Evidence for acute contraction-induced myokine secretion by C2C12 myotubes [PDF]
PLoS ONE, 2018 Skeletal muscle is considered a secretory organ that produces bioactive proteins known as myokines, which are released in response to various stimuli.
Nobuharu L Fujii
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Ergogenic effects of caffeine are mediated by myokines [PDF]
Frontiers in Sports and Active Living, 2022 Exercise has long been known to effectively improve and enhance skeletal muscle function and performance. The favorable effects of exercise on remote organs other than skeletal muscle are well known, but the underlying mechanism has remained elusive ...
Shingo Takada +4 more
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Exercise training mode effects on myokine expression in healthy adults: A systematic review with meta-analysis [PDF]
Journal of Sport and Health ScienceBackground: The benefits of exercise are well known; however, many of the underlying molecular mechanisms are not fully understood. Skeletal muscle secretes myokines, which mediate muscle–organ crosstalk.
Francesco Bettariga +8 more
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The effect of eight weeks of aerobic exercise with moderate and high intensities on serum irisin and PGC-1α protein levels in obese male Wistar rats [PDF]
Journal of Shahrekord University of Medical Sciences, 2021 Background and aims: Irisin myokine whose secretion is induced by exercise is associated with an increase in thermogenesis. However, the effect of aerobic exercise with different intensities on the production and release of irisin in overweight ...
Seyyed Reza Attarzadeh Hosseini +3 more
doaj +1 more source
Sarcopenia and blood myokine levels as prognostic biomarkers in patients with liver cirrhosis or hepatocellular carcinoma [PDF]
Clinical and Molecular Hepatology, 2020 Sooyeon Oh, Jooho Lee
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Exercise training and muscle-cartilage cross-talk: A potential therapeutic target for osteoarthritis [PDF]
Journal of Exercise & Organ Cross Talk, 2022 Dear Editor-in-ChiefOsteoarthritis (OA) is a progressive disease and up to now, no effective cure has been found for these diseases. OA was characterized by destruction of articular cartilage (extracellular matrix).
Zahra Sajadi +2 more
doaj +1 more source
Frontiers in Physiology, 2021 Exercise not only produces beneficial effects on muscle itself via various molecular pathways, but also mediates the interaction between muscles and other organs in an autocrine/paracrine manner through myokines, which plays a positive role in ...
Chunlian Ma +5 more
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Effects of exercise on myokine gene expression in horse skeletal muscles [PDF]
Asian-Australasian Journal of Animal Sciences, 2019 Objective To examine the regulatory effects of exercise on myokine expression in horse skeletal muscle cells, we compared the expression of several myokine genes (interleukin 6 [IL-6], IL-8, chemokine [C-X-C motif] ligand 2 [CXCL2], and chemokine [C-C ...
Hyo Gun Lee +6 more
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Roles of Skeletal Muscle-Derived Exosomes in Organ Metabolic and Immunological Communication
Frontiers in Endocrinology, 2021 Skeletal muscles secrete various factors, such as proteins/peptides, nucleotides, and metabolites, which are referred to as myokines. Many of these factors are transported into extracellular bodily fluids in a free or protein-bound form.
Wataru Aoi, Yuko Tanimura
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Frontiers in Physiology, 2023 Osteoarthritis (OA) is the most prevalent chronic joint disease, with physical exercise being a widely endorsed strategy in its management guidelines. Exerkines, defined as cytokines secreted in response to acute and chronic exercise, function through ...
Shuangshuo Jia, Ziyao Yu, Lunhao Bai
doaj +1 more source