Single molecule mechanics resolves the earliest events in force generation by cardiac myosin
eLife, 2019 Key steps of cardiac mechanochemistry, including the force-generating working stroke and the release of phosphate (Pi), occur rapidly after myosin-actin attachment.
Michael S Woody +4 more
doaj +1 more source
Mitochondrial transport in neurons and evidence for its involvement in acute neurological disorders
Frontiers in Neuroscience, 2023 Ensuring mitochondrial quality is essential for maintaining neuronal homeostasis, and mitochondrial transport plays a vital role in mitochondrial quality control.
Dengfeng Lu +8 more
doaj +1 more source
Type-I myosins promote actin polymerization to drive membrane bending in endocytosis
eLife, 2019 Clathrin-mediated endocytosis in budding yeast requires the formation of a dynamic actin network that produces the force to invaginate the plasma membrane against the intracellular turgor pressure.
Hetty E Manenschijn +5 more
doaj +1 more source
Mechanosensing in myosin filament solves a 60 years old conflict in skeletal muscle modeling between high power output and slow rise in tension [PDF]
, 2016 Almost 60 years ago Andrew Huxley with his seminal paper \cite{Huxley1957} laid the foundation of modern muscle modeling, linking chemical events to mechanical performance.
Marcucci, Lorenzo, Reggiani, Carlo
core +3 more sources
Foods, 2022 To further prove the advantages of microwave-assisted water bath heating (MWH) in low-value fish processing, the effects of different heating methods (two heating stage method, high temperature section respectively using MWH1, MWH2, MWH3, WH—water ...
Haihua Cong +4 more
doaj +1 more source
Prdm1 (Blimp-1) and the Expression of Fast and Slow Myosin Heavy Chain Isoforms during Avian Myogenesis In Vitro [PDF]
, 2010 BACKGROUND. Multiple types of fast and slow skeletal muscle fibers form during early embryogenesis in vertebrates. In zebrafish, formation of the earliest slow myofibers in fin muscles requires expression of the zinc-finger transcriptional repressor ...
Ardelt, Magdalena +3 more
core +4 more sources
Life, 2023 Asymmetry plays a major role in biology at all scales. This can be seen in the helix of DNA, the fact that the human heart is on the left side, or that most people use their right hand.
Alexander Egoyan +4 more
doaj +1 more source
Cardiac myosin binding protein-C phosphorylation regulates the super-relaxed state of myosin
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance Cardiac myosin binding protein-C (cMyBP-C) is a sarcomeric protein closely linked to cardiac contractility. Importantly, although the phosphorylation status of cMyBP-C regulates the force and rate of cardiac contraction, the exact molecular ...
James W. McNamara +2 more
semanticscholar +1 more source
Model for processive movement of myosin V and myosin VI
, 2003 Myosin V and myosin VI are two classes of two-headed molecular motors of the myosin superfamily that move processively along helical actin filaments in opposite directions. Here we present a hand-over-hand model for their processive movements.
Dou, Shuo-Xing, Wang, Peng-Ye, Xie, Ping
core +1 more source
Dynamics of myosin, microtubules, and Kinesin-6 at the cortex during cytokinesis in Drosophila S2 cells [PDF]
, 2009 © The Authors, 2009 . This article is distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. The definitive version was published in Journal of Cell Biology 186 (2009): 727-738, doi:10.1083/jcb ...
Griffis, Eric R. +2 more
core +5 more sources