Molecular Characterisation of Bacteriophage K Towards Applications for the Biocontrol of Pathogenic Staphylococci [PDF]
, 2006 End of project reportThe aim of this work was to characterise staphylococcal bacteriophage (a bacterial virus) and to assess their potential as therapeutic agents against pathogenic strains of Staphylococcus aureus, particularly mastitis-causing strains.
Coffey, Aidan +5 more
core
LysJEP8: A promising novel endolysin for combating multidrug‐resistant Gram‐negative bacteria
Microbial Biotechnology, Volume 17, Issue 6, June 2024.Antimicrobial resistance (AMR), driven by antibiotic misuse, is a global crisis, especially with multidrug‐resistant Gram‐negative bacteria. LysJEP8, derived from Escherichia phage JEP8, shows promising antimicrobial activity against these pathogens, offering a potential solution to combat AMR.
Jose Vicente Carratalá +3 more
wiley +1 more source
MsrR contributes to cell surface characteristics and virulence in Staphylococcus aureus [PDF]
, 2017 MsrR, a factor contributing to methicillin resistance in Staphylococcus aureus, belongs to the LytR-CpsA-Psr family of cell envelope-associated proteins.
Berger-Bächi, Brigitte +7 more
core
The proteome of the heterocyst cell wall in Anabaena sp. PCC 7120 [PDF]
, 2007 Anabaena sp. PCC 7120 is a filamentous cyanobacterium that serves as a model to analyze prokaryotic cell differentiation, evolutionary development of plastids, and the regulation of nitrogen fixation.
Berg, Matthias +8 more
core +1 more source
Comparative genetics of Enterococcus faecalis intestinal tissue isolates before and after surgery in a rat model of colon anastomosis. [PDF]
, 2020 We have recently demonstrated that collagenolytic Enterococcus faecalis plays a key and causative role in the pathogenesis of anastomotic leak, an uncommon but potentially lethal complication characterized by disruption of the intestinal wound following ...
Alverdy, John C +8 more
core +1 more source
Metagenomic analysis of hot spring soil for mining a novel thermostable enzybiotic
Applied Microbiology and BiotechnologyThe misuse and overuse of antibiotics have contributed to a rapid emergence of antibiotic-resistant bacterial pathogens. This global health threat underlines the urgent need for innovative and novel antimicrobials.
Panagiota D Pantiora +3 more
semanticscholar +1 more source
Efficient Recovery of Complete Gut Viral Genomes by Combined Short‐ and Long‐Read Sequencing
Advanced Science, Volume 11, Issue 13, April 3, 2024.The CHGV, a human gut virome database, comprises 21,499 non‐redundant phage genomes obtaine through viral‐like particle enrichment and combined short‐ and long‐read sequencing. The long‐reads facilitate the identification of more complete viral genomes and surprisingly favor lowly abundant ones.
Jingchao Chen +12 more
wiley +1 more source
LytR-CpsA-Psr proteins in Staphylococcus aureus display partial functional redundancy and the deletion of all three severely impairs septum placement and cell separation [PDF]
, 2017 Staphylococcus aureus contains three members of the LytR-CpsA-Psr (LCP) family of membrane proteins: MsrR, SA0908 and SA2103. The characterization of single-, double- and triple-deletion mutants revealed distinct phenotypes for each of the three proteins.
Berger-Bächi, Brigitte +8 more
core
Biomolecular Corona of Gold Nanoparticles: The Urgent Need for Strong Roots to Grow Strong Branches
Small, Volume 20, Issue 15, April 11, 2024.This review presents a critical analysis of the current methodologies to decipher bio‐nano interactions by analyzing the biomolecular corona using gold nanoparticles as a case study. The study aims for a collective effort of the nano‐community through standardization of methodologies (for synthesis, characterization, and omics), data sharing, and ...
Luca Boselli +4 more
wiley +1 more source
DUF3380 domain from a Salmonella phage endolysin shows potent N -acetylmuramidase activity [PDF]
, 2016 Bacteriophage-encoded endolysins are highly diverse enzymes that cleave the bacterial peptidoglycan layer. Current research focuses on their potential applications in medicine, in food conservation, and as biotechnological tools.
Hans Gerstmans +6 more
core +1 more source