Results 111 to 120 of about 8,845 (203)

Aging of Skeletal Muscle: From Molecular Mechanisms to Therapeutic Interventions

MedComm, Volume 7, Issue 10, October 2026.
Skeletal muscle aging is driven by coordinated local breakdown across myofibers, stem and stromal cells, immune and vascular compartments, and neuromuscular control. These mechanisms promote mitochondrial dysfunction, inflammation, senescence, impaired regeneration, fibrosis, myosteatosis, denervation, and functional decline.
Ting Liu, Yaomin Hu
wiley   +1 more source

Relaxin‐2: Shaping the Proteomic Landscape of Skeletal Muscle Physiology, Glucose Trafficking, and Mitochondrial Function in Rat

The FASEB Journal, Volume 40, Issue 18, 30 September 2026.
Cardioprotective hormone relaxin‐2 showed relevant effects on rat skeletal muscle by altering proteins linked to muscle function, regeneration, differentiation, mitochondrial function, glucose metabolism, and structural integrity and organization. Specifically, relaxin‐2 reduced the expression of 95 proteins, increased 32, and elicited unique proteins ...
Xocas Vázquez‐Abuín, Lucía Gómez‐Cibeira, Javier García‐Seara, Pablo de la Fuente‐López, Carlos Minguito‐Carazo, Susana B. Bravo, Manuel Otero‐Santiago, Oreste Gualillo, José Ramón González‐Juanatey, Francisca Lago, Sandra Feijóo‐Bandín, Alana Aragón‐Herrera   +11 more
wiley   +1 more source

Effects of Aerobic Exercise in the Enriched and Non-enriched Environments on Serum Levels of Cathepsin B and Doublecortin in Adult Females [PDF]

یافته
Background: Cathepsin B (CTSB) and doublecortin (DCX) have positive effects on cognitive function, but the effect of aerobic exercise in the enriched and non-enriched environments on serum levels of these factors in adult females has not been ...
Hamza Saeed Jawad Kazim Al-Dalfi, Vahid Valipour Dehnou   +1 more
doaj  

Differences in the Impact of Various Types of Exercise on Irisin Levels: A Systematic Review and Meta-Analysis

International Journal of Preventive Medicine
Background: Irisin, a myokine that is responsive to exercise, induces significant changes in subcutaneous adipose tissue. By promoting the browning of white fat tissue, it enhances energy expenditure, thereby addressing overweight and obesity.
Atefe Torabi, Jalil Reisi, Mehdi Kargarfard, Marjan Mansourian   +3 more
doaj   +1 more source

Parsing cause from consequence in blood flow restriction training: Insights from integrated human physiology

The Journal of Physiology, EarlyView.
Coral L. Murrant
wiley   +1 more source

SIRT1 in Neurodegenerative Diseases: Molecular Mechanisms, Disease Relevance, and Therapeutic Potential

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
SIRT1, an NAD+‐dependent deacetylase, supports cognitive resilience by coordinating neuroprotection, synaptic plasticity, autophagy–lysosomal proteostasis, and mitochondrial energy homeostasis. Reduced or dysregulated SIRT1 is associated with protein aggregation, neuroinflammation, mitochondrial dysfunction, synaptic loss, and cognitive decline in ...
Jiabin Duan, Jiaqi Liu, Qingsheng Meng, Jiahao Liu, Sitian Yang, Fang Zhou, Jing Cao   +6 more
wiley   +1 more source

Acute and chronic exercise effects on myokine expression and cancer suppression in survivors of breast cancer

This research aimed to investigate the effects of different exercise modes on myokine expression and cancer cell suppression in survivors of breast cancer.
Bettariga, Francesco
core   +1 more source

Mechanistic Pathways of Wound Healing: From Hemostasis to Scar‐Free Regeneration

Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT Wound healing is the critical process regulated through a harmonious coordination of cellular, molecular, pathological, and systemic communications. Normally, healing occurs in four overlapping phases, which are modified and controlled by various growth factor interactions and signaling pathways.
Devadass Jessy Mercy, Koyeli Girigoswami, Agnishwar Girigoswami   +2 more
wiley   +1 more source

Crosstalk Between Cortical Plasticity and Peripheral Nervous Injury: Insights, Mechanisms, and Future Directions

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
Peripheral nerve injury induces dynamic cortical plasticity, driven by molecular mechanisms such as BDNF and neurotransmitter systems. This review synthesizes subtype‐specific plasticity patterns: compressive injuries trigger rapid reorganization, while metabolic neuropathies lead to maladaptive changes.
Cong Cheng, Dong Gao, Yaojie Shen, Xi Wang, Junxi Dai, Yaoxian Xiang, Zongyuan Jiang, Zongqi You, Junjian Jiang   +8 more
wiley   +1 more source

Exercise-Induced Irisin, the Fat Browning Myokine, as a Potential Anticancer Agent

, 2019
Irisin is a recently discovered myokine that plays an important role in fat metabolism through the browning of white adipose tissue. This myokine is usually secreted after exercise by improving energy balance and has shown great potential as a possible ...
George-Emmanuel Maalouf, Diala El Khoury
core   +1 more source