Unravelling the molecular basis of the dominant negative effect of myosin XI tails on P-bodies.
The directional movement and positioning of organelles and macromolecules is essential for regulating and maintaining cellular functions in eukaryotic cells.
Lisa Stephan +4 more
doaj +1 more source
Structures of smooth muscle myosin and heavy meromyosin in the folded, shutdown state [PDF]
Remodelling of the contractile apparatus within smooth muscle cells is an essential process that allows effective contractile activity over a wide range of cell lengths.
Ankrett +60 more
core +1 more source
Teaming up: from motors to people. [PDF]
When I reflect on how I became a cell biologist and why I love being one today, one thing that comes to mind is the many terrific collaborations I have had.
Reck-Peterson, Samara L
core +1 more source
Force and Motion Generation of Molecular Motors: A Generic Description [PDF]
We review the properties of biological motor proteins which move along linear filaments that are polar and periodic. The physics of the operation of such motors can be described by simple stochastic models which are coupled to a chemical reaction.
A. Ajdari +54 more
core +3 more sources
Mammalian Myosin-18A, a Highly Divergent Myosin [PDF]
The Mus musculus myosin-18A gene is expressed as two alternatively spliced isoforms, α and β, with reported roles in Golgi localization, in maintenance of cytoskeleton, and as receptors for immunological surfactant proteins. Both myosin-18A isoforms feature a myosin motor domain, a single predicted IQ motif, and a long coiled-coil reminiscent of myosin-
Stephanie, Guzik-Lendrum +7 more
openaire +2 more sources
The ancient sarcomeric myosins found in specialized muscles
Striated muscles express an array of sarcomeric myosin motors that are tuned to accomplish specific tasks. Each myosin isoform found in muscle fibers confers unique contractile properties to the fiber in order to meet the demands of the muscle.
Lindsey A. Lee +3 more
doaj +1 more source
Myosin-Powered Membrane Compartment Drives Cytoplasmic Streaming, Cell Expansion and Plant Development. [PDF]
Using genetic approaches, particle image velocimetry and an inert tracer of cytoplasmic streaming, we have made a mechanistic connection between the motor proteins (myosins XI), cargo transported by these motors (distinct endomembrane compartment defined
Valera V Peremyslov +3 more
doaj +1 more source
Instabilities and Oscillations in Isotropic Active Gels [PDF]
We present a generic formulation of the continuum elasticity of an isotropic crosslinked active gel. The gel is described by a two-component model consisting of an elastic network coupled frictionally to a permeating fluid.
Ahmadi +47 more
core +4 more sources
The emergence of Pax7-expressing muscle stem cells during vertebrate head muscle development [PDF]
Pax7 expressing muscle stem cells accompany all skeletal muscles in the body and in healthy individuals, efficiently repair muscle after injury. Currently, the in vitro manipulation and culture of these cells is still in its infancy, yet muscle stem ...
Anna eNoble +9 more
core +2 more sources
Does the Actin Network Architecture Leverage Myosin-I Functions?
The actin cytoskeleton plays crucial roles in cell morphogenesis and functions. The main partners of cortical actin are molecular motors of the myosin superfamily.
Julien Pernier, Kristine Schauer
doaj +1 more source

