Results 181 to 190 of about 380,707 (403)
Advanced Science, EarlyView.By integrating biomechanical and epigenetic cues, the evolutionarily conserved TPM1 super‐enhancer drives myogenesis via TEAD4‐mediated chromatin looping. This mechanism produces species‐specific outputs (linear TPM1 mRNA in mice and CircTPM1 in bovine) that activate PI3K/AKT mechanotransduction and the MYH10/MYL3 axis to execute cytoskeletal ...
Ruimen Zhang +27 more
wiley +1 more source
Effect of Catechins on the Physicochemical, Structural and Gel Properties of Myosin in Tilapia
Shipin gongye ke-jiThis study investigated the influence of different mass concentrations of catechin (0~1.00 mg/mL) on the physicochemical characteristics, structures, and gel properties of myosin, through analyses of the turbidity, particle size, Zeta potential, surface ...
Yuyu HANG, Yang ZHANG, Du TAN, Yaqin HU
doaj +1 more source
Congenital Contracture Syndrome Caused by Mutation in Embryonic Myosin Heavy Chain Characterized by Significant Changes in Adult Muscle Contractility [PDF]
, 2010 Alice Ward +3 more
openalex +1 more source
A stochastic model for the stepwise motion in actomyosin dynamics
, 2003 A jump-diffusion process is proposed to describe the displacements performed by single myosin heads along actin filaments during the rising phases.
Buonocore, A. +3 more
core
Advanced Science, EarlyView.A bioorthogonal rhodamine/PEG crosslinking strategy is introduced to engineer dense collagen hydrogels with high mechanical resilience and cytocompatibility. Integration with wet‐spinning enables the fabrication of uniaxially aligned, cell‐laden collagen filaments that activate mechanotransductive signaling and support functional muscle regeneration in
JuYeon Kim +4 more
wiley +1 more source
Structural and Biochemical Kinetics of Cardiac Myosin and its Perturbation by a Known Heart Failure Drug Investigated with Transient Time-Resolved FRET [PDF]
, 2016 John A. Rohde +2 more
openalex +1 more source
Advanced Science, EarlyView.This study presents an impedance‐based single‐cell profiling platform that quantifies the electrical and mechanical properties of neutrophils across in vitro, in vivo, and clinical samples. The approach reveals distinct biophysical alterations associated with type 2 diabetes (T2DM) and cardiovascular complications, suggesting its potential utility for ...
Linwei He +13 more
wiley +1 more source
HUWE1 in Skeletal Muscle Prevents Muscle Fatigue via Maintaining Iron and Calcium Homeostasis
Advanced Science, EarlyView.This study investigates the impact of iron homeostasis on exercise. Loss of the HECT domain‐containing ubiquitin ligase E3 (HUWE1) in skeletal muscle restrains the exercise performance in mice with downregulated ferroportin expression leading to iron overload, which is ameliorated by dietary iron restriction.
Huike Jiao +10 more
wiley +1 more source
Mitochondrial Adaptation to Mechanical Stress in Cardiac Ageing and Disease
Advanced Science, EarlyView.Mechanical forces shape the heart's energy factories. This review explores how mitochondria in cardiac cells sense and respond to biomechanical stress, altering their structure, positioning, and metabolism. By linking mechanical cues to mitochondrial adaptation, the article highlights pathways driving heart disease and points to new strategies for ...
Aishwarya Prakash, Thomas Iskratsch
wiley +1 more source