate Skeletal Myogenesis
Scientific Reports, 2017 Myogenic differentiation proceeds through a highly coordinated cascade of gene activation that necessitates epigenomic changes in chromatin structure.
Thomas C. Roberts +7 more
doaj +1 more source
Inhibition of glycogen synthase kinase-3β attenuates glucocorticoid-induced suppression of myogenic differentiation in vitro. [PDF]
PLoS ONE, 2014 Glucocorticoids are the only therapy that has been demonstrated to alter the progress of Duchenne muscular dystrophy (DMD), the most common muscular dystrophy in children.
Zhenyu Ma +4 more
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