Abstract The emergence of antimicrobial‐resistant foodborne pathogens poses a continuous health risk and economic burden as they can easily spread through contaminated food. Therefore, the demand for new antimicrobial agents to address this problem is steadily increasing.
Dahee Choi, Sangryeol Ryu, Minsuk Kong
wiley +1 more source
Improved accuracy of cell surface shaving proteomics in Staphylococcus aureus using a false-positive control [PDF]
Proteolytic treatment of intact bacterial cells is an ideal means for identifying surface-exposed peptide epitopes and has potential for the discovery of novel vaccine targets.
Cordwell, Stuart J +2 more
core +1 more source
Insights Into Phylogeny, Diversity and Functional Potential of Poseidoniales Viruses
Our spatio‐temporal metagenomic study of a subtropical estuary successfully identified viruses and their potential hosts. Viral contigs were detected using a consensus approach comprising geNOMAD and VirSorter2. Through virus‐host predictions, we were able to identify, characterise and propose magroviruses and non‐magroviruses associated with ...
Apoorva Prabhu +4 more
wiley +1 more source
Skl, a novel choline‐binding N‐acetylmuramoyl‐
The skl gene from Streptococcus mitis SK137 encodes a peptidoglycan hydrolase (Skl) that has been purified and biochemically characterized. Analysis of the degradation products obtained by digestion of pneumococcal cell walls with Skl revealed that this enzyme is an N‐acetylmuramoyl‐l‐alanine amidase (EC 3.5.1.28), showing optimum activity at 30 °C and
Llull, Daniel +2 more
openaire +2 more sources
FtsZ-independent septal recruitment and function of cell wall remodelling enzymes in chlamydial pathogens. [PDF]
The nature and assembly of the chlamydial division septum is poorly defined due to the paucity of a detectable peptidoglycan (PG)-based cell wall, the inhibition of constriction by penicillin and the presence of coding sequences for cell wall precursor ...
Frandi, A. +4 more
core +2 more sources
Isolation, Genome Annotation, Characterisation, and Therapeutic Application of the vB_EfaS_SZ1 Enterococcus Phage. This study isolated and identified a novel lytic phage that infects HLGR Enterococcus faecalis. vB_EfaS_SZ1 exhibited advantageous traits, including enhanced stability and efficacy.
Fatma Al‐zahraa A. Yehia +5 more
wiley +1 more source
Listeria bacteriophage peptidoglycan hydrolases feature high thermoresistance and reveal increased activity after divalent metal cation substitution [PDF]
The ability of the bacteriophage-encoded peptidoglycan hydrolases (endolysins) to destroy Gram-positive bacteria from without makes these enzymes promising antimicrobials.
Loessner, Martin +2 more
core
Characterization of Streptococcus gordonii prophage PH15: complete genome sequence and functional analysis of phage-encoded integrase and endolysin [PDF]
Streptococcus gordonii OMZ1039, isolated from supragingival dental plaque, was found to harbour a prophage, PH15, whose excision could be induced by mitomycin treatment. Phage PH15 belongs to the Siphoviridae.
van der Ploeg, J R
core +1 more source
Bacteriophages (phages) have emerged as promising agents for combating bacterial pathogens, including nontyphoidal Salmonella enterica (S. enterica), the most common foodborne pathogen worldwide. The emergence of antimicrobial‐resistant (AMR) S. enterica poses a severe healthcare issue.
Chuan-Wei Tung +6 more
wiley +1 more source
Cloning of bacteriophage lysins and evaluation of their antibacterial activity against Enterococcus faecalis [PDF]
Enterococci are the causative agents of several serious infections. In addition, antibiotic- resistant enterococci are becoming increasingly prevalent due to the extensive use of antibiotics in the community and in hospitals.
STRITT, K.
core

