Results 31 to 40 of about 836,707 (292)

Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression

open access: yesHepatology, EarlyView., 2022
Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández   +18 more
wiley   +1 more source

Synthesis of partially O-acetylated N-acetylneuraminic acid using regioselective silyl exchange technology. [PDF]

open access: yesOrg Lett, 2014
Postglycosylation acetylation of sialic acid imparts unique roles to sialoglycoconjugates in mammalian immune response making structural and functional understanding of these analogues important.
Park SS, Gervay-Hague J.
europepmc   +4 more sources

Analysis of the interaction between N-acetylneuraminic acid and disaccharides on silica surface

open access: yesХімія, фізика та технологія поверхні, 2020
Nanocomposites based on biomolecules and highly dispersed silica are quite promising for use in many fields of biotechnology. There are many methods of obtaining such materials, in particular, adsorption from liquid or gas phases.
L. M. Ushakova   +4 more
doaj   +1 more source

Improved N‐acetylneuraminic acid bioproduction by optimizing pathway for reducing intermediate accumulation

open access: yesFood Bioengineering, 2022
N‐acetylneuraminic acid (NeuAc), which has been widely used as a nutraceutical and pharmaceutical intermediate, plays an important role in improving brain development and cognition while enhancing immunity. Bacillus subtilis, generally regarded as a food‐
Haoyu Guo   +6 more
doaj   +1 more source

Function and Expression of an N -Acetylneuraminic Acid-Inducible Outer Membrane Channel in Escherichia coli [PDF]

open access: greenJournal of Bacteriology, 2005
Guy Condemine   +3 more
openalex   +2 more sources

Development of N‐acetylneuraminic acid responsive biosensors based on the transcriptional regulator NanR

open access: greenBiotechnology and Bioengineering, 2018
Gert Peters   +6 more
openalex   +3 more sources

Comparison of sialic acid content in bovine and buffalo milk and meat

open access: yesRevista Científica, 2023
Animal-origin food, such as meat and milk, are important sources of sialic acids (SIAs) with relevant implications for human health. Two significant SIAs in mammals are N-acetyl-neuraminic acid (Neu5Ac) and N- glycolylneuraminic acid (Neu-5Gc).
Michela Contò   +2 more
doaj   +1 more source

Generation of an NANS homozygous knockout human induced pluripotent stem cell line by the insertion of GFP-P2A-Puro via CRISPR/Cas9 editing

open access: yesStem Cell Research, 2020
N-acetylneuraminic acid synthase (NANS), the gene encoding the synthase for N-acetylneuraminic acid (NeuNAc; sialic acid), is closely associated with infantile-onset severe developmental delay and skeletal dysplasia.
Qian Bu   +10 more
doaj   +1 more source

An Overview of the Importance and Value of Porcine Species in Sialic Acid Research

open access: yesBiology, 2022
Humans frequently interact with pigs, whose meat is also one of the primary sources of animal protein. They are one of the main species at the center of sialic acid (Sia) research.
Oluwamayowa Joshua Ogun   +2 more
doaj   +1 more source

Characterization of recombinant human lactoferrin N-glycans expressed in the milk of transgenic cows. [PDF]

open access: yes, 2017
Lactoferrin (LF) is one of the most abundant bioactive glycoproteins in human milk. Glycans attached through N-glycosidic bonds may contribute to Lactoferrin functional activities. In contrast, LF is present in trace amounts in bovine milk.
Barile, Daniela   +5 more
core   +6 more sources

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