A Novel Variant in CMAH Is Associated with Blood Type AB in Ragdoll Cats. [PDF]
PLoS ONE, 2016 The enzyme cytidine monophospho-N-acetylneuraminic acid hydroxylase is associated with the production of sialic acids on cat red blood cells. The cat has one major blood group with three serotypes; the most common blood type A being dominant to type B. A
Barbara Gandolfi +9 more
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Molecular characterization of cytidine monophospho-N-acetylneuraminic acid hydroxylase (CMAH) associated with the erythrocyte antigens in dogs [PDF]
Canine Genetics and Epidemiology, 2019 Background N-glycolylneuraminic acid (Neu5Gc) is synthesized from its precursor N-acetylneuraminic acid (Neu5Ac) by cytidine-5′-monophospho-N acetylneuraminic acid hydroxylase (CMAH), which is encoded by the CMAH gene.
Yumiko Uno +3 more
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Presence of N-acetylneuraminic acid in the lung during postnatal development [PDF]
European Journal of Histochemistry, 2020 Sialic acids, particularly N-acetylneuraminic acid (Neu5Ac), are present as terminal components of rich and complex oligosaccharide chains, which are termed glycans, and are exhibited on the cell surfaces, especially on epithelial cells.
Maria de Fátima Martins +3 more
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N-Acetylneuraminic Acid Analogues
Journal of Biological Chemistry, 1971 Abstract The action of N-acetylneuraminic acid aldolase on 7- and 8-carbon analogues of N-acetylneuraminic acid has been studied. The 8-carbon analogue was slowly and reversibly cleaved by the aldolase to yield 2-acetamido-2-deoxy-d-lyxose and pyruvic acid. The 7-carbon analogue was not cleaved by the enzyme.
Maitree Suttajit +2 more
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One-pot biosynthesis of N-acetylneuraminic acid from chitin via combination of chitin-degrading enzymes, N-acetylglucosamine-2-epimerase, and N-neuraminic acid aldolase [PDF]
Frontiers in Microbiology, 2023 N-acetylneuraminic acid (Neu5Ac) possesses the ability to promote mental health and enhance immunity and is widely used in both medicine and food fields as a supplement.
Quanzhen Liu +6 more
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Distinguishing N-acetylneuraminic acid linkage isomers on glycopeptides by ion mobility-mass spectrometry. [PDF]
Chemical Communications, 2016 Differentiating the structure of isobaric glycopeptides represents a major challenge for mass spectrometry-based characterisation techniques. Here we show that the regiochemistry of the most common N-acetylneuraminic acid linkages of N-glycans can be ...
H. Hinneburg +11 more
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Corrigendum: Characterization of a novel N-acetylneuraminic acid lyase favoring industrial N-acetylneuraminic acid synthesis process. [PDF]
Sci Rep, 2017 Scientific Reports 5: Article number: 09341; published online: 23 March 2015; updated: 28 April 2017 The original version of this article contained an error in testing the kinetic parameters of CgNal towards pyruvate, in which the concentration of ManNAc (50 mM) was not in excess.
Ji W +7 more
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Methods for the quantitative estimation of N-acetylneuraminic acid and their application to hydrolysates of sialomucoids [PDF]
Biochemical Journal, 1961 David Aminoff
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The fate of orally administered sialic acid: First insights from patients with N-acetylneuraminic acid synthase deficiency and control subjects [PDF]
Molecular Genetics and Metabolism Reports, 2021 Background: In NANS deficiency, biallelic mutations in the N-acetylneuraminic acid synthase (NANS) gene impair the endogenous synthesis of sialic acid (N-acetylneuraminic acid) leading to accumulation of the precursor, N-acetyl mannosamine (ManNAc), and ...
Christel Tran +13 more
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High fat diet-induced inflammation and oxidative stress are attenuated by N-acetylneuraminic acid in rats. [PDF]
J Biomed Sci, 2015 Serum sialic acid levels are positively correlated with coronary artery disease and inflammation. Although sialic acid is a non-specific marker, it is considered sensitive likely due to its influence in sialylation of glycoprotein structures all over the
Yida Z +5 more
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