Results 71 to 80 of about 6,457 (246)

Profiling of adenine‐derived signaling molecules, cytokinins, in myotubes reveals fluctuations in response to lipopolysaccharide‐induced cell stress

Physiological Reports, 2023
Cytokinins (CTKs) are a diverse collection of evolutionarily conserved adenine‐derived signaling molecules classically studied as phytohormones; however, their roles and production have been less studied in mammalian systems.
Stephanie W. Tobin, Dev Seneviratne, Lorna Phan, Mark Seegobin, Alexander L. Rico, Beth Westby, Anna Kisiala, Sanela Martic, Craig R. Brunetti, R. J. Neil Emery   +9 more
doaj   +1 more source

Effect of human myoblasts on tenogenic progression in 2D and 3D culture models

Journal of Anatomy, EarlyView.
We investigated whether factors released from muscle derived myogenic cells enhance tenogenic progressions of human tendon derived cells using two‐dimensional (2D) culture model and a three‐dimensional (3D)‐engineered tendon construct culture model.
Yoshifumi Tsuchiya, Ching‐Yan Chloé Yeung, Rene B. Svensson, Michael Kjaer   +3 more
wiley   +1 more source

FGF21 as Modulator of Metabolism in Health and Disease

Frontiers in Physiology, 2019
Fibroblast growth factor 21 (FGF21) is a hormone that regulates important metabolic pathways. FGF21 is expressed in several metabolically active organs and interacts with different tissues.
Caterina Tezze, Caterina Tezze, Vanina Romanello, Vanina Romanello, Marco Sandri, Marco Sandri, Marco Sandri, Marco Sandri   +7 more
doaj   +1 more source

Cholecystokinin: Clinical aspects of the new biology

Journal of Internal Medicine, EarlyView.
Abstract Cholecystokinin (CCK) is a classic gut hormone that has been known for almost a century to regulate gallbladder emptying, pancreatic enzyme secretion, and gastrointestinal motor activity. In 1968, the CCK structure was identified by Viktor Mutt and Erik Jorpes from porcine gut extracts as a peptide of 33 amino acid residues.
Jens F. Rehfeld
wiley   +1 more source

Physical exercise associated with NO production: Signaling pathways and significance in health and disease

Frontiers in Cell and Developmental Biology, 2015
Here we review available data on nitric oxide (NO)-mediated signaling in skeletal muscle during physical exercise. Nitric oxide modulates skeletal myocyte function, hormone regulation, and local microcirculation.
Elena Yu Dyakova, Leonid V Kapilevich, Victor G Shylko, Sergey V Popov, Yana eAnfinogenova   +4 more
doaj   +1 more source

Histidine‐Containing Dipeptides in Obesity and Cardiometabolic Health: A Systematic Scoping Review

Obesity Reviews, EarlyView.
ABSTRACT Background Histidine‐containing dipeptides (HCDs) have been reported to have anti‐inflammatory and antidiabetic properties. Yet, no previous reviews have examined the impact of HCDs on Type 2 diabetes (T2D) risk factors (e.g., obesity) and progression (e.g., microvascular and macrovascular complications).
Saeede Saadati, Robel Hussen Kabthymer, Giancarlo Aldini, Thilini R. Thrimawithana, Julie E. Stevens, Kathy Ngyuen, Arshad Majid, Simon M. Bell, Jack Feehan, Aya Mousa, Barbora de Courten   +10 more
wiley   +1 more source

Metabolic Health—The Role of Adipo-Myokines [PDF]

International Journal of Molecular Sciences, 2019
Obesity is now a worldwide epidemic. In recent years, different phenotypes of obesity, ranging from metabolically healthy normal weight to metabolically unhealthy obese, were described. Although there is no standardized definition for these phenotypes or for metabolic health, the influence of lifestyle and early-life factors is undisputed.
Nina Ferrari, Christine Graf
openaire   +3 more sources

Irisin levels are not affected by physical activity in patients with anorexia nervosa

Frontiers in Endocrinology, 2014
Irisin was recently identified as muscle-derived hormone that increases energy expenditure. Studies in normal weight and obese subjects reported an increased irisin expression following physical activity, although inconsistent results were observed ...
Tobias eHofmann, Ulf eElbelt, Ulf eElbelt, Anne eAhnis, Peter eKobelt, Matthias eRose, Andreas eStengel   +6 more
doaj   +1 more source

Immune system benefits of pulmonary rehabilitation in chronic obstructive pulmonary disease

Experimental Physiology, EarlyView.
Abstract Chronic obstructive pulmonary disease (COPD) is a respiratory disease characterized by pulmonary and systemic inflammation. Inflammatory mediators show relationships with shortness of breath, exercise intolerance and health related quality of life. Pulmonary rehabilitation (PR), a comprehensive education and exercise training programme, is the
Asghar Abbasi, David Wang, William W. Stringer, Richard Casaburi, Harry B. Rossiter   +4 more
wiley   +1 more source

Aberrant Myokine Signaling in Congenital Myotonic Dystrophy [PDF]

Cell Reports, 2017
Myotonic dystrophy types 1 (DM1) and 2 (DM2) are dominantly inherited neuromuscular disorders caused by a toxic gain of function of expanded CUG and CCUG repeats, respectively. Although both disorders are clinically similar, congenital myotonic dystrophy (CDM), a severe DM form, is found only in DM1. CDM is also characterized by muscle fiber immaturity
Department of Neurology, Osaka University Graduate School of Medicine, Suita, Osaka 565-0871, Japan ( host institution ), Nakamori, Masayuki ( author ), Hamanaka, Kohei ( author ), Thomas, James D. ( UF author ), Wang, Eric T. ( UF author ), Hayashi, Yukiko K. ( author ), Takahashi, Masanori P. ( author ), Swanson, Maurice S. ( UF author ), Nishino, Ichizo ( author ), Mochizuki, Hideki ( author )   +9 more
openaire   +5 more sources