Results 31 to 40 of about 7,261 (223)

Effects of myokines on bone [PDF]

BoneKEy Reports, 2016
The links between muscle and bone have been recently examined because of the increasing number of patients with osteoporosis and sarcopenia. Myokines are skeletal muscle-derived humoral cytokines and growth factors, which exert physiological and pathological functions in various distant organs, including the regulation of glucose, energy and bone ...
openaire   +2 more sources

FGF21 as Modulator of Metabolism in Health and Disease

Frontiers in Physiology, 2019
Fibroblast growth factor 21 (FGF21) is a hormone that regulates important metabolic pathways. FGF21 is expressed in several metabolically active organs and interacts with different tissues.
Caterina Tezze, Caterina Tezze, Vanina Romanello, Vanina Romanello, Marco Sandri, Marco Sandri, Marco Sandri, Marco Sandri   +7 more
doaj   +1 more source

Muscle signals to the rescue

eLife, 2020
The skeletal muscle of fruit flies communicates with other organs to prevent the accumulation of too much fat and to protect adults against obesity.
Arely V Diaz, Tânia Reis
doaj   +1 more source

Physical exercise associated with NO production: Signaling pathways and significance in health and disease

Frontiers in Cell and Developmental Biology, 2015
Here we review available data on nitric oxide (NO)-mediated signaling in skeletal muscle during physical exercise. Nitric oxide modulates skeletal myocyte function, hormone regulation, and local microcirculation.
Elena Yu Dyakova, Leonid V Kapilevich, Victor G Shylko, Sergey V Popov, Yana eAnfinogenova   +4 more
doaj   +1 more source

Exercise and Conjugated Linoleic Acid Supplementation Induce Changes in the Composition of Liver Fatty Acids

Frontiers in Physiology, 2019
Exercise and supplementation with conjugated linoleic acid (CLA) are used to reduce body weight and to improve health. Applied together, they may exert a synergistic effect. However, the effects of exercise and CLA supplementation on liver metabolism are
Adriana Mika, Adriana Mika, Aleksandra Czumaj, Piotr Stepnowski, Filippo Macaluso, Filippo Macaluso, Filippo Macaluso, Giulio Spinoso, Rosario Barone, Rosario Barone, Valentina Di Felice, Valentina Di Felice, Tomasz Sledzinski   +12 more
doaj   +1 more source

Profiling of adenine‐derived signaling molecules, cytokinins, in myotubes reveals fluctuations in response to lipopolysaccharide‐induced cell stress

Physiological Reports, 2023
Cytokinins (CTKs) are a diverse collection of evolutionarily conserved adenine‐derived signaling molecules classically studied as phytohormones; however, their roles and production have been less studied in mammalian systems.
Stephanie W. Tobin, Dev Seneviratne, Lorna Phan, Mark Seegobin, Alexander L. Rico, Beth Westby, Anna Kisiala, Sanela Martic, Craig R. Brunetti, R. J. Neil Emery   +9 more
doaj   +1 more source

Editorial: Myokines, Adipokines, Cytokines in Muscle Pathophysiology [PDF]

Frontiers in Physiology, 2020
Individual striated muscle fibers communicate in both a paracrine and endocrine fashion and are also involved in the crosstalk with other tissues and organs such as the adipose tissue, immune system, liver, pancreas, bones, and brain (Delezie andHandschin, 2018).
Valentina Di Felice, Dario Coletti, Dario Coletti, Dario Coletti, Marilia Seelaender   +4 more
openaire   +3 more sources

Exercise in the cold causes greater irisin release but may not be enough for adropin

Chinese Journal of Physiology, 2021
When irisin and adropin were discovered, it was popularly hoped that they would become therapies for metabolic disorders that threaten global health. However, contradictory results have been reported in the subsequent period.
Suleyman Ulupinar, Serhat Ozbay, Cebrail Gencoglu, Konca Altinkaynak, Engin Sebin, Burak Oymak   +5 more
doaj   +1 more source

Mitochondria Homeostasis and Oxidant/Antioxidant Balance in Skeletal Muscle—Do Myokines Play a Role?

Antioxidants, 2021
Mitochondria are the cellular powerhouses that generate adenosine triphosphate (ATP) to substantiate various biochemical activities. Instead of being a static intracellular structure, they are dynamic organelles that perform constant structural and ...
Brian Pak Shing Pang, Wing Suen Chan, Chi Bun Chan   +2 more
doaj   +1 more source

Skeletal muscle: novel and intriguing characteristics as a secretory organ [PDF]

BioDiscovery, 2013
Growing evidence has shown that skeletal muscle secretes several bioactive proteins from within the cell into extracellular fluid. The secretion of several proteins, whose levels increase in response to exercise, can regulate the functions of several ...
Wataru Aoi, Kunihiro Sakuma
doaj   +3 more sources