Results 91 to 100 of about 29,584 (174)
ABSTRACT Aim Unlike humans, brown bears (Ursus arctos) uniquely preserve skeletal muscle mass and function during months of hibernation despite prolonged fasting and inactivity. We investigated how mitochondrial energetics respond in skeletal muscle to support this remarkable resilience.
Audrey Bergouignan +13 more
wiley +1 more source
DNA methylation as a predictor of pituitary neuroendocrine tumour behaviour: A systematic review
Abstract Pituitary neuroendocrine tumours (PitNETs) range from slow‐growing to highly aggressive tumours; however, traditional prognostic markers often fail to predict clinical outcomes reliably. DNA methylation has recently emerged as a promising biomarker for assessing tumour behaviour. This systematic review evaluates its predictive value in PitNETs.
Romy van der Groef +3 more
wiley +1 more source
Myosin XI Interacting with a RabE GTPase Is Required for Polarized Growth [PDF]
AbstractThe fundamental eukaryotic process of intracellular trafficking requires the interconnected activity of molecular motors trafficking vesicular cargo within a dynamic cytoskeletal network. However, in plants, few mechanistic details are known about how molecular motors associate with their secretory cargo to support the ubiquitous processes of ...
Orr, Robert G. +9 more
openaire +1 more source
Contraction of cross-linked actomyosin bundles
Cross-linked actomyosin bundles retract when severed in vivo by laser ablation, or when isolated from the cell and micromanipulated in vitro in the presence of ATP.
Bonnet I +12 more
core +1 more source
Targeting Arterial Dysfunction in Cardiovascular Disease Using Stem Cell‐Based Therapies
Graphical presentation of stem cell‐based therapies for arterial dysfunction, endothelial repair and regeneration strategies. SMC, smooth muscle cell. ABSTRACT Arterial regeneration represents a critical frontier in cardiovascular medicine, as progressive endothelial dysfunction, maladaptive vascular smooth muscle cell (SMC) plasticity, and chronic ...
Yun‐Yu Ma, Shu‐Yao Zhu, Yi Song
wiley +1 more source
Quantitative analysis of the root posture of Arabidopsis thaliana mutants with wavy roots
Plant postures are affected by environmental stimuli. When the gravitational direction changes, the Arabidopsis thaliana mutants myosin xif xik (xif xik) and atp-binding cassette b19 (abcb19) exhibit aberrantly enhanced organ bending.
Hiroki Yagi +2 more
doaj +1 more source
PKCα and CPI-17 expression and spatial-temporal distribution with activation in pig stomach antrum and fundus [PDF]
Smooth muscle contraction is a complicated process coordinated by contractile, regulatory and cytoskeletal proteins. The force generation depends on the phosphorylation of Myosin Regulatory Light Chain (MLC20). Myosin Light Chain Kinase (MLCK) and Myosin
Zhang, Yu
core +1 more source
High light exposure triggers an epidermis‐specific remodeling of mitochondria and ER in Arabidopsis, driven by chloroplast‐derived signals. Live‐cell imaging shows that HL rapidly suppresses mitochondrial motility, followed by fusion‐driven elongation and ER cisternal expansion.
Evan R. Angelos +12 more
wiley +1 more source
ORYZA SATIVA MYOSIN XI B controls pollen development by photoperiod-sensitive protein localizations
Myosins are actin-based motor proteins responsible for various motility and signal transduction. Only a small set of myosin classes is present inplants, and little is known about their functions. Here we showed how a rice myosin gene controlled pollen development by sensing changed environmental factors.
Jiang, S.-Y., Cai, M., Ramachandran, S.
openaire +2 more sources
Requirements for contractility in disordered cytoskeletal bundles
Actomyosin contractility is essential for biological force generation, and is well understood in highly organized structures such as striated muscle. Additionally, actomyosin bundles devoid of this organization are known to contract both in vivo and in ...
Aaron R Dinner +8 more
core +1 more source

