N-Methyl-3,4-methylenedioxyamphetamine-induced hepatotoxicity in rats: Oxidative stress after acute and chronic administration [PDF]
Background. The underlying mechanisms of N-Methyl-3,4-methylenedioxyamphetamine-MDMA-induced hepatotoxicity are still unknown. The aim of this study was to evaluate hepatic oxido-reductive status in the rats liver after the single and repeated ...
Ninković Milica +4 more
doaj +4 more sources
MDMA (N-methyl-3,4-methylenedioxyamphetamine) and its stereoisomers: Similarities and differences in behavioral effects in an automated activity apparatus in mice [PDF]
Racemic MDMA (0.3-30 mg/kg), S(+)-MDMA (0.3-30 mg/kg), R(-)-MDMA (0.3-50 mg/kg) and saline vehicle (10 ml/kg) were comprehensively evaluated in fully automated and computer-integrated activity chambers, which were designed for mice, and provided a detailed analysis of the frequency, location, and/or duration of 18 different activities.
Richard, Young, Richard A, Glennon
europepmc +4 more sources
From Efficacy to Effectiveness: Evaluating Psychedelic Randomized Controlled Trials for Trustworthy Evidence‐Based Policy and Practice [PDF]
The recent review of a new drug application for MDMA‐assisted therapy for posttraumatic stress disorder by the United States' Food and Drug Administration (FDA) highlighted epistemological and methodological challenges for evidence assessments.
Eduardo Ekman Schenberg
doaj +3 more sources
The Effects of Folic Acid on Testicular Histology, Sperm Quality, and Spermatogenesis Indices Following 3,4-Methylenedioxymethamphetamine Exposure in Adult Male Rats [PDF]
Background: There is an increasing concern over acute exposure of amphetamine and its derivative such as3,4-methylenedioxymethamphetamine (MDMA) on male reproductive toxicity. Supplementary vitamins canreduce the oxidative stresses and repair the damages
Iman Rad +6 more
doaj +3 more sources
Ecstasy tablets intoxication with lethal autcome [PDF]
Background. Ecstasy, 3,4-methylenedioxymethamphetamine (MDMA), is a synthetic compound increasingly popular as a recreational drug. Tablets known as ecstasy contain MDMA, but may also contain caffeine, ephedrine, paramethoxyamphetamine, 3,4 ...
Đorđević Snežana +1 more
doaj +3 more sources
USO DE 3,4-METILENODIOXMETANFETAMINA NO TRATAMENTO DE TRANSTORNO DE ESTRESSE PÓS-TRAUMÁTICO [PDF]
Introdução: O transtorno de estresse pós-traumático (TEPT) se caracteriza pela persistência de reações intensas a lembranças de um evento traumático. Nos últimos anos, houve uma série de estudos neurocientíficos e clínicos examinando o potencial de 3,4 ...
Estela Oliveira Rodrigues +9 more
semanticscholar +3 more sources
Polyacrylonitrile Nanofiber-Based Quartz Crystal Microbalance for Sensitive Detection of Safrole
Safrole is the main precursor for producing the amphetamine-type stimulant (ATS) drug, N-methyl-3,4-methylenedioxyamphetamine (MDMA), also known as ecstasy.
Aditya Rianjanu +6 more
doaj +2 more sources
Recurrent Syncope following Substance Abuse; a Case Report [PDF]
Drug abuse is considered as the most common poisoning in the world. Stimulants agent especially amphetamines and methamphetamines are among important abused substances.
Forod Salehi +3 more
doaj +4 more sources
Entactogens: How the Name for a Novel Class of Psychoactive Agents Originated
At first glance, it appears there is little difference between the molecular structures of methylenedioxymethamphetamine (MDMA), which has an N-methyl attached to its amino group, and methylenedioxyamphetamine (MDA), a primary amine that is recognized to
David E. Nichols
doaj +1 more source
Efeitos terapêuticos dos psicodélicos em doenças psiquiátricas: uma revisão integrativa
Objetivo: analisar a capacidade de atuação das drogas psicodélicas no sistema nervoso central, auxiliando no tratamento de doenças psiquiátricas. Materiais e Métodos: trata-se de revisão integrativa feita a partir de buscas nas bases de dados PubMed e ...
Karen Gonçalves Santos Ribeiro +4 more
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