Results 81 to 90 of about 8,845 (203)

Sarcopenia and blood myokine levels as prognostic biomarkers in patients with liver cirrhosis or hepatocellular carcinoma [PDF]

Clinical and Molecular Hepatology, 2020
Sooyeon Oh, Jooho Lee
doaj   +1 more source

Exercise and skeletal muscle regeneration

Journal of Physical Fitness and Sports Medicine, 2012
Skeletal muscle injury is generally caused by stimuli, such as intense resistance training, eccentric muscle contraction, muscle strain and bruising. Injured skeletal muscles are repaired within several weeks after injury, because skeletal muscle has a ...
Mitsutoshi Kurosaka, Shuichi Machida
doaj   +1 more source

A multi‐omics investigation of sarcopenia and frailty: Integrating genomic, epigenomic and telomere length data

Experimental Physiology, EarlyView.
Abstract Sarcopenia and frailty are complex geriatric syndromes influenced by a combination of genetic and environmental factors. Recent studies suggest that specific genetic variants, DNA methylation patterns and shortened telomeres are associated with age‐related diseases and might contribute to the development of both sarcopenia and frailty. In this
Valentina Ginevičienė, Erinija Pranckevičienė, Alina Urnikytė, Laura Jurkūnaitė, Kristijona Gutauskaitė, Rūta Dadelienė, Justina Kilaitė, Ieva Eglė Jamontaitė, Asta Mastavičiūtė, Ildus I. Ahmetov, Vidmantas Alekna   +10 more
wiley   +1 more source

Seven days of warm‐water immersion enhances resting irisin and BDNF, but not klotho, in older men

Experimental Physiology, EarlyView.
Abstract We examined whether seven consecutive days of warm‐water immersion could elevate resting and exercise‐induced levels of brain‐derived neurotrophic factor (BDNF), irisin and klotho in older adults. These biomarkers support cognitive and metabolic health, but their levels decline with age.
Joel M Garrett, James J McCormick, Kelli E King, Kristina‐Marie T Janetos, Nathalie V Kirby, Fergus K O'Connor, Glen P Kenny   +6 more
wiley   +1 more source

Acute exercise‐induced lipolysis and increase in levels of fatty acid esters of hydroxy fatty acids in adipose tissue are impaired in obese and aged mice

Experimental Physiology, EarlyView.
Abstract Improving adipose tissue (AT) metabolism through exercise might increase production of lipokines from the fatty acid esters of hydroxy fatty acids (FAHFA) family. Although exercise training can increase insulin sensitivity and levels of specific FAHFA in AT and the circulation in humans, the effects of acute exercise on FAHFA levels remain ...
Marko Mitrovic, Olga Horakova, Martin Riecan, Veronika Kleinova, Tomas Cajka, Lenka Rossmeislova, Ondrej Kuda, Martin Rossmeisl   +7 more
wiley   +1 more source

Putting the brakes on muscle growth: Myostatin as regulator of disuse atrophy

Experimental Physiology, EarlyView.
Abstract Skeletal muscle is a highly plastic tissue that rapidly adapts to changes in mechanical loading and metabolic activity. Periods of inactivity, including bed rest, limb immobilization or microgravity, induce a pronounced loss of muscle mass and function.
Derk H. C. Nieuwenhuijsen, Moritz Eggelbusch, Rob C. I. Wüst   +2 more
wiley   +1 more source

Acute and lifelong exercise modulate the tumorigenic potential of human lung cancer cells and their susceptibility to cisplatin

Experimental Physiology, EarlyView.
Abstract The association between higher levels of physical activity and lower cancer risk and mortality is well established. However, a causal link is yet to be proven. Recent studies showed a decrease in the proliferation rates of cultured human cancer cells when the human serum used to stimulate them was conditioned by acute exercise. Here, we tested
Carlos M. Soares, João P. Moura, Leonardo M. R. Ferreira, Ana Pedrosa, Pedro Filipe, Luís Rama, Ana M. Teixeira, Ana M. Urbano   +7 more
wiley   +1 more source

Exercise-Induced Changes in Circulating Exerkines Associated with Brain Health: A Systematic Review and Meta-Analysis in Healthy Populations

Sci
Exerkines are released in response to physical exercise and play a key role in promoting health, such as taking part in modulating brain morphology and function.
Songxin Tang, Raquel Pedrero-Chamizo, Eva Gesteiro, Carlos Quesada-González, Margarita Pérez-Ruiz, Marcela González-Gross   +5 more
doaj   +1 more source

Intramuscular pathways of maladaptation in overtraining syndrome

The Journal of Physiology, EarlyView.
Abstract figure legend The transition from adaptive overreaching to maladaptive overtraining and mechanisms through which excessive training load can lead to performance decline. Four interconnected pathophysiological domains are highlighted: neural fatigue, involving both central and peripheral components such as altered sensory feedback and reflex ...
Emily Shorter, Oscar Horwath, Sabrina Tzivia Barsky, Ferdinand von Walden, Johanna T. Lanner   +4 more
wiley   +1 more source

The Dual Role of Interleukin-6 in the Pathophysiology of Skeletal Muscle: Mechanisms, Challenges, and Therapeutic Prospects

Pharmaceuticals
Interleukin-6 (IL-6) is a cytokine with multiple biological effects. It plays a complex and seemingly paradoxical central role in both the physiological homeostasis and pathological processes of skeletal muscle.
Yingyu Wang, Jitai Zhang, Jie Wang, Yijie Zhang, Jiacheng Sun, Jiahuan Gong, Xinlei Yao, Hualin Sun   +7 more
doaj   +1 more source