Results 31 to 40 of about 809,751 (208)

Dataset on inflammatory proteins expressions and sialic acid levels in apolipoprotein E-deficient mice with administration of N-acetylneuraminic acid and/or quercetin

Data in Brief, 2016
The data presented in this article describe an effect of N-acetylneuraminic acid and/or quercetin on the inflammatory proteins expressions (TNF-α, ICAM-1, VCAM-1 and MOMA-2) and the N-acetylneuraminic acid (NANA) levels of apolipoprotein E-deficient mice
Rongrong Dong, Fahui Li, Shucun Qin, Yi Wang, Yanhong Si, Xuelian Xu, Hua Tian, Lei Zhai, Guangjie Zhang, Yongjun Li, Yawei Zhou, Ying Zhang, Nan Zhang, Shoudong Guo   +13 more
doaj   +1 more source

Estimation of Salivary and Serum Total Sialic Acid Levels in Periodontal Health and Disease [PDF]

Journal of Clinical and Diagnostic Research, 2014
Background: Chronic gingivitis and periodontitis are inflammatory diseases. An important function of host sialic acid is to regulate innate immunity. The aim of the study was to assess the concentration of Total sialic acid (TSA) in saliva and serum ...
SUREKHA R RATHOD, FAROOQUE KHAN, ABHAY P KOLTE, MADHUR GUPTA   +3 more
doaj   +1 more source

Synthesis of Sulfo-Sialic Acid Analogues: Potent Neuraminidase Inhibitors in Regards to Anomeric Functionality

Scientific Reports, 2017
The design, synthesis and application of N-acetylneuraminic acid-derived compounds bearing anomeric sulfo functional groups are described. These novel compounds, which we refer to as sulfo-sialic acid analogues, include 2-decarboxy-2-deoxy-2-sulfo-N ...
Christopher J. Vavricka, Chiaki Muto, Tomohisa Hasunuma, Yoshinobu Kimura, Michihiro Araki, Yan Wu, George F. Gao, Hiroshi Ohrui, Minoru Izumi, Hiromasa Kiyota   +9 more
doaj   +1 more source

Enhancement of the Yu and Ledeen gas-liquid chromatographic method for sialic acid estimation: use of methane chemical ionization mass fragmentography

Journal of Lipid Research, 1980
The sialic acid present in erythrocyte ghosts was estimated by methane chemical ionization mass fragmentography of the trimethylsilyl methyl glycosides. The internal standard was 3,4,6-tris-trimethylsilyl-alpha-phenyl-2-deoxy-2-acetamide-D-glucosaminide,
J Ashraf, D A Butterfield, J Järnefelt, R A Laine   +3 more
doaj   +1 more source

Molecular Structural Analysis of Porcine CMAH–Native Ligand Complex and High Throughput Virtual Screening to Identify Novel Inhibitors

Pathogens, 2023
Porcine meat is the most consumed red meat worldwide. Pigs are also vital tools in biological and medical research. However, xenoreactivity between porcine’s N-glycolylneuraminic acid (Neu5Gc) and human anti-Neu5Gc antibodies poses a significant ...
Oluwamayowa Joshua Ogun, Georg Thaller, Doreen Becker   +2 more
doaj   +1 more source

Marine Bacterial Sialyltransferases

Marine Drugs, 2010
Sialyltransferases transfer N-acetylneuraminic acid (Neu5Ac) from the common donor substrate of these enzymes, cytidine 5’-monophospho-N-acetylneuraminic acid (CMP-Neu5Ac), to acceptor substrates.
Takeshi Yamamoto
doaj   +1 more source

Human species-specific loss of CMP-N-acetylneuraminic acid hydroxylase enhances atherosclerosis via intrinsic and extrinsic mechanisms

Proceedings of the National Academy of Sciences of the United States of America, 2019
Significance Cardiovascular disease (CVD) events like heart attacks and strokes due to atherosclerotic narrowing of arteries are the commonest cause of worldwide deaths, but many first-time events occur in individuals without known risk factors.
K. Kawanishi, Chirag Dhar, Raymond Do, N. Varki, P. Gordts, A. Varki   +5 more
semanticscholar   +1 more source

Preparation, characterisation and antibacterial activity evaluation of N-acetylneuraminic acid-crosslinked chitosan hydrogels

Polymer Testing, 2022
In this study, CS-NeuAc hydrogel was prepared from chitosan (CS) and N-acetylneuraminic acid (NeuAc) using cyclic freeze/thaw under 1-ethyl-3-(3-dimethylaminopropyl)-carbodiiminde/N-hydroxysuccinimide catalysis. Fourier transformed infrared spectroscopy,
Yuanfei Ge, Xiangsong Chen, Xiangqin Wang, Lixia Yuan, Jinyong Wu, Jianming Yao   +5 more
doaj   +1 more source

Sialic Acid (N-Acetylneuraminic Acid) in Human Serum

Clinical Chemistry, 1964
Abstract A simple spectrophotometric method is described for the sialic acids which utilizes the reaction with resorcinol and extraction with butyl acetate-n-butanol as a solvent. Normal values for adults, utilizing N-acetylneuraminic acid as a standard, were found to be 60 ± 10.4 mg./100 ml. Values for newborn babies averaged 40.4 ± 5.7.
J A, CABEZAS, J V, PORTO
openaire   +2 more sources

Characterization of gangliosides by direct inlet chemical ionization mass spectrometry.

Journal of Lipid Research, 1984
Permethylated derivatives of N-acetylneuraminic acid-containing GM3, N-glycolylneuraminic acid-containing GM3, GD1a, and GD1b, were analyzed by direct inlet ammonia chemical ionization (CI) mass spectrometry.
T Argia, R K Yu, T Miyatake
doaj   +1 more source