Results 251 to 260 of about 14,734,718 (295)

ADVERSE REACTIONS TO N-ACETYLCYSTEINE

The Lancet, 1984
1 Clinical details of seven patients who suffered adverse reactions to N-acetylcysteine as Parvolex are documented. 2 Skin testing was carried out to diluted Parvolex, and its individual components N-acetylcysteine and ethylenediaminetetra-acetate, in five reacting patients and five patients who had received Parvolex with no ill ...
D N, Bateman, K W, Woodhouse, M D, Rawlins   +2 more
openaire   +3 more sources

Effectiveness of N-acetylcysteine in autism spectrum disorders: A meta-analysis of randomized controlled trials

Australian and New Zealand journal of psychiatry (Print), 2020
Objective: Currently, pharmaceutical treatment options for autism spectrum disorder are limited. Brain glutaminergic dysregulation is observed in autism spectrum disorder.
Tsung-Min Lee, K. Lee, Chuan-Ya Lee, Hsin-Chien Lee, K. Tam, E. Loh   +5 more
semanticscholar   +1 more source

Development of chitosan-coated liposome for pulmonary delivery of N-acetylcysteine.

International Journal of Biological Macromolecules, 2019
The purpose of the present investigation was to formulate NAC (N-acetylcysteine)-loaded chitosan (CH)-coated liposome aiming at obtaining an effective formulation able to ensure a prolonged and controlled release of NAC to the lung by inhalation.
Hamed Hamedinasab, A. Rezayan, M. Mellat, Mohammad Mashreghi, M. Jaafari   +4 more
semanticscholar   +1 more source

The promise of N-acetylcysteine in neuropsychiatry

Trends in Pharmacological Sciences, 2013
N-Acetylcysteine (NAC) targets a diverse array of factors germane to the pathophysiology of multiple neuropsychiatric disorders including glutamatergic transmission, the antioxidant glutathione, neurotrophins, apoptosis, mitochondrial function, and inflammatory pathways.
Michael, Berk, Gin S, Malhi, Laura J, Gray, Olivia M, Dean   +3 more
openaire   +2 more sources

Pharmacokinetics of N-acetylcysteine in man

European Journal of Clinical Pharmacology, 1986
N-Acetylcysteine was given intravenously and as three fast dissolving and one slow-release formulation, on separate occasions, as a single dose of 600 mg to 10 fasting (5 men and 5 women) healthy volunteers. Blood and urine were sampled for the following 12 h. Renal clearance constituted around 30% of total body clearance, which was 0.21 l/h/kg. Volume
L, Borgström, B, Kågedal, O, Paulsen
openaire   +2 more sources

What is the most appropriate dose of N-acetylcysteine after massive acetaminophen overdose?

Clinical toxicology, 2019
While the traditional intravenous N-acetylcysteine (NAC) dosing regimen works well for the vast majority of acetaminophen overdoses, there may be cases of massive overdose where additional NAC may be necessary. Recent evidence suggests that patients with
R. Hendrickson
semanticscholar   +1 more source

Intratympanic application of poloxamer 407 hydrogels results in sustained N-acetylcysteine delivery to the inner ear.

European journal of pharmaceutics and biopharmaceutics, 2020
N-acetylcysteine is a thiol-containing antioxidant, which has shown otoprotective effects in in-vitro as well as in-vivo models of cisplatin induced hearing loss.
Julia Clara Gausterer, Nodir Saidov, N. Ahmadi, Chengjing Zhu, M. Wirth, G. Reznicek, C. Arnoldner, F. Gabor, C. Honeder   +8 more
semanticscholar   +1 more source

N-acetylcysteine as a treatment for amatoxin poisoning: a systematic review

Clinical toxicology, 2020
Introduction: Amatoxin leads to the majority of deaths by mushroom poisoning around the world. Amatoxin causes gastrointestinal disturbances and multiple organ dysfunction, including liver and renal failure.
Jiaming Liu, Yang Chen, Yanxia Gao, J. Walline, Xin Lu, Shiyuan Yu, Lina Zhao, Zengzheng Ge, Yi Li   +8 more
semanticscholar   +1 more source

N-Acetylcysteine in Chronic Blepharitis

Cornea, 2002
To investigate the effects of N-acetylcysteine (NAC) in chronic posterior blepharitis.This was a prospective randomized, controlled study that included 79 eyes of 40 patients with chronic posterior blepharitis. Routine ophthalmologic examination, Schirmer-1 test, fluorescein break-up time (FBUT), and mucous fern tests were carried out during the first ...
Elvan, Yalçin, Feyza, Altin, Feriha, Cinhüseyinoglue, M Okan, Arslan   +3 more
openaire   +2 more sources

Hyperthyroidism and N-Acetylcysteine

Journal of the American Medical Directors Association, 2021
Seema, Rao, S, Rao
openaire   +2 more sources