Results 21 to 30 of about 6,457 (246)
Irisin: A myokine with locomotor activity [PDF]
Neuroscience Letters, 2015 The mechanisms underlying alterations in brain functions in response to physical exercise are not fully understood. The present study examined the central effect of irisin, a 112 amino acid polypeptide hormone secreted from the skeletal muscle after exercise, on the locomotion in rats.
Chao Zhang +9 more
openaire +3 more sources
Drosophila PDGF/VEGF signaling from muscles to hepatocyte-like cells protects against obesity
eLife, 2020 PDGF/VEGF ligands regulate a plethora of biological processes in multicellular organisms via autocrine, paracrine, and endocrine mechanisms. We investigated organ-specific metabolic roles of Drosophila PDGF/VEGF-like factors (Pvfs).
Arpan C Ghosh +7 more
doaj +1 more source
The impact of dietary intervention on myokines: a narrative review [PDF]
PharmaciaThis review elucidates the role of dietary factors in influencing myokine secretion, complementing the recognized benefits of physical activity on metabolic health.
Yavor Assyov +12 more
doaj +3 more sources
Identification of Sclerostin as a Putative New Myokine Involved in the Muscle-to-Bone Crosstalk
Biomedicines, 2021 Bone and muscle have been recognized as endocrine organs since they produce and secrete “hormone-like factors” that can mutually influence each other and other tissues, giving rise to a “bone–muscle crosstalk”.
Maria Sara Magarò +13 more
doaj +1 more source
Role of myokines and osteokines in cancer cachexia [PDF]
Experimental Biology and Medicine, 2021 Cancer-induced muscle wasting, i.e. cachexia, is associated with different types of cancer such as pancreatic, colorectal, lung, liver, gastric and esophageal. Cachexia affects prognosis and survival in cancer, and it is estimated that it will be the ultimate cause of death for up to 30% of cancer patients.
Fabrizio Pin +2 more
openaire +3 more sources
Myokine Regulation as Marker of Sarcopenia in Elderly
MCBS (Molecular and Cellular Biomedical Sciences), 2018 The elderly population will increase as well as increasing life expectancy. Health problems in elderly will be more complex and need a comprehensive management. One of the problems that arise from the aging process is sarcopenia.
I Gusti Putu Suka Aryana +2 more
doaj +1 more source
Frontiers in Physiology, 2020 Participation in a long-distance run, e.g., marathon or ultramarathon, continues to increase. One side effect of long-distance running is excessive inflammation manifested by the rise in inflammatory cytokine levels.
Jan Mieszkowski +5 more
doaj +1 more source
Frontiers in Aging Neuroscience, 2023 BackgroundThe world’s population is aging, but life expectancy has risen more than healthy life expectancy (HALE). With respect to brain and cognition, the prevalence of neurodegenerative disorders increases with age, affecting health and quality of life,
Wouter A. J. Vints +18 more
doaj +1 more source
Exercise-Induced Irisin Decreases Inflammation and Improves NAFLD by Competitive Binding with MD2
Cells, 2021 Non-alcoholic fatty liver disease (NAFLD) is a global clinical problem. The MD2-TLR4 pathway exacerbates NAFLD progression by promoting inflammation. Long-term exercise is considered to improve NAFLD but the underlying mechanism is still unclear. In this
Weiwei Zhu +7 more
doaj +1 more source
Artificial intelligence in decoding muscle–organ crosstalk: Unveiling myokine networks and therapeutic frontiers [PDF]
Journal of Exercise & Organ Cross TalkSkeletal muscle functions as an endocrine organ, secreting myokines that mediate crosstalk with organs like the brain, liver, adipose tissue, and vascular system, influencing metabolism, inflammation, and disease progression.
Ehsan Arabzadeh +2 more
doaj +1 more source