Presence of N-acetylneuraminic acid in the lung during postnatal development [PDF]
European Journal of Histochemistry, 2020 Sialic acids, particularly N-acetylneuraminic acid (Neu5Ac), are present as terminal components of rich and complex oligosaccharide chains, which are termed glycans, and are exhibited on the cell surfaces, especially on epithelial cells.
Maria de Fátima Martins +3 more
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One-pot biosynthesis of N-acetylneuraminic acid from chitin via combination of chitin-degrading enzymes, N-acetylglucosamine-2-epimerase, and N-neuraminic acid aldolase [PDF]
Frontiers in Microbiology, 2023 N-acetylneuraminic acid (Neu5Ac) possesses the ability to promote mental health and enhance immunity and is widely used in both medicine and food fields as a supplement.
Quanzhen Liu +6 more
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COLOMINIC ACID, A POLYMER OF N-ACETYLNEURAMINIC ACID [PDF]
The Journal of Experimental Medicine, 1958 All acidic carbohydrate has been isolated from the culture medium of the enteric microorganism E. coli K235 L+O. This substance has been named colominic acid. N-acetylneuraminic acid, which has been isolated from the hydrolysate of colominic acid, is believed to be the monomer unit from which colominic acid is constituted.
G. T. Barry
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Corrigendum: Characterization of a novel N-acetylneuraminic acid lyase favoring industrial N-acetylneuraminic acid synthesis process. [PDF]
Sci Rep, 2017 Scientific Reports 5: Article number: 09341; published online: 23 March 2015; updated: 28 April 2017 The original version of this article contained an error in testing the kinetic parameters of CgNal towards pyruvate, in which the concentration of ManNAc (50 mM) was not in excess.
Ji W +7 more
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N-acetylneuraminic acid: A scrutinizing tool in oral squamous cell carcinoma diagnosis [PDF]
Dental Research Journal, 2017 Background: Oral cancer has one of the highest mortality rate among other malignancies. An attempt has been made to assess the genetic expression of a cell surface glycoprotein component - sialic acid released by the malignant cells which will reflect on
Suganya Rajaram +4 more
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The fate of orally administered sialic acid: First insights from patients with N-acetylneuraminic acid synthase deficiency and control subjects [PDF]
Molecular Genetics and Metabolism Reports, 2021 Background: In NANS deficiency, biallelic mutations in the N-acetylneuraminic acid synthase (NANS) gene impair the endogenous synthesis of sialic acid (N-acetylneuraminic acid) leading to accumulation of the precursor, N-acetyl mannosamine (ManNAc), and ...
Christel Tran +13 more
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Serum N-Acetylneuraminic Acid Is Associated with Atrial Fibrillation and Left Atrial Enlargement [PDF]
Cardiology Research and Practice, 2020 Purpose. Recent studies have indicated that N-acetylneuraminic acid (Neu5Ac) plays a key role in severe coronary artery diseases, involving RhoA signaling pathway activation, which is critically involved in cardiac fibrosis.
Wei Hu +11 more
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High fat diet-induced inflammation and oxidative stress are attenuated by N-acetylneuraminic acid in rats. [PDF]
J Biomed Sci, 2015 Serum sialic acid levels are positively correlated with coronary artery disease and inflammation. Although sialic acid is a non-specific marker, it is considered sensitive likely due to its influence in sialylation of glycoprotein structures all over the
Yida Z +5 more
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N-Acetylneuraminic acid attenuates hypercoagulation on high fat diet-induced hyperlipidemic rats [PDF]
Food & Nutrition Research, 2015 Background and objective: N-Acetylneuraminic acid (Neu5Ac), a type of sialic acid, has close links with cholesterol metabolism and is often used as a biomarker in evaluating the risk of cardiovascular diseases.
Zhang Yida +6 more
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Hydroxylation of N-acetylneuraminic Acid Influences the in vivo Tropism of N-linked Sialic Acid-Binding Adeno-Associated Viruses AAV1, AAV5, and AAV6 [PDF]
Frontiers in Medicine, 2021 Adeno-associated virus (AAV) vectors are promising candidates for gene therapy. However, a number of recent preclinical large animal studies failed to translate into the clinic. This illustrates the formidable challenge of choosing the animal models that
Estrella Lopez-Gordo +6 more
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