Results 111 to 120 of about 18,015 (263)
The FEBS Journal, EarlyView.Exercise‐related microRNAs cel‐miR‐249‐3p and cel‐miR‐77‐5p in C. elegans regulate lifespan, fitness, mitochondrial morphology and membrane potential. Although lacking direct mammalian orthologs, H2O2‐induced microRNAs mmu‐miR‐181a‐5p and mmu‐miR‐378a‐3p regulate myogenesis, autophagy, mitochondrial content and respiration in murine myoblasts ...
Qin Xia +7 more
wiley +1 more source
, 2023 IntroductionMacrophages play an important role in the innate immunity. While macrophage inflammation is necessary for biological defense, it must be appropriately controlled.
Yuya Nishimura (3473246) +10 more
core +1 more source
The epigenetic landscape of skeletal muscle in response to exercise and aging
The FEBS Journal, EarlyView.Epigenetic mechanisms regulate gene expression in response to exercise and aging, thereby supporting skeletal muscle plasticity. Acute exercise induces chromatin remodeling through histone modifications and DNA methylation, promoting the expression of exercise‐responsive genes.
Sabrina Champsi, David A. Hood
wiley +1 more source
Low-magnitude vertical vibration enhances myotube formation in C2C12 myoblasts
, 2010 Whole body vibration training is widely used in rehabilitation and sports activities to improve muscle strength, balance, and flexibility. However, the molecular mechanisms of vertical vibration (VV) training and their effect on the myogenesis of ...
Chau-Zen Wang +5 more
core +1 more source
The FEBS Journal, EarlyView.Trim32 regulates the transition from proliferation to differentiation in C2C12 cells after myogenic induction. We found that, at the onset of differentiation, Trim32 destabilizes c‐Myc mRNA, promotes cell cycle exit, and enables normal myotube formation.
Lu Xiong +6 more
wiley +1 more source
Toll Like Receptor 4: A Potential Link Between Obesity and Metabolic Diseases
Obesity Reviews, EarlyView.ABSTRACT Epidemiological evidence shows that obesity increases the risk of developing metabolic diseases. Nevertheless, the mechanisms behind this connection remain underappreciated. The substantial impact of these disorders on global health has led to extensive research efforts aimed at identifying the pathophysiological links between them.
Ghadeer Alhamar +4 more
wiley +1 more source
Generation of bovine iPSCs from fetal fibroblasts for in vitro myogenesis and cultured meat
Frontiers in NutritionIntroductionEmerging biotechnologies are increasingly being explored for food production, including the development of cell-cultivated meat. Conventional approaches typically rely on satellite cell (SC) biopsies, which present challenges in scalability ...
Kaiana Recchia +4 more
doaj +1 more source
Frontiers in Sustainable Food Systems, 2019 Ammonia, a byproduct of protein catabolism that is generally regarded as toxic, is processed by the liver for excretion. In diseases resulting in hepatic insufficiency, circulating ammonia levels increase dramatically, ensuing secondary disorders. Sarcopenia, or loss of muscle mass, is commonly associated with hyperammonemia.
Rachel A. Stern +3 more
openaire +2 more sources
Experimental Physiology, EarlyView.Abstract Skeletal muscle adaptation to contractile activity is modulated by redox signalling, primarily through reactive oxygen species (ROS) such as hydrogen peroxide (H2O2). Early research framed ROS as deleterious byproducts of exercise, but subsequent studies have established their roles as signalling molecules involved in mitochondrial biogenesis,
Malcolm J. Jackson
wiley +1 more source
Early lineage segregation of primary myotubes from secondary myotubes and adult muscle stem cells
Nature CommunicationsAbstract Myogenesis in amniotes occurs in two waves. Primary myotubes express slow myosin (often with fast myosin) and likely act as scaffolds for secondary myotubes, which express only fast myosin. The embryonic origins and relationships of these lineages, and their connection to satellite cells, remain unknown.
Toulouse, Gauthier +5 more
openaire +4 more sources