Results 141 to 150 of about 13,626,059 (252)

Multivalent RNA‐Cleaving Agents on a Cubic Octameric Silsesquioxane Core

Chemistry – A European Journal, EarlyView.
RNA‐cleaving agents on a cubic octameric silsesquioxane core were synthesized and characterized. Several catalytic systems of these structures were screened using hexaribonucleotide models. The best systems were then further used to study their catalytic efficiency in cleaving a HER2 mRNA model sequence. The induced cleavage sites were also determined.
Hanni Haapsaari, Iris Tuomi, Pasi Virta
wiley   +1 more source

Interstitial fluid N-glycans serve as a proxy for serum biomarker discovery in a pilot study. [PDF]

Sci Rep
Saldova R, Gaymore TK, Walsh C, Zavala E, Mendes PM.   +4 more
europepmc   +1 more source

Membrane lipid metabolism as a regulatory frontier in neural crest biology: Roles for sphingolipids, cholesterol, and lipid rafts

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are multipotent, migratory stem‐like cells essential for vertebrate development that contribute broadly to many tissues including the craniofacial skeleton, peripheral nervous system, and pigment‐producing cells. Their development progresses through phases of induction, specification, delamination, migration, and ...
Allison E. Mancini, Mallorie P. Jenne, Michael L. Piacentino   +2 more
wiley   +1 more source

N-Glycans modulate tilting of HIV-1 envelope glycoprotein. [PDF]

Nat Commun
Shehata M, Casalino L, Duquette M, Chen S, Flaherty A, Waller PM, Villa E, Amaro RE.   +7 more
europepmc   +1 more source

Chelation‐Assisted Metal‐Catalyzed Ligation and Cleavage Reactions for Chemical Biology

European Journal of Organic Chemistry, EarlyView.
Chelation‐assisted transition metal catalysis has emerged as a promising complement to bioorthogonal click chemistry for studying biological processes. By pre‐organizing catalytic metal centers, designed coordinating substrates enhance reactivity and biocompatibility, enabling site‐selective ligation and decaging reactions in complex biological media ...
Emilie Plantiveau, Maxime Riberaud, Frédéric Taran, Antoine Sallustrau   +3 more
wiley   +1 more source

The role of N-glycans and their processing in ER-to-lysosome-associated degradation of disease-causing mutant Neuroserpin. [PDF]

Autophagy Rep
Hoefner C, Fregno I, Molinari M.
europepmc   +1 more source

Electroclinical phenotypes—genetic characterization of developmental and epileptic encephalopathies in a cohort study

Epileptic Disorders, EarlyView.
Abstract Objective Developmental and epileptic encephalopathies (DEEs) are characterized by refractory seizures and frequently recurring epileptic activity with neurodevelopmental delay or regression that usually begin in early life. We aimed to define the relationship between electroclinical features and etiology, as well as the genotype–phenotype ...
Burcu Yaman, Fulya Kurekci, Sinan Akbas, Ceyda Oney, Mehmet Akif Kilic, Hulya Maras Genc, Ayca Dilruba Aslanger, Edibe Pembegul Yildiz   +7 more
wiley   +1 more source

Conformational Preferences for N-Glycans at the Surface of CEACAM1-Ig1. [PDF]

ACS Chem Biol
Eletsky A, Huang C, Miao Y, Moremen KW, Morris LC, Prestegard JH.   +5 more
europepmc   +1 more source

Controlling the source of mannose in N-glycans

, 2012
Controlling the source of mannose in N ...
David Scott (13093551), Marie-Estelle Losfeld (19562281), Mie Ichikawa (727707), Hudson H Freeze (19562284)   +3 more
core  

Stage‐Dependent Metabolic Reprogramming Drives a Self‐Organizing Microbial Network During Shanxi Aged Vinegar

Food Bioengineering, EarlyView.
Metabolic shifts from growth to stress adaptation in Shanxi aged vinegar fermentation link flavor maturation and microbial cooperation, and Lactobacillus and Acetobacter form a self‐organizing metabolic network through division of labor. ABSTRACT Acetic acid fermentation (AAF) is a vital stage in the production of Shanxi aged vinegar (SAV), during ...
Yanfang Wu, Jing Liu, Dantong Liu, Menglei Xia, Jia Song, Yu Zheng, Min Wang   +6 more
wiley   +1 more source