Characterization of a novel N-acetylneuraminic acid lyase favoring industrial N-acetylneuraminic acid synthesis process [PDF]
Scientific Reports, 2015 AbstractN-Acetylneuraminic acid lyase (NAL, E.C. number 4.1.3.3) is a Class I aldolase that catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (Neu5Ac) from pyruvate and N-acetyl-D-mannosamine (ManNAc). Due to the high Neu5Ac cleavage activity in most isozyme forms, the enzyme catalyzes the rate-limiting step of two biocatalytic ...
Wenyan Ji +7 more
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Correction: Corrigendum: Characterization of a novel N-acetylneuraminic acid lyase favoring industrial N-acetylneuraminic acid synthesis process [PDF]
Scientific Reports, 2017 Scientific Reports 5: Article number: 09341; published online: 23 March 2015; updated: 28 April 2017 The original version of this article contained an error in testing the kinetic parameters of CgNal towards pyruvate, in which the concentration of ManNAc (50 mM) was not in excess.
Wujin Sun +7 more
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Synthesis of partially O-acetylated N-acetylneuraminic acid using regioselective silyl exchange technology. [PDF]
Org Lett, 2014 Postglycosylation acetylation of sialic acid imparts unique roles to sialoglycoconjugates in mammalian immune response making structural and functional understanding of these analogues important.
Gervay-Hague, Jacquelyn, Park, Simon S
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A novel variant in CMAH is associated with blood type AB in Ragdoll cats [PDF]
, 2016 Citation: Gandolfi, B., Grahn, R. A., Gustafson, N. A., Proverbio, D., Spada, E., Adhikari, B., . . . Helps, C. R. (2016). A novel variant in CMAH is associated with blood type AB in Ragdoll cats. Plos One, 11(5).
Adhikari, B. +9 more
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Ferrets exclusively synthesize Neu5Ac and express naturally humanized influenza A virus receptors [PDF]
, 2014 Mammals express the sialic acids N-acetylneuraminic acid (Neu5Ac) and N-glycolylneuraminic acid (Neu5Gc) on cell surfaces, where they act as receptors for pathogens, including influenza A virus (IAV). Neu5Gc is synthesized from Neu5Ac by the enzyme
Böhm, Raphael +14 more
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Neuraminidase Activity in \u3cem\u3eDiplococcus pneumoniae\u3c/em\u3e [PDF]
, 1966 Kelly, R. T. (Marquette University School of Medicine, Milwaukee, Wis.), D. Greiff, and S. Farmer. Neuraminidase activity in Diplococcus pneumoniae. J. Bacteriol. 91:601–603.
ADA G. L. +9 more
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An orthologue of bacteroides fragilis NanH is the principal sialidase in tannerella forsythia [PDF]
, 2009 Sialidase activity is a putative virulence factor of the anaerobic periodontal pathogen Tannerella forsythia, but it is uncertain which genes encode this activity.
Booth, V. +4 more
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Molecular imprinting and grafting of n-acetylneuraminic acid in synthetic polymers for virus targeting [PDF]
, 2021 In this work, the synthesis of Molecularly Imprinted Polymers (MIPs) was executed using different solvents, N,N-dimethylformamide (DMF), Acetonitrile (ACN), and a mixture of both reagents, two different monomers, 4-vinylpiridine (4VP) and 4 ...
Noronha, Verônica Teixeira
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Occurrence of a new hematoside in the kidney of guinea pig [PDF]
, 1983 We have isolated a new hematoside from guinea pig kidney. Like the usual hematoside (II3NeuAc-LacCer), isolated from human erythrocytes, this new hematoside contained glucose, galactose, and N-acetylneuraminic acid in an equimolar proportion.
Hirabayashi, Yoshia +2 more
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Streptococcus pneumoniae NanC. Structural insights into the specificity and mechanism of a sialidase that produces a sialidase inhibitor [PDF]
, 2015 This work was supported by the Biotechnology and Biological Sciences Research Council (UK) and the Medical Research Council (UK).Streptococcus pneumoniae is an important human pathogen that causes a range of disease states.
Lukacik, Petra +5 more
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