Results 31 to 40 of about 20,285 (238)
This review highlights emerging bioengineering strategies for treating neointimal hyperplasia in the peripheral vasculature, focusing on approaches that promote re‐endothelialization, modulate smooth muscle cell phenotype, reduce inflammation, mitigate oxidative stress, and optimize biomechanical compliance.
Nikita Wilson John+5 more
wiley +1 more source
Mammalian myosin I alpha, I beta, and I gamma: new widely expressed genes of the myosin I family. [PDF]
A polymerase chain reaction strategy was devised to identify new members of the mammalian myosin I family of actin-based motors. Using cellular RNA from mouse granular neurons and PC12 cells, we have cloned and sequenced three 1.2-kb polymerase chain ...
Greene, LA, Joyce, MP, Sherr, EH
core
Force and Motion Generation of Molecular Motors: A Generic Description [PDF]
We review the properties of biological motor proteins which move along linear filaments that are polar and periodic. The physics of the operation of such motors can be described by simple stochastic models which are coupled to a chemical reaction.
A. Ajdari+54 more
core +3 more sources
Engineering Assembloids to Mimic Graft‐Host Skeletal Muscle Interaction
This study develops a graft‐host skeletal muscle assembloid model combining neuromuscular organoids with tissue‐engineered constructs. Pre‐seeding decellularized muscles with myogenic cells enhances cell migration and axon invasion from the organoid. The model exhibits regenerative capacity following acute damage, advancing the understanding of human ...
Lucia Rossi+13 more
wiley +1 more source
The importance of subclasses of chitin synthase enzymes with myosin-like domains for the fitness of fungi [PDF]
Acknowledgements TG and CF are funded by FEDER funds through the Operational Programme Competitiveness Factors – COMPETE and national funds by FCT – Foundation for Science and Technology under the strategic project UID/NEU/04539/2013. C.F. is a recipient
Fernandes, Chantal+2 more
core +1 more source
This review highlights recent progress in piezoelectric materials for regenerative medicine, emphasizing their ability to convert mechanical stimuli into bioelectric signals that promote tissue repair. Key discussions cover the intrinsic piezoelectric properties of biological tissues, co‐stimulation cellular mechanisms for tissue regeneration, and ...
Xinyu Wang+3 more
wiley +1 more source
Thirteen is enough: the myosins of Dictyostelium discoideum and their light chains [PDF]
BACKGROUND: Dictyostelium discoideum is one of the most famous model organisms for studying motile processes like cell movement, organelle transport, cytokinesis, and endocytosis.
Kollmar, Martin
core +3 more sources
Hydrogel‐Mediated Preservation of Live Tumor Explants for Drug Development in Peritoneal Metastases
This study presents a hyaluronan‐based hydrogel platform preserving the native tumor microenvironment (morphology, tissue composition, histology) of patient‐derived explants from peritoneal metastases, enabling clinically relevant drug screening. Hydrogel properties such as stiffness and degradation are crucial for longer‐term histoculture.
Kenny Zhuoran Wu+16 more
wiley +1 more source
Formins Determine the Functional Properties of Actin Filaments in Yeast [PDF]
The actin cytoskeleton executes a broad range of essential functions within a living cell. The dynamic nature of the actin polymer is modulated to facilitate specific cellular processes at discrete locations by actin-binding proteins (ABPs), including ...
Balasubramanian+29 more
core +1 more source
Biomimetic Dynamics of Nanoscale Groove and Ridge Topography for Stem Cell Regulation
Dynamic nanoscale groove‐ridge structures are engineered by flexibly conjugating RGD‐magnetic nanoparticles to nanogroove templates with variable groove widths at the molecular scale. Magnetic control enables cyclic switching between nanoscale groove and ridge states that modulates ligand accessibility of cellular integrins.
Hyunsik Hong+8 more
wiley +1 more source