Results 11 to 20 of about 6,457 (246)
A new member of the myokine family: Irisin
Medicine Science, 2017 Skeletal muscle is an important tissue which functions as an endocrine organ and secretes the factors called myokine. Irisin is a thermogenic peptide which has been recently defined as a new myokine.
Cigdem Tekin +2 more
doaj +3 more sources
The role of myokines in muscle health and disease [PDF]
Current Opinion in Rheumatology, 2016 Purpose of review This article updates on the concept that muscle-derived cytokines (myokines) play important roles in muscle health and disease. Recent findings Interleukin-6 (IL-6) is released from normal skeletal muscle in response to exercise, mediating both anti-inflammatory ...
Adam P. Lightfoot, Robert Cooper
openalex +5 more sources
A Role for Myokines in Muscle-Bone Interactions [PDF]
Exercise and Sport Sciences Reviews, 2010 This review presents the hypothesis that muscle is a source of secreted factors (myokines) that can influence bone mass in both positive and negative ways. Growth factor secretion by muscle may therefore be one pathway through which mechanical signals are transduced biologically.
Mark W. Hamrick
openalex +4 more sources
Myokines and Resistance Training: A Narrative Review [PDF]
International Journal of Molecular Sciences, 2022 In the last few years, the muscular system has gained attention due to the discovery of the muscle-secretome and its high potency for retaining or regaining health. These cytokines, described as myokines, released by the working muscle, are involved in anti-inflammatory, metabolic and immunological processes. These are able to influence human health in
Beate E. M. Zunner +8 more
openalex +4 more sources
Connecting Myokines and Metabolism [PDF]
Endocrinology and Metabolism, 2015 Skeletal muscle is the largest organ of the body in non-obese individuals and is now considered to be an endocrine organ. Hormones (myokines) secreted by skeletal muscle mediate communications between muscle and liver, adipose tissue, brain, and other organs.
Hyeong Kyu Park, Rexford S. Ahima
openaire +3 more sources
Adipokines, Myokines, and Cardiokines: The Role of Nutritional Interventions [PDF]
International Journal of Molecular Sciences, 2020 It is now established that adipose tissue, skeletal muscle, and heart are endocrine organs and secrete in normal and in pathological conditions several molecules, called, respectively, adipokines, myokines, and cardiokines. These secretory proteins constitute a closed network that plays a crucial role in obesity and above all in cardiac diseases ...
Pamela Senesi +2 more
openalex +4 more sources
Myokines in Acromegaly: An Altered Irisin Profile [PDF]
Frontiers in Endocrinology, 2021 IntroductionThe muscle is an endocrine organ controlling metabolic homeostasis. Irisin and myostatin are key myokines mediating this process. Acromegaly is a chronic disease with a wide spectrum of complications, including metabolic disturbances.PurposeTo examine the influence of acromegaly on irisin and myostatin secretion and their contribution to ...
Agnieszka Zembska +7 more
openaire +4 more sources
Adjuvant pharmacological strategies for the musculoskeletal system during long‐term space missions
British Journal of Clinical Pharmacology, EarlyView., 2023 Abstract Despite 2 h of daily exercise training, muscle wasting and bone loss are still present after 6‐month missions to the international space station. Some crew members lose bone much faster than others. In preparation for missions to the Moon and Mars, space agencies are therefore reviewing their countermeasure portfolios.
Friederike Thomasius +2 more
wiley +1 more source
The Role of Myokines in Liver Diseases. [PDF]
Int J Mol SciMyokine is a general term for hormones, peptides, and other substances secreted by skeletal muscle. Myokine has attracted much attention in recent years as a key substance for understanding the mechanism of “exercise and health”. Skeletal muscle accounts for about 40% of the total human weight and is now recognized as an endocrine organ that produces ...
Nishikawa H, Kim SK, Asai A.
europepmc +2 more sources
FGF21 is an Akt‐regulated myokine [PDF]
FEBS Letters, 2008 Fibroblast growth factor‐21 (FGF21) functions as a metabolic regulator. The FGF21 transcript is reported to be abundantly expressed in liver, but little is known about the regulation of FGF21 expression in other tissues. In this study, we show that levels of FGF21 protein expression were similar in skeletal muscle and liver from fasted mice.
Yuichi Akasaki +5 more
openaire +2 more sources