Results 121 to 130 of about 18,015 (263)

In vitro muscle contraction: A technical review on electrical pulse stimulation in C2C12 cells

Experimental Physiology, EarlyView.
Abstract Electrical pulse stimulation (EPS) of skeletal muscle cells is increasingly used to model exercise In vitro. The murine C2C12 myotube system has become a common platform for such studies, yet wide variability in EPS protocols hampers reproducibility and cross‐study comparisons.
Mark R. C. van de Meene, Anita M. van den Hoek, Roeland Hanemaaijer, Lars Verschuren, Jelle C. B. C. de Jong   +4 more
wiley   +1 more source

The effects of TGF-β receptor I inhibitors on myofibroblast differentiation and myotube formation

Frontiers in Cell and Developmental Biology
IntroductionFibrosis frequently occurs in muscle wounds, ultimately leading to suboptimal function. This study investigates the effects of TGF-βRI inhibitors AZ12799734, Galunisertib, and SM16, on myofibroblast differentiation and myotube formation ...
Zhihao Wang, Edwin. M. Ongkosuwito, Johannes W. Von den Hoff, Frank A. D. T. G. Wagener   +3 more
doaj   +1 more source

Stimulation of the AMP/ATP ratio in L6 myotube cells by treatment with acetic acid.

, 2016
Stimulation of the AMP/ATP ratio in L6 myotube cells by treatment with acetic acid.
Yukihiro Yoshimura (332546), Masumi Kimoto (3162330), Hitomi Maruta (3162333), Aya Araki (3162327), Hiromi Yamashita (1270659), Yoshitaka Takahashi (3162336)   +5 more
core   +1 more source

Applying thermal therapy: Comparison of different commercially available heating devices to increase muscle temperature

Experimental Physiology, EarlyView.
Abstract Although various medical devices are available for the purpose of heat therapy, their effect on muscle temperature remains unclear. This study compared the effects of a water‐perfused suit (WPS), short‐wave diathermy (SWD) and hot‐water immersion (HWI) on muscle, core and skin temperatures, along with perceived thermal discomfort.
Nada Nasir, Nathan Townsend, Marco Cardinale, Mariem Labidi, Sebastien Racinais   +4 more
wiley   +1 more source

In vitro supplementation with the porcine plasma product, betaGRO®, stimulates activity of porcine fetal myoblasts and neonatal satellite cells in a divergent manner

Animal, 2018
Two separate experiments were conducted to evaluate the effect of betaGRO® supplementation on in vitro porcine fetal myoblasts (PFM) and porcine satellite cells (PSC) proliferation, fusion and myotube thickness.
M.A. Vaughn, K.J. Phelps, J.M. Gonzalez
doaj   +1 more source

Mitophagy in skeletal muscle: Impact of ageing, exercise and disuse

Experimental Physiology, EarlyView.
Abstract Skeletal muscle plays an important role in whole‐body health, quality of life and regulation of metabolism. The maintenance of a healthy mitochondrial pool is imperative for the preservation of skeletal muscle quality and is mediated through mitochondrial quality control consisting of mitochondrial turnover mediated by a balance between ...
Anastasiya Kuznyetsova, David A. Hood
wiley   +1 more source

SAA causes reduction in myotube widths that can be reversed by blocking TLR2.

, 2016
(A) Control (left panel) and SAA 1μg/ml (right panel) C2C12 myotubes treated with SAA for 48h, immunolabelled with anti-desmin antibody (green). Scale bar = 100μm. (B) Quantification of myotube widths from immunofluorescence images. (C) Myotube widths in
Samantha L. Passey (846720), Gary P. Anderson (330406), Michelle J. Hansen (487070), Ross Vlahos (87783), Steven Bozinovski (330409)   +4 more
core   +1 more source

Intramuscular pathways of maladaptation in overtraining syndrome

The Journal of Physiology, EarlyView.
Abstract figure legend The transition from adaptive overreaching to maladaptive overtraining and mechanisms through which excessive training load can lead to performance decline. Four interconnected pathophysiological domains are highlighted: neural fatigue, involving both central and peripheral components such as altered sensory feedback and reflex ...
Emily Shorter, Oscar Horwath, Sabrina Tzivia Barsky, Ferdinand von Walden, Johanna T. Lanner   +4 more
wiley   +1 more source

The mitochondrial‐targeted antioxidant SkQ1 prevents skeletal muscle mitochondrial‐apoptotic but not necroptotic signalling during ovarian cancer

The Journal of Physiology, EarlyView.
Abstract figure legend An evaluation of the degree to which mitochondrial hydrogen peroxide emission (mH2O2)‐mediated apoptotic and necroptotic signalling contributes to skeletal muscle atrophy in an orthotopic epithelial ovarian cancer (EOC) model. To determine whether attenuating mH2O2 could prevent regulated cell death signalling and mitigate muscle
Shahrzad Khajehzadehshoushtar, Luca J. Delfinis, Fasih A. Rahman, Madison C. Garibotti, Shivam Gandhi, Aditya N. Brahmbhatt, Brooke A. Morris, Bianca Garlisi, Sylvia Lauks, Caroline Aitken, Leslie Ogilvie, Zhu‐Xu Zhang, Jeremy A. Simpson, Joe Quadrilatero, Jim Petrik, Christopher G. R. Perry   +15 more
wiley   +1 more source

The Transmembrane Protein Kon-tiki Couples to Dgrip to Mediate Myotube Targeting in Drosophila

, 2007
SummaryDirected cell migration and target recognition are critical for the development of both the nervous and muscular systems. Molecular mechanisms that control these processes in the nervous system have been intensively studied, whereas those that act
Kalchhauser, Irene, Dickson, Barry J., Schnorrer, Frank   +2 more
core   +1 more source