Results 11 to 20 of about 20,573 (287)
Proceedings of the National Academy of Sciences, 2006 Myosins are a diverse family of actin-based molecular motors that appeared early in eukaryotic evolution. Just how early, and how diverse, has begun to become clear from work that appears in this issue of PNAS (1) and recent work from Nature (2). For most of its existence, the term “myosin” applied only to the actin-activated ATPase that forms the ...
Holly V, Goodson, Scott C, Dawson
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Myosin V and iNOS expression is enhanced in J774 murine macrophages treated with IFN-gamma [PDF]
Brazilian Journal of Medical and Biological Research, 2001 Actin-based motor protein requirements and nitric oxide (NO) production are important features of macrophage activity during phagocytosis or microbicidal processes.
D.S. Reis +3 more
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Non-muscle myosins control the integrity of cortical radial glial endfeet
PLoS Biology, 2023 Radial glial cells, the stem cells of the cerebral cortex, extend a long basal fiber that ends in basal endfeet. A new study in PLOS Biology found that non-muscle myosins control basal endfoot integrity to regulate interneuron organization.
Li Wang, Arnold R. Kriegstein
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The loop2 insertion of type IX myosin acts as an electrostatic actin tether that permits processive movement. [PDF]
PLoS ONE, 2014 Although class IX myosins are single-headed, they demonstrate characteristics of processive movement along actin filaments. Double-headed myosins that move processively along actin filaments achieve this by successive binding of the two heads in a hand ...
Kerstin Elfrink +4 more
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Myosin 1g and 1f: A Prospective Analysis in NK Cell Functions
Frontiers in Immunology, 2021 NK cells are contained in the ILC1 group; they are recognized for their antiviral and antitumor cytotoxic capacity; NK cells also participate in other immune response processes through cytokines secretion.
David Cruz-Zárate +6 more
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Discovery of Viral Myosin Genes With Complex Evolutionary History Within Plankton
Frontiers in Microbiology, 2021 Nucleocytoplasmic large DNA viruses (NCLDVs) infect diverse eukaryotes and form a group of viruses with capsids encapsulating large genomes. Recent studies are increasingly revealing a spectacular array of functions encoded in their genomes, including ...
Soichiro Kijima +6 more
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Control of lipid organization and actin assembly during clathrin-mediated endocytosis by the cytoplasmic tail of the rhomboid protein Rbd2. [PDF]
, 2015 Clathrin-mediated endocytosis (CME) is facilitated by a precisely regulated burst of actin assembly. PtdIns(4,5)P2 is an important signaling lipid with conserved roles in CME and actin assembly regulation. Rhomboid family multipass transmembrane proteins
Cortesio, Christa L +2 more
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Modification of Loop 1 Affects the Nucleotide Binding Properties of Myo1c, the Adaptation Motor in the Inner Ear [PDF]
, 2010 Myo1c is one of eight members of the mammalian myosin I family of actin-associated molecular motors. In stereocilia of the hair cells in the inner ear, Myo1c presumably serves as the adaptation motor, which regulates the opening and closing of ...
Adamek, Nancy +3 more
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Apunts Sports Medicine, 2023 The aim of this study was to determine associations between workload, myosin isoforms, and performance in professional basketball, by following the progress of a professional basketball team over four consecutive seasons.
Mario Guerrero +4 more
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Myosin VIIA is required for aminoglycoside accumulation in cochlear hair cells. [PDF]
, 1997 Myosin VIIA is expressed by sensory hair cells and has a primary structure predicting a role in membrane trafficking and turnover, processes that may underlie the susceptibility of hair cells to aminoglycoside antibiotics. [3H]Gentamicin accumulation and
Brown, S D M +5 more
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