Results 21 to 30 of about 12,142 (258)
Frontiers in Physiology, 2018 Elevated levels of the metabolic by-products, including acidosis (i.e., high [H+]) and phosphate (Pi) are putative agents of muscle fatigue; however, the mechanism through which they affect myosin’s function remain unclear. To elucidate these mechanisms,
Mike Woodward, Edward P. Debold
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Thick filament‐associated myosin undergoes frequent replacement at the tip of the thick filament
FEBS Open Bio, 2022 Myosin plays a fundamental role in muscle contraction. Approximately 300 myosins form a bipolar thick filament, in which myosin is continuously replaced by protein turnover.
Emi Ichimura +4 more
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Myosin V-mediated transport of Snc1 and Vps10 toward the trans-Golgi network
European Journal of Cell Biology, 2021 Retrieval of cargo proteins from the endosome towards the trans-Golgi network (TGN) is a crucial intracellular process for cellular homeostasis. Its dysfunction is associated with pathogenesis of Alzheimer and Parkinson's diseases. Myosin family proteins
Vy Nguyen +6 more
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Type-I myosins promote actin polymerization to drive membrane bending in endocytosis
eLife, 2019 Clathrin-mediated endocytosis in budding yeast requires the formation of a dynamic actin network that produces the force to invaginate the plasma membrane against the intracellular turgor pressure.
Hetty E Manenschijn +5 more
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BMC Plant Biology, 2012 Background The positioning and dynamics of vesicles and organelles, and thus the growth of plant cells, is mediated by the acto-myosin system. In Arabidopsis there are 13 class XI myosins which mediate vesicle and organelle transport in different cell ...
Ojangu Eve-Ly +6 more
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Distribution and evolution of stable single α-helices (SAH domains) in myosin motor proteins. [PDF]
PLoS ONE, 2017 Stable single-alpha helices (SAHs) are versatile structural elements in many prokaryotic and eukaryotic proteins acting as semi-flexible linkers and constant force springs.
Dominic Simm, Klas Hatje, Martin Kollmar
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Unravelling the molecular basis of the dominant negative effect of myosin XI tails on P-bodies.
PLoS ONE, 2021 The directional movement and positioning of organelles and macromolecules is essential for regulating and maintaining cellular functions in eukaryotic cells.
Lisa Stephan +4 more
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The ancient sarcomeric myosins found in specialized muscles
Skeletal Muscle, 2019 Striated muscles express an array of sarcomeric myosin motors that are tuned to accomplish specific tasks. Each myosin isoform found in muscle fibers confers unique contractile properties to the fiber in order to meet the demands of the muscle.
Lindsey A. Lee +3 more
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Myosin-Powered Membrane Compartment Drives Cytoplasmic Streaming, Cell Expansion and Plant Development. [PDF]
PLoS ONE, 2015 Using genetic approaches, particle image velocimetry and an inert tracer of cytoplasmic streaming, we have made a mechanistic connection between the motor proteins (myosins XI), cargo transported by these motors (distinct endomembrane compartment defined
Valera V Peremyslov +3 more
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