N-アセチルノイラミン酸によるCandida albicans形態変化の制御について [PDF]
Candida albicans is a dimorphic fungus and generally grows in hyphal form in RPMI1640 medium. However, addition of N-acetylneuraminic acid inhibited the hyphal growth. The expression of CGR1 mRNA in C.
Ayako OGASAWARA+11 more
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Conservation of structure and mechanism in primary and secondary transporters exemplified by SiaP, a sialic acid binding virulence factor from Haemophilus influenzae [PDF]
Extracytoplasmic solute receptors (ESRs) are important components of solute uptake systems in bacteria, having been studied extensively as parts of ATP binding cassette transporters.
Kelly, D.J.+7 more
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Marine Bacterial Sialyltransferases [PDF]
Sialyltransferases transfer N-acetylneuraminic acid (Neu5Ac) from the common donor substrate of these enzymes, cytidine 5′-monophospho-N-acetylneuraminic acid (CMP-Neu5Ac), to acceptor substrates.
Angata+72 more
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Human-like NSG Mouse Glycoproteins Sialylation Pattern Changes the Phenotype of Human Lymphocytes and Sensitivity to HIV-1 Infection [PDF]
BACKGROUND: The use of immunodeficient mice transplanted with human hematopoietic stem cells is an accepted approach to study human-specific infectious diseases such as HIV-1 and to investigate multiple aspects of human immune system development. However,
Branch-Woods, Amanda+11 more
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Plasma Sialic Acid Levels in Normal Beagles [PDF]
Glycoproteins are found in cell membraines, plasma and in various secretions. Many plasma proteins have carbohydrates covalently bound to them. Carbohydrate unites will containe hexoses, N-acetylglucoseamine, Nacetylgalactoseamine, fucose and sialic acid
Engen, R. L., Fuller, William
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ROLE OF XENOSIALIZATION IN THE PATHOGENESIS OF COLITIS IN THE CANINE MODEL: POSSIBLE POSITIVE EFFECTS OF NEW PROBIOTICS BLENDS [PDF]
Inflammatory bowel disease (IBD) is a heterogeneous state of chronic intestinal inflammation with no exact known cause. In dogs, IBD is expressed histologically with lymphoplasmacytic inflammation (LPL) of gastrointestinal tract.
Alessandra, Gavazza+8 more
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Possible Role of Dietary N-glycolyneuraminic Acid and Dysbiosis in Canine Enteropathy Pathogenesis [PDF]
N-glycolylneuraminic acid (Neu5Gc) is synthesized from its N-acetyl precursor (Neu5Ac) by cytidine-50- monophospho-N acetylneuraminic acid hydroxylase (CMAH). Absent in humans and ferrets, it is polymorphic in dogs.
Alessandra Gavazza+10 more
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Precursor ion scanning for detection and structural characterization of heterogeneous glycopeptide mixtures [PDF]
The structure of N-linked glycans is determined by a complex, anabolic, intracellular pathway but the exact role of individual glycans is not always clear.
Deery, M J+3 more
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Expression of sialic acids and other nonulosonic acids in Leptospira [PDF]
BackgroundSialic acids are negatively charged nine carbon backbone sugars expressed on mammalian cell surfaces. Sialic acids are part of a larger family of nonulosonic acid (NulO) molecules that includes pseudaminic and legionaminic acids.
Lewis, Amanda L+3 more
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In vitro and in vivo modification of Neisseria gonorrhoeae lipooligosaccharide epitope structure by sialylation. [PDF]
After growth of gonococci in the presence of cytidine monophospho-N-acetyl-neuraminic acid (CMP-NANA), their 4.5-kD lipooligosaccharide (LOS) component was increased by approximately 400 daltons, whereas the LOS of strains lacking the 4.5-kD component ...
Apicella, MA+9 more
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