Results 41 to 50 of about 159,767 (320)
Uncoupling apical constriction from tissue invagination
eLife, 2017 Apical constriction is a widely utilized cell shape change linked to folding, bending and invagination of polarized epithelia. It remains unclear how apical constriction is regulated spatiotemporally during tissue invagination and how this cellular ...
SeYeon Chung +2 more
doaj +1 more source
Diverse integrin adhesion stoichiometries caused by varied actomyosin activity [PDF]
Open Biology, 2017 Cells in an organism are subjected to numerous sources of external and internal forces, and are able to sense and respond to these forces. Integrin-mediated adhesion links the extracellular matrix outside cells to the cytoskeleton inside, and ...
Natalia A. Bulgakova +2 more
doaj +1 more source
Twirling of actin by myosins II and V observed via polarized TIRF in a modified gliding assay [PDF]
, 2008 The force generated between actin and myosin acts predominantly along the direction of the actin filament, resulting in relative sliding of the thick and thin filaments in muscle or transport of myosin cargos along actin tracks. Previous studies have also detected lateral forces or torques that are generated between actin and myosin, but the origin and
arxiv +1 more source
ATP-induced reconfiguration of the micro-viscoelasticity of cardiac and skeletal myosin solutions [PDF]
arXiv, 2022 We study the high-frequency micro-mechanical response of suspensions composed by cardiac and skeletal muscle myosin by optical trapping interferometry. We observe that in low ionic strength solutions upon the addition of magnesium adenosine triphosphate (\ch{MgATP^2-}), myosin suspensions radically change their micro-mechanics properties, generating a ...
arxiv
Spontaneous sarcomere dynamics [PDF]
Chaos 20, 0451222, (2010), 2012 Sarcomeres are the basic force generating units of striated muscles and consist of an interdigitating arrangement of actin and myosin filaments. While muscle contraction is usually triggered by neural signals, which eventually set myosin motors into motion, isolated sarcomeres can oscillate spontaneously between a contracted and a relaxed state.
arxiv +1 more source
Biomédica: revista del Instituto Nacional de Salud, 2002 Se construyó una genoteca de ADNc representativa de los estadios asexuales de Plasmodium falciparum, en el vector lZipLox. Esta genoteca (de la cepa colombiana FCB2) y otra genoteca construida en lZAP II (de la cepa Dd2), se rastrearon en busca de genes ...
Dary L. Mendoza, Moisés Wasserman
doaj +1 more source
Cooperation of myosin II in muscle contraction through nonlinear elasticity [PDF]
arXiv, 2023 Myosin II plays a pivotal role in muscle contraction by generating force through the cooperative action of multiple motors on actin filaments. In this study, we integrate the nonlinear elasticity of the neck linker in individual myosin II and comprehensively investigate the evolution of cooperativity and dynamics at {\it microstate} and {\it mesostate}
arxiv
Czech Journal of Food Sciences, 2009 Phenolic compounds were extracted from bearberry (Arctostaphylos uva-ursi L. Sprengel) leaves into 95% (v/v) ethanol. The tannin constituents were separated from the crude extract using Sephadex LH-20 column chromatography with 95% (v/v) ethanol and 50% (
Ryszard Amarowicz +2 more
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Biomolecules, 2020 Cardiovascular diseases are one of the leading causes of death in developing countries, generally originating as coronary artery disease (CAD) or hypertension. In later stages, many CAD patients develop left ventricle dysfunction (LVD).
Surendra Kumar +2 more
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Secondary Structure of the Novel Myosin Binding Domain WYR and Implications within Myosin Structure
Biology, 2021 Structural changes in the myosin II light meromyosin (LMM) that influence thick filament mechanical properties and muscle function are modulated by LMM-binding proteins.
Lynda M. Menard +2 more
doaj +1 more source