Results 41 to 50 of about 64,746 (288)
PFN1 Inhibits Myogenesis of Bovine Myoblast Cells via Cdc42-PAK/JNK
Cells, 2022 Myoblast differentiation is essential for the formation of skeletal muscle myofibers. Profilin1 (Pfn1) has been identified as an actin-associated protein, and has been shown to be critically important to cellular function.
Jingjing Zi +10 more
doaj +1 more source
Smad7:β-catenin Complex Regulates Myogenic Gene Transcription [PDF]
, 2019 Recent reports indicate that Smad7 promotes skeletal muscle differentiation and growth. We previously documented a non-canonical role of nuclear Smad7 during myogenesis, independent of its role in TGF-β signaling.
McDermott, John +2 more
core +1 more source
Stem Cell Research, 2018 Adult skeletal muscle regeneration relies on the activity of satellite cells residing in the skeletal muscle niche. However, systemic and intrinsic factors decrease the myogenic differentiation potential of satellite cells thereby impairing muscle ...
Aref Shahini +5 more
doaj +1 more source
The action of obestatin in skeletal muscle repair: stem cell expansion, muscle growth, and microenvironment remodeling [PDF]
, 2015 The development of therapeutic strategies for skeletal muscle diseases, such as physical injuries and myopathies, depends on the knowledge of regulatory signals that control the myogenic process. The obestatin/GPR39 system operates as an autocrine signal
ADAMO, Sergio +16 more
core +1 more source
The emergence of Pax7-expressing muscle stem cells during vertebrate head muscle development [PDF]
, 2015 Pax7 expressing muscle stem cells accompany all skeletal muscles in the body and in healthy individuals, efficiently repair muscle after injury. Currently, the in vitro manipulation and culture of these cells is still in its infancy, yet muscle stem ...
Anna eNoble +9 more
core +2 more sources
Obesity Impairs Embryonic Myogenesis by Enhancing BMP Signaling within the Dermomyotome
Advanced Science, 2021 Obesity during pregnancy leads to adverse health outcomes in offspring. However, the initial effects of maternal obesity (MO) on embryonic organogenesis have yet to be thoroughly examined.
Liang Zhao +8 more
doaj +1 more source
Scientific Reports, 2017 Myogenic differentiation results in different cell type cooperation, but the molecules involved in the myogenic cell activation remain elusive. Here, we show that muscle-resident pre-adipocytes promote myogenic differentiation through the secretion of ...
Thierry Rouaud +6 more
doaj +1 more source
Cells, 2023 Skeletal myogenesis is an intricate process involving the differentiation of progenitor cells into myofibers, which is regulated by actin cytoskeletal dynamics and myogenic transcription factors.
Mai Thi Nguyen +3 more
doaj +1 more source
Physiological Reports, 2023 TRPM8 agonist has been reported to promote osteogenic differentiation of mesenchymal stem cells (MSCs), therefore we evaluated whether cooling‐induced activation of TRPM8 promotes myogenic differentiation of MSCs.
Ryo Takagi +5 more
doaj +1 more source
Role of MiR-325-3p in the Regulation of CFL2 and Myogenic Differentiation of C2C12 Myoblasts
Cells, 2021 Skeletal myogenesis is required to maintain muscle mass and integrity, and impaired myogenesis is causally linked to the etiology of muscle wasting. Recently, it was shown that excessive uptake of saturated fatty acids (SFA) plays a significant role in ...
Mai Thi Nguyen, Wan Lee
doaj +1 more source