Results 21 to 30 of about 20,573 (287)
Current Opinion in Structural Biology, 2014 The folding and assembly of myosin motor proteins is essential for most movement processes at the cellular, but also at the organism level. Importantly, myosins, which represent a very diverse family of proteins, require the activity of general and specialized folding factors to develop their full motor function.
Hellerschmied, Doris, Clausen, Tim
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Thirteen is enough: the myosins of
BMC Genomics, 2006 Background Dictyostelium discoideum is one of the most famous model organisms for studying motile processes like cell movement, organelle transport, cytokinesis, and endocytosis.
Kollmar Martin
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Mouse nuclear myosin I knock-out shows interchangeability and redundancy of myosin isoforms in the cell nucleus. [PDF]
, 2013 Nuclear myosin I (NM1) is a nuclear isoform of the well-known "cytoplasmic" Myosin 1c protein (Myo1c). Located on the 11(th) chromosome in mice, NM1 results from an alternative start of transcription of the Myo1c gene adding an extra 16 amino acids at ...
A Bose +59 more
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Frontiers in Physiology, 2018 Elevated levels of the metabolic by-products, including acidosis (i.e., high [H+]) and phosphate (Pi) are putative agents of muscle fatigue; however, the mechanism through which they affect myosin’s function remain unclear. To elucidate these mechanisms,
Mike Woodward, Edward P. Debold
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Thick filament‐associated myosin undergoes frequent replacement at the tip of the thick filament
FEBS Open Bio, 2022 Myosin plays a fundamental role in muscle contraction. Approximately 300 myosins form a bipolar thick filament, in which myosin is continuously replaced by protein turnover.
Emi Ichimura +4 more
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Myosin V-mediated transport of Snc1 and Vps10 toward the trans-Golgi network
European Journal of Cell Biology, 2021 Retrieval of cargo proteins from the endosome towards the trans-Golgi network (TGN) is a crucial intracellular process for cellular homeostasis. Its dysfunction is associated with pathogenesis of Alzheimer and Parkinson's diseases. Myosin family proteins
Vy Nguyen +6 more
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Spatial Organization of the Cytoskeleton enhances Cargo Delivery to Specific Target Areas on the Plasma Membrane of Spherical Cells [PDF]
, 2016 Intracellular transport is vital for the proper functioning and survival of a cell. Cargo (proteins, vesicles, organelles, etc.) is transferred from its place of creation to its target locations via molecular motor assisted transport along cytoskeletal ...
Hafner, Anne E., Rieger, Heiko
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BMC Plant Biology, 2012 Background The positioning and dynamics of vesicles and organelles, and thus the growth of plant cells, is mediated by the acto-myosin system. In Arabidopsis there are 13 class XI myosins which mediate vesicle and organelle transport in different cell ...
Ojangu Eve-Ly +6 more
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Distribution and evolution of stable single α-helices (SAH domains) in myosin motor proteins. [PDF]
PLoS ONE, 2017 Stable single-alpha helices (SAHs) are versatile structural elements in many prokaryotic and eukaryotic proteins acting as semi-flexible linkers and constant force springs.
Dominic Simm, Klas Hatje, Martin Kollmar
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Type-I myosins promote actin polymerization to drive membrane bending in endocytosis
eLife, 2019 Clathrin-mediated endocytosis in budding yeast requires the formation of a dynamic actin network that produces the force to invaginate the plasma membrane against the intracellular turgor pressure.
Hetty E Manenschijn +5 more
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