Results 41 to 50 of about 6,457 (246)
Chinese Journal of Physiology, 2020 The aim of this study is to investigate the acute and chronic effects of aerobic training performed indoors and outdoors on irisin, adropin, and cholesterol levels in winter. Thirty-two healthy males participated in this study.
Serhat Ozbay +3 more
doaj +1 more source
Myokines: Do they really exist?
The Journal of Physical Fitness and Sports Medicine, 2012 Skeletal muscle has only recently been considered a secretory organ. Muscle-derived proteins are now termed myokines. Until date, about 20 proteins known as cytokines, growth factors, and adipokines have been reported as myokines. However, only a few studies have been able to demonstrate secretion from the skeletal muscle. Furthermore, many reports are
Mayumi Takagi +2 more
openaire +4 more sources
Myokines: Crosstalk and Consequences on Liver Physiopathology
Nutrients, 2023 Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease mainly characterized by the hepatic accumulation of lipid inducing a deregulation of β-oxidation. Its advanced form is non-alcoholic steatohepatitis (NASH), which, in addition to lipid accumulation, induces hepatocellular damage, oxidative stress and fibrosis that can progress to ...
Aurore Dumond Bourie +3 more
openaire +2 more sources
The Controversial Role of Irisin in Clinical Management of Coronary Heart Disease
Frontiers in Endocrinology, 2021 Irisin, a PGC1α-dependent myokine, was once believed to have beneficial effects induced by exercise. Since its first discovery of adipose browning in 2012, multiple studies have been trying to explore the metabolic functions of irisin, such as glucose ...
Wen-Lu Ou-Yang +10 more
doaj +1 more source
Lecithin Alleviates Memory Deficits and Muscle Attenuation in Chinese Older Adults and SAMP8 Mice
Advanced Science, EarlyView.This study opens a new avenue for safeguarding cognition and muscle health, averting disability in older age, and treating age‐related pathologies through lecithin supplementation. It serves as a promising nonpharmacological intervention for the crosstalk of muscle and cognition.
Xianyun Wang +16 more
wiley +1 more source
Epinephrine stimulates CXCL1 IL‐1α, IL‐6 secretion in isolated mouse limb muscle
Physiological Reports, 2017 Catecholamines stimulate interleukin‐6 (IL‐6) secretion in skeletal muscles. However, whether other cytokines are secreted is currently unknown. Skeletal muscle ex vivo preparations commonly used to study cytokine secretion have dealt with limitations ...
Alex J. Mattingly +2 more
doaj +1 more source
Genetic variation of putative myokine signaling is dominated by biological sex and sex hormones
eLife, 2022 Skeletal muscle plays an integral role in coordinating physiological homeostasis, where signaling to other tissues via myokines allows for coordination of complex processes.
Leandro M Velez +6 more
doaj +1 more source
Advanced Science, EarlyView.sEVs have a critical role in orchestrating interorgan crosstalk and mediating exercise‐induced therapeutic effects. Lin et al. demonstrates that sEVs miR‐17/20a‐5p mediates the muscle‐brain crosstalk and emphasizes the central role of mTOR signaling in executing molecular programs that can protect brain health in response to exercise. Abstract Physical
Huawei Lin +21 more
wiley +1 more source
Irisin Serum Levels and Skeletal Muscle Assessment in a Cohort of Charcot-Marie-Tooth Patients
Frontiers in Endocrinology, 2022 BackgroundCharcot-Marie-Tooth (CMT) indicates a group of inherited polyneuropathies whose clinical phenotypes primarily include progressive distal weakness and muscle atrophy.
Graziana Colaianni +13 more
doaj +1 more source
Advanced Science, EarlyView.Irisin is a crucial plasma biomarker and promising therapeutic target that reflects disease severity, pulmonary vascular remodeling status and clinical outcome in patients with pulmonary arterial hypertension (PAH). As a novel protective factor, irisin is downregulated in PAH. By ubiquitination, irisin promotes Enolase 1 degradation and suppresses cell
Na Sun +15 more
wiley +1 more source