Results 91 to 100 of about 8,845 (203)
Can irisin be a linker between physical activity and brain function?
Biomolecular Concepts, 2016 Irisin was initially discovered as a novel hormone-like myokine released from skeletal muscle during exercise to improve obesity and glucose dysfunction by stimulating the browning of white adipose tissue.
Zhang Jing, Zhang Weizhen
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Potential health benefits of cold‐water immersion: the central role of PGC‐1α
The Journal of Physiology, EarlyView.Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer +2 more
wiley +1 more source
Myokines and interorgan crosstalk: bridging exercise to health promotion and disease prevention [PDF]
Annals of Pediatric Endocrinology & MetabolismExercise is known to promote physical health and reduce the risk of various diseases. During exercise, skeletal muscle actively contracts to perform movements and secretes hormone-like molecules termed myokines.
Junseo Ha, Suchan Sung, Hyeonwoo Kim
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The Journal of Physiology, EarlyView.Abstract figure legend In the muscular layer of long‐standing diabetic bladders increased myostatin expression promotes tissue remodelling by reducing the muscle‐to‐collagen ratio, ultimately diminishing bladder contractility. Maximal elastance – defined as the slope of the end‐emission pressure–volume relationship (EPR), derived from the regression ...
Cheng‐Yuan Lai +6 more
wiley +1 more source
Frontiers in ImmunologyPurposeInterlukin-15 (IL-15) is an inflammatory cytokine that plays a vital role in immunology and obesity-associated metabolic syndrome. We performed this systematic review and meta-analysis to investigate whether exercise promotes circulating IL-15 ...
Mousa Khalafi +7 more
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The Journal of Physiology, EarlyView.Abstract figure legend Skeletal muscle structure was analysed at three levels in young vs. aged humans, and in young vs. aged mice subjected to unilateral hindlimb immobilization to model disuse. (1) Macroscopic: magnetic resonance imaging of the thigh (human) and wet mass of individual hindlimb muscles (mouse) revealed that both ageing and disuse ...
Ramy K. A. Sayed +13 more
wiley +1 more source
Interleukin-6 and exercise; early evidence of a novel myokine [PDF]
, 2018 Interleukin-6 (IL-6) was first identified as a pleiotropic cytokine, with a host of body-wide functions. Cytokine functions are characterized by chronically elevated levels within various inflammatory states.
Hogg, Brendan, Mr.
core
, 2017 Kidney injury initiates metabolic reprogramming in tubule cells that contributes to the development of chronic kidney disease (CKD). Exercise has been associated with beneficial effects in patients with CKD.
Brett H. Graham +11 more
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BiomedicinesIn the context of the global COVID-19 pandemic, understanding the intricate mechanisms of the body’s response to infection and inflammation has become a priority for the medical and research communities. It has been proven that during COVID-19 infection,
Alicja Mińko +5 more
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Health Science Reports, Volume 9, Issue 10, October 2026.ABSTRACT Background and Aims Type 2 diabetes (T2D) is a major global health challenge, primarily driven by insulin resistance and progressive β‐cell dysfunction aggravated by chronic low‐grade inflammation. Skeletal muscle has emerged as a pivotal endocrine organ through the secretion of myokines, which exert systemic metabolic and immunomodulatory ...
Christian Tague +3 more
wiley +1 more source