Results 61 to 70 of about 5,250 (139)

Divergent Atrial Transcriptomic Signatures in Diabetic and Nondiabetic Atrial Fibrillation

Journal of Arrhythmia, Volume 42, Issue 4, August 2026.
Diabetes alters the atrial transcriptome in atrial fibrillation, characterized by enhanced mitochondrial ATP synthesis, suppressed immune and inflammatory pathways, and distinct miRNA expression profiles, suggesting metabolic and epigenetic remodeling of the atrial substrate.
Kenshi Yoshimura, Yuya Kiriake, Hiroki Osanai, Mengyan Wei, Shinichiro Kume, Tatsuki Kurokawa, Masaki Morishima, Ryusuke Suzuki, Shinji Miyamoto, Katsushige Ono   +9 more
wiley   +1 more source

Myosin XI Interacting with a RabE GTPase Is Required for Polarized Growth [PDF]

, 2019
Abstract The fundamental eukaryotic process of intracellular trafficking requires the interconnected activity of molecular motors trafficking vesicular cargo within a dynamic cytoskeletal network. However, in plants, few mechanistic details are known about how molecular motors associate with their secretory cargo to ...
Orr, Robert G., Furt, Fabienne, Warner, Erin L., Agar, Erin M., Garbarino, Jennifer M., Cabral, Sarah E., Dubuke, Michelle L., Butt, Allison M., Munson, Mary, Vidali, Luis   +9 more
openaire   +1 more source

An Integrative Methylation‐Metabolism Gene Signature Defines Prognosis and Immunosuppressive Microenvironment in Prostate Cancer

Chemical Biology &Drug Design, Volume 108, Issue 1, July 2026.
This study developed a 6‐gene prognostic model integrating methylation and amino acid metabolism to predict PCa outcomes and reveal immunosuppressive TME. ABSTRACT The synergistic crosstalk between epigenetic dysregulation and metabolic reprogramming underlies to prostate cancer (PCa) development and treatment resistance, yet an integrated prognostic ...
Chao Zhang, Likun Liu, Kai Wu
wiley   +1 more source

An ER–microtubule bridge: Reticulon 17 links microtubules with ER network organisation in plants

The Plant Journal, Volume 127, Issue 1, July 2026.
Significance Statement Endoplasmic reticulum (ER) organisation underpins key processes in plant growth, secretion, and stress responses, yet how the ER connects to the cytoskeleton remains unclear. We identify Arabidopsis Reticulon 17 (RTN17) as an atypical reticulon that links the ER to microtubules and recruits the ER fusogen RHD3 to curved ER ...
Carmen Mata, Stefan Wojcik, Verena Kriechbaumer, Charlotte Pain   +3 more
wiley   +1 more source

Combining Porous Se@SiO2 Nanocomposites and dECM Enhances the Myogenic Differentiation of Adipose-Derived Stem Cells

International Journal of Nanomedicine, 2023
Yu-Cheng Zhang,1,2,* Yu-Xia Yang,2,3,* Yu Liu,4 Xi-Jian Liu,5 Ji-Hang Dai,2 Rang-Shan Gao,2 Yang-Yang Hu,2 Wen-Yong Fei2 1Clinical Medical College, Dalian Medical University, Dalian, 116044, People’s Republic of China; 2Department of Orthopedics ...
Zhang YC, Yang YX, Liu Y, Liu XJ, Dai JH, Gao RS, Hu YY, Fei WY   +7 more
doaj  

Mechanoadaptation via Myosin Cytoplasmic Redistribution Protects Circulating Tumor Cells From Shear‐induced Death During Hematogenous Dissemination

Advanced Science, Volume 13, Issue 33, 15 June 2026.
This study investigates how CTCs survive varying shear stress during hematogenous metastasis. We uncover a self‐protection mechanism, by which non‐adherent CTCs adapt to high shearing milieu through accumulated cytoplasmic myosin‐mediated disruption of myosin‐actin binding, attenuating force transmission into chromatin to protect CTCs from shear ...
Cunyu Zhang, Qianchun Wang, Keming Li, Guanshuo Hu, Ying Xin, Kai Tang, Bing Hu, Pengyu Du, Renwei Mao, Baohua Ji, Youhua Tan   +10 more
wiley   +1 more source

PEK14: A Kinesin‐4 Necessary for Male‐Derived Fertility in Arabidopsis thaliana

Cytoskeleton, Volume 83, Issue 6, Page 337-353, June 2026.
ABSTRACT Of the 61 kinesins annotated in Arabidopsis thaliana , many are still without assigned function. Here, we have screened an insertional mutant library of Arabidopsis pollen‐expressed kinesins for fertility defects. Insertional mutants for three kinesins showed a significant reduction in seed set.
Isabella N. Mendes, Norman R. Groves, Jessica Z. Li, Lily N. Thompson, Brian J. Smith, Aman Y. Husbands, Iris Meier   +6 more
wiley   +1 more source

Nuclear Entanglement: New Insights Into the Role of Cytoskeleton and Nucleoskeleton in Plant Nuclear Function

Cytoskeleton, Volume 83, Issue 6, Page 354-375, June 2026.
ABSTRACT Of the three types of cytoskeleton known in animals—actin, microtubules, and intermediate filaments—only actin and microtubules exist in plants. Both play important roles in cellular shaping, organelle movement, organization of the endomembrane system, and cell signaling.
Norman R. Groves, Katelyn Amstutz, Lily A. Schumacher, Iris Meier   +3 more
wiley   +1 more source

Making Two out of One: Kinesin Motors Driving Plant Cell Division

Cytoskeleton, Volume 83, Issue 6, Page 384-393, June 2026.
ABSTRACT The Kinesin superfamily of microtubule dependent motors is present in all eukaryotes. Not all of the subfamilies are represented in all kingdoms, and the ones that are do not always show conserved functions. Tight control of the cytoskeleton is essential for proper progression and completion of mitosis and cytokinesis, and key functions are ...
Choy Kriechbaum, Sabine Müller
wiley   +1 more source

Quantitative analysis of the root posture of Arabidopsis thaliana mutants with wavy roots

Quantitative Plant Biology
Plant postures are affected by environmental stimuli. When the gravitational direction changes, the Arabidopsis thaliana mutants myosin xif xik (xif xik) and atp-binding cassette b19 (abcb19) exhibit aberrantly enhanced organ bending.
Hiroki Yagi, Ikuko Hara-Nishimura, Haruko Ueda   +2 more
doaj   +1 more source