Results 11 to 20 of about 380,707 (403)
Myosin II filament dynamics in actin networks revealed with interferometric scattering microscopy [PDF]
, 2020 The plasma membrane and the underlying cytoskeletal cortex constitute active platforms for a variety of cellular processes. Recent work has shown that the remodeling acto-myosin network modifies local membrane organization, but the molecular details are ...
Fineberg, A. +7 more
core +1 more source
Stratification relieves constraints from steric hindrance in the generation of compact acto-myosin asters at the membrane cortex [PDF]
, 2020 Recent in-vivo studies have revealed that several membrane proteins are driven to form nanoclusters by active contractile flows arising from F-actin and myosin at the cortex. The mechanism of clustering was shown to be arising from the dynamic patterning
Bhat, Abrar +5 more
core +3 more sources
Secondary Structure of the Novel Myosin Binding Domain WYR and Implications within Myosin Structure
Biology, 2021 Structural changes in the myosin II light meromyosin (LMM) that influence thick filament mechanical properties and muscle function are modulated by LMM-binding proteins.
Lynda M. Menard +2 more
doaj +1 more source
Biomolecules, 2020 Cardiovascular diseases are one of the leading causes of death in developing countries, generally originating as coronary artery disease (CAD) or hypertension. In later stages, many CAD patients develop left ventricle dysfunction (LVD).
Surendra Kumar +2 more
doaj +1 more source
Expression of non-muscle type myosin heavy polypeptide 9 (MYH9) in mammalian cells
European Journal of Histochemistry, 2009 Myosin is a functional protein associated with cellular movement, cell division, muscle contraction and other functions. Members of the myosin super-family are distinguished from the myosin heavy chains that play crucial roles in cellular processes ...
T Takubo +6 more
doaj +1 more source
eLife, 2020 Collective cell migration is central to many developmental and pathological processes. However, the mechanisms that keep cell collectives together and coordinate movement of multiple cells are poorly understood. Using the Drosophila border cell migration
Yujun Chen +9 more
doaj +1 more source
Myosin filament-based regulation of the dynamics of contraction in heart muscle
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance Cardiovascular disease continues to be the leading cause of death worldwide, and is frequently associated with heart failure. Efforts to develop better therapeutics for heart failure have been held back by limited understanding of the normal
E. Brunello +6 more
semanticscholar +1 more source
Characterization and analysis of myosin gene family in the whitefly (Bemisia tabaci)
AIMS Molecular Science, 2022 Myosin is an actin-based motor protein that widely exists in muscle tissue and non-muscle tissue, and myosin of a diverse subfamily has obvious differences in structure and cell function.
Kui Wang +7 more
doaj +1 more source
Diverse integrin adhesion stoichiometries caused by varied actomyosin activity [PDF]
Open Biology, 2017 Cells in an organism are subjected to numerous sources of external and internal forces, and are able to sense and respond to these forces. Integrin-mediated adhesion links the extracellular matrix outside cells to the cytoskeleton inside, and ...
Natalia A. Bulgakova +2 more
doaj +1 more source
The formin inhibitor SMIFH2 inhibits members of the myosin superfamily
bioRxiv, 2020 The small molecular inhibitor of formin FH2 domains, SMIFH2, is widely used in cell biological studies. It was selected in a chemical screen as a compound inhibiting formin-driven actin polymerization in vitro, but not polymerization of pure actin, and ...
Yukako Nishimura +7 more
semanticscholar +1 more source