Results 111 to 120 of about 8,085 (246)
Exercise-Induced Myokine Response Following 75-km Cycling [PDF]
, 2016 Myokine is a term referring to a variety of cytokines or chemokines that are produced and released by myocytes in response to skeletal muscle contractions. The myokine response to prolonged exercise is not well known. Therefore, the purpose of this study
NC DOCKS at Appalachian State University +1 more
core +1 more source
Can irisin be a linker between physical activity and brain function?
Biomolecular Concepts, 2016 Irisin was initially discovered as a novel hormone-like myokine released from skeletal muscle during exercise to improve obesity and glucose dysfunction by stimulating the browning of white adipose tissue.
Zhang Jing, Zhang Weizhen
doaj +1 more source
SciExerkines are released in response to physical exercise and play a key role in promoting health, such as taking part in modulating brain morphology and function.
Songxin Tang +5 more
doaj +1 more source
NutrientsObesity and osteoarthritis (OA) are increasingly prevalent conditions that are intricately linked, with each exacerbating the other’s pathogenesis and worsening patient outcomes. This review explores the dual impact of obesity on OA, highlighting the role of excessive weight in aggravating joint degeneration and the limitations OA imposes on physical ...
Daniel Vasile Timofte +3 more
openaire +2 more sources
Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis
Advanced Science, Volume 13, Issue 32, 9 June 2026.This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu +15 more
wiley +1 more source
, 2019 Myokines are peptides known to modulate brain neuroplasticity, adipocyte metabolism, bone mineralization, endothelium repair and cell growth arrest in colon and breast cancer, among other processes.
Pareja-Galeano, Helios +14 more
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Myokines and interorgan crosstalk: bridging exercise to health promotion and disease prevention [PDF]
Annals of Pediatric Endocrinology & MetabolismExercise is known to promote physical health and reduce the risk of various diseases. During exercise, skeletal muscle actively contracts to perform movements and secretes hormone-like molecules termed myokines.
Junseo Ha, Suchan Sung, Hyeonwoo Kim
doaj +1 more source
Lactate as a major myokine and exerkine
Nature Reviews Endocrinology, 2022 George A. Brooks +7 more
openaire +4 more sources
Animal Genetics, Volume 57, Issue 3, June 2026.ABSTRACT The intramuscular fat (IMF) content is an important indicator of meat quality, affecting the sensory properties of meat. IMF is a complex trait with polygenic nature. This research aimed to identify differentially expressed (DE) genes and key transcription factors (TFs) associated with IMF deposition in the liver of two rabbit lines ...
Jesús Valdés‐Hernández +4 more
wiley +1 more source
Myokine Secretion Dynamics and Their Role in Critically Ill Patients: A Scoping Review
Background/Objectives: Myokines can modulate organ function and metabolism, offering a protective profile against ICU complications beyond preventing local muscle wasting.
Jalil Contreras, Yorschua Frederick +11 more
core +1 more source