Results 81 to 90 of about 5,528 (166)
Advanced Science, Volume 13, Issue 33, 15 June 2026.This study investigates how CTCs survive varying shear stress during hematogenous metastasis. We uncover a self‐protection mechanism, by which non‐adherent CTCs adapt to high shearing milieu through accumulated cytoplasmic myosin‐mediated disruption of myosin‐actin binding, attenuating force transmission into chromatin to protect CTCs from shear ...
Cunyu Zhang +10 more
wiley +1 more source
Clinical and Translational Discovery, Volume 6, Issue 3, June 2026.•Single‐cell/spatial multi‐omics identify four VSMC phenotypic states in TAA progression. •KLF4 as master hub (TGF‐β/TNF‐α/mechanical stress) orchestrating chromatin remodelling. •Pseudotime trajectories mapping contractile phenotypes towards osteogenic (RUNX2/SOX9) and inflammatory (TNF‐α/IL‐6) fates within spatial medial niches. •cfDNA biomarkers and
Zehua Shao +6 more
wiley +1 more source
, 2014 A-F, Fluorescence intensity (arbitrary units) of the TMV-GFP infection sites analyzed in Figure 1. Fluorescence intensity was quantified using ImageJ software and normalized to the area of the same infection sites. Except for myosin XI-2 tails (Figure 3D)
Martin Di Donato (645715) +3 more
core +1 more source
International Journal of Nanomedicine, 2023 Yu-Cheng Zhang,1,2,* Yu-Xia Yang,2,3,* Yu Liu,4 Xi-Jian Liu,5 Ji-Hang Dai,2 Rang-Shan Gao,2 Yang-Yang Hu,2 Wen-Yong Fei2 1Clinical Medical College, Dalian Medical University, Dalian, 116044, People’s Republic of China; 2Department of Orthopedics ...
Zhang YC +7 more
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Inhibition of myosin XI-2 disrupts the normal subcellular localization of expressed 126k:GFP.
, 2014 A, co-expression of 126k:GFP together with RFP. The 126k:GFP accumulates in large aggregates. B, co-expression of 126k:GFP together with myosin XI-2 tails. 126k:GFP is dispersed into numerous small aggregates.
Martin Di Donato (645715) +3 more
core +1 more source
MedComm, Volume 7, Issue 6, June 2026.This graphical abstract delineates noncanonical protein secretion systems across eukaryotes and prokaryotes. Eukaryotic UcPS covers four ER–Golgi bypass pathways, enabling rapid leaderless protein export via direct transmembrane translocation or vesicle‐mediated release.
Qiyuan Yang +8 more
wiley +1 more source
The FASEB Journal, Volume 40, Issue 10, 31 May 2026.MFAP4 deficiency exacerbates heatstroke outcomes, accelerating hyperthermia, delaying recovery, reducing survival, and worsening cardiac injury. Conversely, MFAP4 overexpression enhances cellular thermoresistance. MFAP4 orchestrates transcriptional reprogramming in response to HS.
LiJun Fan +8 more
wiley +1 more source
Expression, Splicing, and Evolution of the Myosin Gene Family in Plants [PDF]
, 2011 Plants possess two myosin classes, VIII and XI. The myosins XI are implicated in organelle transport, filamentous actin organization, and cell and plant growth.
Sergei A. Filichkin +7 more
core +1 more source
A Novel PPP1R12A Splice‐Site Variant Identified in a Female Fetus With Perineal Hamartoma
Prenatal Diagnosis, EarlyView.
Shiyu Chen, Xi Tan
wiley +1 more source
Sensing and Filtering Environmental Fluctuations: The Case of Biomolecular Condensates in Plants
Advanced Science, Volume 13, Issue 27, 13 May 2026.The diversity of plant condensates reflects constraints of sessile organisms to coordinate postembryonic development with environmental adaptation. This review examines how plants employ condensates to integrate temperature, light, redox, and nutrient signals.
Panagiotis N. Moschou, Dorothee Staiger
wiley +1 more source