Results 111 to 120 of about 15,525,833 (178)

N-glycolylneuraminic acid conjugates: implications of their absence in mammalian biochemistry.

Indian journal of biochemistry & biophysics, 2012
N-glycolylneuraminic acid (Neu5Gc) is one of the two most common forms of sialic acids present in glycoproteins and glycolipids of mammalian tissues. It is synthesized from the most ubiquitous sialic acid, N-acetylneuraminic acid (Neu5Ac) in a hydroxylation reaction catalysed by the enzyme Neu5Ac hydroxylase.
Daniel W, Mwangi, Devi D, Bansal
openaire   +1 more source

Analysis on the terahertz spectral characteristics of two types of sialic acids in solid state and aqueous solution

Scientific Reports
In this study, N-acetylneuraminic acid (Neu5Ac) and N-glycolylneuraminic acid (Neu5Gc) were chosen as representative sialic acids to study their terahertz (THz) spectral characteristics in solid and aqueous states.
Zhuang Peng, Yang Gao, Xinrui Zhang, Huiyu Yang, Bo Su, Kai Li, Cunlin Zhang   +6 more
doaj   +1 more source

Assessment of Sialic Acid Content in Dairy Products from Buffalo’s and Goat’s Milk Compared to Cow’s Milk

Dairy
Sialic acids (SIAs) are bioactive compounds present in glycoproteins and glycolipids, playing key roles in human physiology. N-acetylneuraminic acid (Neu5Ac), the only sialic acid synthesized by humans, contributes to neurodevelopment and immune function,
Simona Rinaldi, Michela Contò, Carlo Boselli, Giuliano Palocci, Angelo Citro, Sebastiana Failla   +5 more
doaj   +1 more source

Evidence of free radical participation in N-glycolylneuraminic acid generation in liver of chicken treated with gallotannic acid

, 2004
20-28The occurrence of N-glycolylneuraminic acid (Neu5Gc) in cancerous tissue and inflammatory diseases, conditions associated with increased oxidative stress suggests the participation of reactive oxygen radicals in Neu5Gc generation, where an oxygen ...
Bansal, Devi D, Mwangi, Danny W
core  

Possible Role of Dietary N-glycolyneuraminic Acid and Dysbiosis in Canine Enteropathy Pathogenesis [PDF]

N-glycolylneuraminic acid (Neu5Gc) is synthesized from its N-acetyl precursor (Neu5Ac) by cytidine-50- monophospho-N acetylneuraminic acid hydroxylase (CMAH). Absent in humans and ferrets, it is polymorphic in dogs.
Alessandra Gavazza, Matteo Cerquetella, Ilaria Patuzzi, Lucia Biagini, Sinem Gultekin, Barbara Simionati, Livio Galosi, Fiorella Carnevali, Daniela Oliviero, Giacomo Rossi, Sara Ricci   +10 more
core   +1 more source

Sensitive and specific detection of the non-human sialic Acid N-glycolylneuraminic acid in human tissues and biotherapeutic products. PLoS One 4: e4241

, 2009
Background: Humans are genetically defective in synthesizing the common mammalian sialic acid N-glycolylneuraminic acid (Neu5Gc), but can metabolically incorporate it from dietary sources (particularly red meat and milk) into glycoproteins and ...
Nancy Hurtado-Ziola, Ajit Varki, Vered Padler-Karavani, Hai Yu, Sandra L Diaz, Xi Chen, Els C M Brinkman-Van Der Linden, Darius Ghaderi, Nissi M Varki   +8 more
core  

N-Glycolylneuraminic acid conjugates: Implications of their absence in mammalian biochemistry

, 2003
217-225N-glycolylneuraminic acid (Neu5Gc) is one of the two most common forms of sialic acids present in glycoproteins and glycolipids of mammalian tissues.
Mwangi, Daniel W, Bansal, Devi D
core  

Loss of N-glycolylneuraminic acid in human evolution. Implications for sialic acid recognition by siglecs.

The Journal of biological chemistry, 2000
The common sialic acids of mammalian cells are N-acetylneuraminic acid (Neu5Ac) and N-glycolylneuraminic acid (Neu5Gc). Humans are an exception, because of a mutation in CMP-sialic acid hydroxylase, which occurred after our common ancestor with great apes.
E C, Brinkman-Van der Linden, E R, Sjoberg, L R, Juneja, P R, Crocker, N, Varki, A, Varki   +5 more
openaire   +1 more source

Serological Assessment of Alpha Galactosidase, N-Glycolylneuraminic Acid, and Histopathological Observations in Xenograft Recipients. [PDF]

Cureus
Ramesh B, Ramanan S, Srimurugan B, Fakoya AO.   +3 more
europepmc   +1 more source

Subcellular-distribution of Glycolyltransferases in Rodent Liver and Their Significance in Special Reference To the Synthesis of N-glycolylneuraminic Acid

, 1992
The enzymic synthesis, transfer, and utilization of glycolyl-CoA (i.e. 2-hydroxyacetyl-CoA) have been studied in rat and mouse livers. On the one hand, these tissues contain the enzyme activities allowing the synthesis of glycolyl-CoA from fatty acids ...
Hénichart, Jean-Pierre, Vamecq, J., Mestdagh, N., Poupaert, Jacques   +3 more
core