Results 71 to 80 of about 159,767 (320)

Zebrafish as a Model for the Study of Live in vivo Processive Transport in Neurons

Frontiers in Cell and Developmental Biology, 2019
Motor proteins are responsible for transport of vesicles and organelles within the cell cytoplasm. They interact with the actin cytoskeleton and with microtubules to ensure communication and supply throughout the cell.
Valérie Bercier, Valérie Bercier, Marion Rosello, Filippo Del Bene, Céline Revenu   +4 more
doaj   +1 more source

From Mechanoelectric Conversion to Tissue Regeneration: Translational Progress in Piezoelectric Materials

Advanced Materials, EarlyView.
This review highlights recent progress in piezoelectric materials for regenerative medicine, emphasizing their ability to convert mechanical stimuli into bioelectric signals that promote tissue repair. Key discussions cover the intrinsic piezoelectric properties of biological tissues, co‐stimulation cellular mechanisms for tissue regeneration, and ...
Xinyu Wang, Sílvio Terra Stefanello, Victor Shahin, Yun Qian   +3 more
wiley   +1 more source

Hydrogel‐Mediated Preservation of Live Tumor Explants for Drug Development in Peritoneal Metastases

Advanced Materials, EarlyView.
This study presents a hyaluronan‐based hydrogel platform preserving the native tumor microenvironment (morphology, tissue composition, histology) of patient‐derived explants from peritoneal metastases, enabling clinically relevant drug screening. Hydrogel properties such as stiffness and degradation are crucial for longer‐term histoculture.
Kenny Zhuoran Wu, Rockie Haiyao Ding, Zixuan Zhao, Clara Yieh Lin Chong, Ruochii You, Hengjia Zhou, Dong Hua Seah, Wei Qiang Leow, Hong Kit Lim, Sukanya Shyamasundar, Kanishka Fernando, Fathima Farzana Kuthubudeen, Gillian Ng, Chor Yong Tay, Narayanan Gopalakrishna Iyer, Chin‐Ann Johnny Ong, Eliza Li Shan Fong   +16 more
wiley   +1 more source

Biomimetic Dynamics of Nanoscale Groove and Ridge Topography for Stem Cell Regulation

Advanced Materials, EarlyView.
Dynamic nanoscale groove‐ridge structures are engineered by flexibly conjugating RGD‐magnetic nanoparticles to nanogroove templates with variable groove widths at the molecular scale. Magnetic control enables cyclic switching between nanoscale groove and ridge states that modulates ligand accessibility of cellular integrins.
Hyunsik Hong, Dahee Kim, Hwapyung Jung, Seongyeol Kim, Sunhong Min, Chowon Kim, Kanghyeon Kim, Hyunji Rha, Heemin Kang   +8 more
wiley   +1 more source

Determination of the Maximum Velocity of Filaments in the in vitro Motility Assay

Frontiers in Physiology, 2019
The in vitro motility assay (IVMA) is a powerful tool commonly used in basic muscle research and for drug screenings with the aim to find treatment options for neuromuscular disorders.
Nasrin Bopp, Nasrin Bopp, Lisa-Mareike Scheid, Rainer H. A. Fink, Karl Rohr   +4 more
doaj   +1 more source

Myosin XVI in the Nervous System

Cells, 2020
The myosin family is a large inventory of actin-associated motor proteins that participate in a diverse array of cellular functions. Several myosin classes are expressed in neural cells and play important roles in neural functioning.
Elek Telek, András Kengyel, Beáta Bugyi   +2 more
doaj   +1 more source

De Novo Design of Integrin α5β1 Modulating Proteins to Enhance Biomaterial Properties

Advanced Materials, EarlyView.
NeoNectins are de novo‐designed miniproteins that selectively bind and stabilize the extended open form of integrin α5β1. When grafted onto biomaterials including hydrogel and titanium, they promote cell attachment and spreading in vitro and promoting tissue integration and bone growth in animal models, demonstrating broad potential for regenerative ...
Xinru Wang, Jordi Guillem‐Marti, Saurav Kumar, David S. Lee, Daniel Cabrerizo‐Aguado, Rachel Werther, Kevin Alexander Estrada Alamo, Yan Ting Zhao, Adam Nguyen, Irina Kopyeva, Buwei Huang, Jing Li, Yuxin Hao, Xinting Li, Aritza Brizuela‐Velasco, Analisa Murray, Stacey Gerben, Anindya Roy, Cole A. DeForest, Timothy Springer, Hannele Ruohola‐Baker, Jonathan A. Cooper, Melody G. Campbell, Jose Maria Manero, Maria‐Pau Ginebra, David Baker   +25 more
wiley   +1 more source

An expanded role of the SNARE-containing regulon as it relates to the defense process that Glycine max has to Heterodera glycines

Journal of Plant Interactions, 2019
The defense regulon has been defined genetically in Arabidopsis thaliana to involve the syntaxin PENETRATION1 (PEN1), the secreted glucosidase (PEN2) and an ATP-binding cassette (ABC) transporter (PEN3).
Hannah W. Austin, Brant T. McNeece, Keshav Sharma, Prakash M. Niraula, Katherine S. Lawrence, Vincent P. Klink   +5 more
doaj   +1 more source

Bioinspired, Rapidly Responsive Magnetically Tunable Stiffness Metamaterials

Advanced Materials, EarlyView.
A 3D array of magnetoactive mechanical metamaterials enables rapid and reversible stiffness modulation under external magnetic fields. By adjusting field direction and intensity, the system exhibits diverse deformation modes and tunable modulus. This fast‐responding mechanical metamaterial offers real‐time adaptability for advanced reconfigurable and ...
Gooyoon Chung, Huy Le Quang, Jung Hyun Kim, Jeongmin Yoo, Seung Kwon Seol, Yoonseok Park   +5 more
wiley   +1 more source

Sliding Mechanism for Actin Myosin System [PDF]

INFORMATION, VOL.6 (2003)187-196, 2003
Based on the Stochastic Inclined Rods Model (SIRM) proposed by H. Matsuura and M. Nakano, we study the microscopic motion of actin myosin system including the motion of the G-actin. Our model is composed of an inclined spring (rod), a myosin head, a myosin filament and G-actins.
arxiv