Results 121 to 130 of about 8,085 (246)
Myokine Irisin and Its Effects Linking Bone and Muscle Function
, 2018 Irisin is a myokine secreted by the skeletal muscle during physical activity both in mice and humans. Its first identified role was to activate the browning response in white adipocytes, subsequently triggering non-shivering thermogenesis; therefore ...
Giacomina Brunetti +7 more
core +1 more source
Frontiers in ImmunologyPurposeInterlukin-15 (IL-15) is an inflammatory cytokine that plays a vital role in immunology and obesity-associated metabolic syndrome. We performed this systematic review and meta-analysis to investigate whether exercise promotes circulating IL-15 ...
Mousa Khalafi +7 more
doaj +1 more source
Brain and Behavior, Volume 16, Issue 6, June 2026.ABSTRACT Purpose This study examined the relationship between body composition and cardiac autonomic nervous system activity in educators. The objective was to explore the associations between body fat mass (BFM) and fat‐free mass (FFM) with different heart rate variability (HRV) indices in a sample of educators and to assess whether FFM moderates the ...
Estela Álvarez‐Gallardo +4 more
wiley +1 more source
BiomedicinesIn the context of the global COVID-19 pandemic, understanding the intricate mechanisms of the body’s response to infection and inflammation has become a priority for the medical and research communities. It has been proven that during COVID-19 infection,
Alicja Mińko +5 more
doaj +1 more source
FGF21 as a Hepatokine, Adipokine, and Myokine in Metabolism and Diseases [PDF]
Frontiers in Endocrinology, 2014 Fibroblast growth factor (FGF) family members are mostly secreted as signaling proteins with diverse functions in development and metabolism. FGF21 is a unique FGF with metabolic, but not proliferative activities. FGF21 is mostly induced by different kinds of stress and acts though FGF receptor 1c with β-Klotho as a cofactor in an endocrine or, in ...
openaire +3 more sources
Brain and Behavior, Volume 16, Issue 6, June 2026.In this review, we discuss the scientific basis for how neurocognitive aging occurs after critical illness, including sepsis, trauma, and burns, and the clinical need to develop therapies to reduce inflammation, protect the blood–brain barrier, remove senescent cells, and enhance neuroplasticity.
Errin Lawrence +14 more
wiley +1 more source
CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.This review systematically explores exercise as a multi‐target intervention for RBD, highlighting its mechanisms of action and regulatory effects on key pathophysiological processes. ABSTRACT Backgrounds REM sleep behavior disorder (RBD) is a prodromal non‐motor symptom of Parkinson's disease (PD) and other α‐synucleinopathies, affecting approximately ...
Xinhui Qiu +4 more
wiley +1 more source
, 2017 Kidney injury initiates metabolic reprogramming in tubule cells that contributes to the development of chronic kidney disease (CKD). Exercise has been associated with beneficial effects in patients with CKD.
Brett H. Graham +11 more
core +1 more source
Hydrogen Sulfide and Irisin, Potential Allies in Ensuring Cardiovascular Health
AntioxidantsIrisin is a myokine secreted under the influence of physical activity and exposure to low temperatures and through different exogenous stimuli by the cleavage of its precursor, fibronectin type III domain-containing protein 5 (FNDC5).
Lorenzo Flori +3 more
doaj +1 more source
Health Science Reports, Volume 9, Issue 6, June 2026.ABSTRACT Background and Aims Osteosarcopenia, defined as the coexistence of osteoporosis and sarcopenia, is an emerging geriatric syndrome linked to the musculoskeletal decline associated with aging. It is correlated with an increased risk of falls, fractures, disability, and mortality.
Javeria Taj +6 more
wiley +1 more source