Results 101 to 110 of about 8,085 (246)
Seven days of warm‐water immersion enhances resting irisin and BDNF, but not klotho, in older men
Experimental Physiology, EarlyView.Abstract We examined whether seven consecutive days of warm‐water immersion could elevate resting and exercise‐induced levels of brain‐derived neurotrophic factor (BDNF), irisin and klotho in older adults. These biomarkers support cognitive and metabolic health, but their levels decline with age.
Joel M Garrett +6 more
wiley +1 more source
Experimental Physiology, EarlyView.Abstract This study evaluates in non‐trained healthy women the influence of oestradiol (E2) on exercise induced muscular damage (EIMD) and performance. Thirty‐six young healthy women performed a step‐exercise until exhaustion, assessing the number of repetitions, pain perception and well‐being (questionnaires, 15 min and at 48 h post‐exercise), blood ...
David Ramiro‐Cortijo +6 more
wiley +1 more source
The myokine irisin stimulates osteoclast differentiation and function
, 2020 Thomas Maciag Award for Excellence in Basic & Translational Science- Trainee 1st Place Award - Scientific Talk Eben Estell, PhD, Research Fellow, Clifford J.
Kim, H +6 more
core
Myokine Musclin Is Critical for Exercise-Induced Cardiac Conditioning
, 2023 This study investigates the role and mechanisms by which the myokine musclin promotes exercise-induced cardiac conditioning. Exercise is one of the most powerful triggers of cardiac conditioning with proven benefits for healthy and diseased hearts. There
Denice M. Hodgson-Zingman +6 more
core +1 more source
Sarcopenia and blood myokine levels as prognostic biomarkers in patients with liver cirrhosis or hepatocellular carcinoma [PDF]
Clinical and Molecular Hepatology, 2020 Sooyeon Oh, Jooho Lee
doaj +1 more source
Revista de la Sociedad Argentina de Diabetes, 2022 Skeletal muscle (SM) is not only a locomotor unit responsible for the propulsion and regulation of energy and metabolic processes. Now it is also recognized as an organ capable of producing molecules with vital functions: the so-called myokines1. Over the past two decades, it has become apparent that the ME functions as an endocrine organ in response ...
openaire +1 more source
Experimental Physiology, EarlyView.Abstract Klotho, a pleiotropic protein initially identified for its role in kidney function, has garnered significant attention for its neuroprotective properties in various neurodegenerative diseases. It regulates key processes, such as oxidative stress, neuroinflammation, synaptic plasticity and myelination, all crucial for maintaining neuronal ...
Amir Arsalan Ghahari +7 more
wiley +1 more source
Intramuscular pathways of maladaptation in overtraining syndrome
The Journal of Physiology, EarlyView.Abstract figure legend The transition from adaptive overreaching to maladaptive overtraining and mechanisms through which excessive training load can lead to performance decline. Four interconnected pathophysiological domains are highlighted: neural fatigue, involving both central and peripheral components such as altered sensory feedback and reflex ...
Emily Shorter +4 more
wiley +1 more source
Potential health benefits of cold‐water immersion: the central role of PGC‐1α
The Journal of Physiology, EarlyView.Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer +2 more
wiley +1 more source
Treating age‐related loss of muscle mass and function: Where should we be focusing?
The Journal of Physiology, EarlyView.Abstract figure legend Perturbations contributing to the age‐related loss of muscle mass and strength. A, in the spinal cord, self‐reinforcing cycles of oxidative stress, mitochondrial dysfunction and inflammation mediated by cells, including microglia, contribute to motor neuron degeneration.
Daniel J. Ham +4 more
wiley +1 more source