Results 101 to 110 of about 11,761 (240)

Myostatin inhibits osteoblastic differentiation by suppressing osteocyte-derived exosomal microRNA-218: A novel mechanism in muscle-bone communication [PDF]

, 2017
Muscle and bone are closely associated in both anatomy and function, but the mechanisms that coordinate their synergistic action remain poorly defined. Myostatin, a myokine secreted by muscles, has been shown to inhibit muscle growth, and the disruption ...
Bauman, William A., Bonewald, Lynda F., Cardozo, Christopher, Divieti Pajevic, Paola, Ksiezak-Reding, Hanna, Pan, Jianping, Peng, Yuanzhen, Qin, Weiping, Qin, Yiwen, Wu, Yingjie, Zhao, Wei   +10 more
core   +1 more source

Myokines, Measurement, and Technical Considerations

, 2023
No Skeletal muscle has long been established as a highly multifunctional organ, playing a vital role in locomotion, whole-body metabolic and energy homeostasis, and thermoregulation. More recently, emergent evidence has highlighted a potent secretory role for muscle, producing and releasing “myokine” molecules that act in autocrine, paracrine, or ...
Willis, Craig R.G., Deane, C.S., Etheridge, T.   +2 more
openaire   +2 more sources

A multi‐omics investigation of sarcopenia and frailty: Integrating genomic, epigenomic and telomere length data

Experimental Physiology, EarlyView.
Abstract Sarcopenia and frailty are complex geriatric syndromes influenced by a combination of genetic and environmental factors. Recent studies suggest that specific genetic variants, DNA methylation patterns and shortened telomeres are associated with age‐related diseases and might contribute to the development of both sarcopenia and frailty. In this
Valentina Ginevičienė, Erinija Pranckevičienė, Alina Urnikytė, Laura Jurkūnaitė, Kristijona Gutauskaitė, Rūta Dadelienė, Justina Kilaitė, Ieva Eglė Jamontaitė, Asta Mastavičiūtė, Ildus I. Ahmetov, Vidmantas Alekna   +10 more
wiley   +1 more source

Functional body composition and related aspects in research on obesity and cachexia: report on the 12th Stock Conference held on 6 and 7 September 2013 in Hamburg, Germany [PDF]

, 2014
The 12th Stock Conference addressed body composition and related functions in two extreme situations, obesity and cancer cachexia. The concept of ‘functional body composition’ integrates body components into regulatory systems relating the mass of organs
Ahima, Antoun, Arita, Armstrong, Baracos, Barker, Benedict, Berg, Bing, Bing, Bortoluzzi, Bostrom, Boström, Bosy-Westphal, Braun, Canani, Cianfarani, Cole, Compston, Dahlman, De Laet, Delmonico, DiGirolamo, Ding, Drøyvold, Drøyvold, Dulloo, Dulloo, Dulloo, Dulloo, Dulloo, Elkasrawy, Faith, Fearon, Fearon, Fomon, Forbes, Frontera, Gallagher, Godfrey, Goodpaster, Griffith, Hack, Hall, Hall, Hall, Hall, Hall, Hallgreen, Hartwig, Haugen, Heilbronn, Henningsen, Heymsfield, Hotamisligil, Hotamisligil, Hotta, Johannesdottir, Johns, Johnson, Kelley, Keys, Kohrt, Kugel, Lagerpusch, Lagerpusch, Lang, Langlois, Larsen, Later, Leibel, Li, Lieffers, Lieffers, Martin, Montani, Mori, Mracek, Müller, Müller, Müller, Müller, Müller, Müller, Ouchi, Parsons, Pedersen, Pedersen, Pedersen, Perrini, Prado, Prado, Rajala, Raschke, Raschke, Raschke, Ravussin, Rebelos, Rosen, Rosenbaum, Rudolf, Schaap, Schwartz, Shen, Sjöblom, Song, Spalding, Stephens, Stock, Swinburn, Szulc, Sørensen, Sørensen, Taaffe, Trayhurn, Trayhurn, Trayhurn, Trayhurn, Tschöp, Walsh, Wells, Wong, Wu, Yamauchi, Yokota, Yoon, Zampieri, Zhang, Zimmermann   +128 more
core   +2 more sources

Seven days of warm‐water immersion enhances resting irisin and BDNF, but not klotho, in older men

Experimental Physiology, EarlyView.
Abstract We examined whether seven consecutive days of warm‐water immersion could elevate resting and exercise‐induced levels of brain‐derived neurotrophic factor (BDNF), irisin and klotho in older adults. These biomarkers support cognitive and metabolic health, but their levels decline with age.
Joel M Garrett, James J McCormick, Kelli E King, Kristina‐Marie T Janetos, Nathalie V Kirby, Fergus K O'Connor, Glen P Kenny   +6 more
wiley   +1 more source

Exercise and skeletal muscle regeneration

Journal of Physical Fitness and Sports Medicine, 2012
Skeletal muscle injury is generally caused by stimuli, such as intense resistance training, eccentric muscle contraction, muscle strain and bruising. Injured skeletal muscles are repaired within several weeks after injury, because skeletal muscle has a ...
Mitsutoshi Kurosaka, Shuichi Machida
doaj   +1 more source

Irisina y envejecimiento [PDF]

, 2018
El envejecimiento es un proceso natural complejo que aborda un amplio espectro de cambios físicos y fisiológicos, y que puede conllevar la aparición dediferentes enfermedades relacionadas.
Carrasco Blanco, Alberto
core  

Irisin and FNDC5 in retrospect: An exercise hormone or a transmembrane receptor? [PDF]

, 2013
FNDC5 (fibronectin domain-containing [protein] 5) was initially discovered and characterized by two groups in 2002. In 2011 FNDC5 burst into prominence as the parent of irisin, a small protein containing the fibronectin type III domain.
Erickson, HP
core   +1 more source

Influence of oestradiol on exercise induced muscular damage and heart rate variability in a non‐trained healthy population

Experimental Physiology, EarlyView.
Abstract This study evaluates in non‐trained healthy women the influence of oestradiol (E2) on exercise induced muscular damage (EIMD) and performance. Thirty‐six young healthy women performed a step‐exercise until exhaustion, assessing the number of repetitions, pain perception and well‐being (questionnaires, 15 min and at 48 h post‐exercise), blood ...
David Ramiro‐Cortijo, Ricardo Alonso de Celada, Pilar Rodríguez‐Rodríguez, Stefanny Lozano Gutiérrez, Leonardo Betancourt, Santiago Ruvira, Silvia M. Arribas   +6 more
wiley   +1 more source

Sarcopenia and blood myokine levels as prognostic biomarkers in patients with liver cirrhosis or hepatocellular carcinoma [PDF]

Clinical and Molecular Hepatology, 2020
Sooyeon Oh, Jooho Lee
doaj   +1 more source