Frontiers in Immunology, 2020 Toll-like receptor 8 (TLR-8) plays a role in the pathogenesis of autoimmune disorders and associated gastrointestinal symptoms that reduce quality of life of patients. Dietary interventions are becoming more accepted as mean to manage onset, progression,
Susana Figueroa-Lozano +6 more
doaj +1 more source
Glycosylation pattern of brush border-associated glycoproteins in enterocyte-like cells: involvement of complex-type N-glycans in apical trafficking [PDF]
, 2009 We have previously reported that galectin-4, a tandem repeat-type galectin, regulates the raft-dependent delivery of glycoproteins to the apical brush border membrane of enterocyte-like HT-29 cells.
Huet, Guillemette +8 more
core +1 more source
TbGT8 is a bifunctional glycosyltransferase that elaborates N-linked glycans on a protein phosphatase AcP115 and a GPI-anchor modifying glycan in Trypanosoma brucei [PDF]
, 2014 The procyclic form of Trypanosoma brucei expresses procyclin surface glycoproteins with unusual glycosylphosphatidylinositol-anchor side chain structures that contain branched N-acetyllactosamine and lacto-N-biose units.
Hashida, Kazunori +7 more
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Engineering, 2023 Aberrant glycosylation is considered to be a hallmark of colorectal cancer (CRC), as demonstrated by various studies. While the N-glycosylation of cell lines and serum has been widely examined, the analysis of cancer-associated N-glycans from tissues has
Di Wang +4 more
doaj +1 more source
From structural to functional glycomics: core substitutions as molecular switches for shape and lectin affinity of N-glycans [PDF]
, 2009 Glycan epitopes of cellular glycoconjugates act as versatile biochemical signals (sugar coding). Here, we test the hypothesis that the common N-glycan modifications by core fucosylation and introduction of the bisecting N-acetylglucosamine moiety have ...
André, Sabine +4 more
core +1 more source
Structural feature of N-glycans of bamboo shoot glycoproteins: useful source of plant antigenic N-glycans [PDF]
, 2017 An effective method to prepare plant complex type (PCT) N-glycans in large amounts has been required to evaluate their immunological activity. In this study, we found that glycoproteins in bamboo shoots predominantly carry PCT N-glycans including the ...
Megumi, Maeda +3 more
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PLoS ONE, 2015 The HIV envelope glycoprotein gp120 contains nine disulphide bridges and is highly glycosylated, carrying on average 24 N-linked glycans. Using a probability calculation, we here demonstrate that there is a co-localization of disulphide bridges and N ...
Leen Mathys, Jan Balzarini
doaj +1 more source
Identification and functional characterization of a highly divergent N-acetylglucosaminyltransferase I (TbGnTI) in Trypanosoma brucei [PDF]
, 2014 Trypanosoma brucei expresses a diverse repertoire of N-glycans, ranging from oligomannose and paucimannose structures to exceptionally large complex N-glycans.
Damerow, Manuela +5 more
core +1 more source
Change in N-Glycosylation of Plasma Proteins in Japanese Semisupercentenarians. [PDF]
PLoS ONE, 2015 An N-glycomic analysis of plasma proteins was performed in Japanese semisupercentenarians (SSCs) (mean 106.7 years), aged controls (mean 71.6 years), and young controls (mean 30.2 years) by liquid chromatography/mass spectrometry (LC/MS) using a ...
Yuri Miura +10 more
doaj +1 more source
Approaching the secrets of N-glycosylation in Aspergillus fumigatus [PDF]
, 2010 The mannosyltransferase Och1 is the key enzyme for synthesis of elaborated protein N-glycans in yeast. In filamentous fungi genes implicated in outer chain formation are present, but their function is unclear.
Engel Jakob +25 more
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