Results 41 to 50 of about 814,354 (242)
Reductive stress impairs myogenic differentiation
Redox Biology, 2020 Myo-satellite cells regenerate and differentiate into skeletal muscle (SM) after acute or chronic injury. Changes in the redox milieu towards the oxidative arm at the wound site are known to compromise SM regeneration. Recently, we reported that abrogation of Nrf2/antioxidant signaling promotes oxidative stress and impairs SM regeneration in C57/Bl6 ...
Namakkal S. Rajasekaran +3 more
openaire +3 more sources
Cells, 2023 Skeletal myogenesis is an intricate process involving the differentiation of progenitor cells into myofibers, which is regulated by actin cytoskeletal dynamics and myogenic transcription factors.
Mai Thi Nguyen +3 more
doaj +1 more source
Physiological Reports, 2023 TRPM8 agonist has been reported to promote osteogenic differentiation of mesenchymal stem cells (MSCs), therefore we evaluated whether cooling‐induced activation of TRPM8 promotes myogenic differentiation of MSCs.
Ryo Takagi +5 more
doaj +1 more source
BRD3 and BRD4 BET Bromodomain Proteins Differentially Regulate Skeletal Myogenesis
Scientific Reports, 2017 Myogenic differentiation proceeds through a highly coordinated cascade of gene activation that necessitates epigenomic changes in chromatin structure.
Thomas C. Roberts +7 more
doaj +1 more source
Role of MiR-325-3p in the Regulation of CFL2 and Myogenic Differentiation of C2C12 Myoblasts
Cells, 2021 Skeletal myogenesis is required to maintain muscle mass and integrity, and impaired myogenesis is causally linked to the etiology of muscle wasting. Recently, it was shown that excessive uptake of saturated fatty acids (SFA) plays a significant role in ...
Mai Thi Nguyen, Wan Lee
doaj +1 more source
Commitment during stenotele differentiation in Hydra is localized near the S/G2 boundary in the terminal cell cycle [PDF]
, 1982 The timing of commitment during stenotele differentiation in Hydra was determined. Regeneration of isolated distal regions of the body column induces stenotele differentiation.
Charles +4 more
core +1 more source
FEBS Open Bio, 2020 Thioredoxin (Trx) is a hydrogen acceptor of ribonucleotide reductase and a regulator of some enzymes and receptors. It has been previously shown that significantly elevated levels of Trx expression are associated with the osteogenic differentiation of ...
Meiling Liu +9 more
doaj +1 more source
Cells, 2022 Muscle injuries, degenerative diseases and other lesions negatively affect functioning of human skeletomuscular system and thus quality of life. Therefore, the investigation of molecular mechanisms, stimulating myogenic differentiation of primary ...
Rokas Mikšiūnas +2 more
doaj +1 more source
Inhibition of glycogen synthase kinase-3β attenuates glucocorticoid-induced suppression of myogenic differentiation in vitro. [PDF]
PLoS ONE, 2014 Glucocorticoids are the only therapy that has been demonstrated to alter the progress of Duchenne muscular dystrophy (DMD), the most common muscular dystrophy in children.
Zhenyu Ma +4 more
doaj +1 more source
iScienceSummary: Skeletal muscle development and regeneration requires the activities of myogenic and non-myogenic muscle stem cell populations. Non-myogenic muscle stem cells, such as fibro-adipogenic progenitors (FAPs), play important roles in muscle ...
Charlene Redhead +7 more
doaj +1 more source