Results 61 to 70 of about 5,528 (166)

Expanded Phenotype Associated With an Intronic PPP1R12A Variant: A Case Report and Literature Review

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Autosomal dominant PPP1R12A‐related genitourinary and/or brain malformation syndrome is a recently described multisystem disorder caused by loss‐of‐function variants in the protein phosphatase 1 regulatory subunit 12a (PPP1R12A) gene. To date, 22 affected individuals have been reported with variable brain malformations and genitourinary ...
Emily M. Bland, Amber Nakar Weinstein, Eric C. Kao, Xiaonan Zhao, Monika Weisz‐Hubshman   +4 more
wiley   +1 more source

Exploitation of Engineered Light-Switchable Myosin XI for Nanotechnological Applications

For certain nanotechnological applications of the contractile proteins actin and myosin, e.g., in biosensing and network-based biocomputation, it would be desirable to temporarily switch on/off motile function in parts of nanostructured devices, e.g ...
Christoph R Meinecke (16892836), Pradheebha Surendiran (11943660), Sasha Zemsky (16892842), Aseem Salhotra (5523770), Paul V Ruijgrok (16892833), Zev Bryant (16892848), Frida W Lindberg (16892845), Till Korten (2128648), Alf Månsson (129987), Marko Ušaj (16892839), Heiner Linke (129982), Roman W. Lyttleton (1861552), Mohammad A Rahman (16892830)   +12 more
core   +4 more sources

Barley Ror1 encodes a class XI myosin required for mlo-based broad-spectrum resistance to the fungal powdery mildew pathogen [PDF]

, 2022
Loss-of-function alleles of plant MLO genes confer broad-spectrum resistance to powdery mildews in many eudicot and monocot species. Although barley (Hordeum vulgare) mlo mutants have been used in agriculture for more than 40 years, understanding of the ...
Baumgarten, Kira, Leissing, Franz, Drwiega, Katarzyna, Reinstädler, Anja, Acevedo‐Garcia, Johanna, Walden, Kim, Panstruga, Ralph, James, Geo Velikkakam, Freh, Matthias, Dong, Xue, Kwaaitaal, Mark   +10 more
core   +2 more sources

Interaction Between Actin and Microtubules During Plant Development

Cytoskeleton, EarlyView.
ABSTRACT The dynamic interaction between actin filaments (AFs) and microtubules (MTs) plays a crucial role in regulating key developmental and physiological processes in plant cells, particularly in the formation of specialized cell types with distinct shapes and functions, such as pollen tubes, trichomes, and leaf epidermal cells.
Zining Wu, Lidong Gao, M. Arif Ashraf, Qiong Nan   +3 more
wiley   +1 more source

PEK14: A Kinesin‐4 Necessary for Male‐Derived Fertility in Arabidopsis thaliana

Cytoskeleton, EarlyView.
ABSTRACT Of the 61 kinesins annotated in Arabidopsis thaliana, many are still without assigned function. Here, we have screened an insertional mutant library of Arabidopsis pollen‐expressed kinesins for fertility defects. Insertional mutants for three kinesins showed a significant reduction in seed set.
Isabella N. Mendes, Norman R. Groves, Jessica Z. Li, Lily N. Thompson, Brian J. Smith, Aman Y. Husbands, Iris Meier   +6 more
wiley   +1 more source

Nuclear Entanglement: New Insights Into the Role of Cytoskeleton and Nucleoskeleton in Plant Nuclear Function

Cytoskeleton, EarlyView.
ABSTRACT Of the three types of cytoskeleton known in animals—actin, microtubules, and intermediate filaments—only actin and microtubules exist in plants. Both play important roles in cellular shaping, organelle movement, organization of the endomembrane system, and cell signaling.
Norman R. Groves, Katelyn Amstutz, Lily A. Schumacher, Iris Meier   +3 more
wiley   +1 more source

A Myosin XI Tail Domain Homologous to the Yeast Myosin Vacuole-Binding Domain Interacts with Plastids and Stromules in Nicotiana benthamiana [PDF]

Molecular Plant, 2009
The actin cytoskeleton plays a role in mobility of many different organelles in plant cells, including chloroplasts, mitochondria, Golgi, and peroxisomes. While progress has been made in identifying the myosin motors involved in trafficking of various plant organelles, not all of the cargoes mobilized by different members of the myosin XI family have ...
Sattarzadeh, Amir, Krahmer, Johanna, Germain, Arnaud D., Hanson, Maureen R.   +3 more
openaire   +2 more sources

Making Two out of One: Kinesin Motors Driving Plant Cell Division

Cytoskeleton, EarlyView.
ABSTRACT The Kinesin superfamily of microtubule dependent motors is present in all eukaryotes. Not all of the subfamilies are represented in all kingdoms, and the ones that are do not always show conserved functions. Tight control of the cytoskeleton is essential for proper progression and completion of mitosis and cytokinesis, and key functions are ...
Choy Kriechbaum, Sabine Müller
wiley   +1 more source

Myosins XI modulate host cellular responses and penetration resistance to fungal pathogens [PDF]

Proceedings of the National Academy of Sciences, 2014
Significance Remodeling of actin cytoskeleton is thought to contribute to the establishment of effective barriers at the periphery of plant cells against fungal ingress. However, there is little information on the molecular mechanisms that regulate actin remodeling during interactions with invading pathogens.
Long, Yang, Li, Qin, Guosheng, Liu, Valera V, Peremyslov, Valerian V, Dolja, Yangdou, Wei   +5 more
openaire   +2 more sources

Agent‐Based Computational Modeling of the Stochastic Dynamic Behavior of Actin Filaments Recapitulates the Homeostatic Cortical Array in Plant Epidermal Cells

Cytoskeleton, EarlyView.
ABSTRACT The homeostatic cortical actin array in plant cells plays important roles in fundamental processes, including intracellular transport, secretion, cell expansion, and cytoplasmic streaming. In response to diverse chemical and mechanical signals, the cortical array can remodel within minutes to assume new configurations or altered filament ...
June Hyung Kim, Weiwei Zhang, Anjali Iyer‐Pascuzzi, Christopher J. Staiger, Taeyoon Kim   +4 more
wiley   +1 more source