Results 121 to 130 of about 4,267 (193)

Abundant mRNA m1A modification in dinoflagellates: a new layer of gene regulation

EMBO Reports
Dinoflagellates, a class of unicellular eukaryotic phytoplankton, exhibit minimal transcriptional regulation, representing a unique model for exploring gene expression.
Chongping Li, Ying Li, Jia Guo, Yuci Wang, Xiaoyan Shi, Yangyi Zhang, Nan Liang, Honghui Ma, Jie Yuan, Jiawei Xu, Hao Chen   +10 more
doaj   +1 more source

Detection of: N 6-methyladenosine based on the methyl-sensitivity of MazF RNA endonuclease [PDF]

, 2017
We found that Escherichia coli MazF toxin, an ACA-sequence-specific endoribonuclease, was sensitive to N⁶-methyladenosine (m6A), representing the first m6A-sensitive RNA cleavage enzyme.
Futaki, Shiroh, Imanishi, Miki, Suda, Akiyo, Tsuji, Shogo   +3 more
core   +1 more source

The regulatory role of N1-methyladenosine in tRNA in the development of urothelial carcinoma of the bladder

, 2023
Urothelial carcinoma of the bladder (BLCA) is a disease of high occurrence globally. A high recurrence frequency often necessitates lifelong control schemes of invasive examinations and harsh treatment, reducing the life quality of patients. Several RNA-modifying proteins have been associated with BLCA, and a link between transfer RNA (tRNA ...
openaire   +2 more sources

The functions and mechanisms of RNA modification in prostate: Current status and future perspectives

Frontiers in Genetics
The increasing incidence and mortality of prostate cancer worldwide significantly impact the life span of male patients, emphasizing the urgency of understanding its pathogenic mechanism and associated molecular changes that regulate tumor progression ...
Zhijin Zhang, Zhijin Zhang, Ji Liu, Ji Liu, Yang Wu, Zhuoran Gu, Zhuoran Gu, Libin Zou, Libin Zou, Yingdi Liu, Jiang Geng, Jiang Geng, Shiyu Mao, Shiyu Mao, Ming Luo, Ming Luo, Changcheng Guo, Changcheng Guo, Wentao Zhang, Wentao Zhang, Xudong Yao, Xudong Yao   +21 more
doaj   +1 more source

Recent Findings in N6-Methyladenosine Modification and Significance in Pancreatic Cancer [PDF]

Hara T., Meng S., Arao Y., et al. Recent Findings in N6-Methyladenosine Modification and Significance in Pancreatic Cancer. Cancer Medicine 14, e70934 (2025); https://doi.org/10.1002/cam4.70934.Background: RNA modifications are widely detected in cells ...
Arao, Yasuko, Hara, Tomoaki, Inoue, Kana, Ishii, Hideshi, Kitagawa, Toru, Meng, Sikun, Ofusa, Ken, Rennie, Sarah, Saito, Yoshiko   +8 more
core   +1 more source

N1-methyladenosine formation, gene regulation, biological functions, and clinical relevance

Molecular Therapy, 2023
Weidong Xiong, Yongchao Zhao, Zilun Wei, Chaofu Li, Ranzun Zhao, Junbo Ge, Bei Shi   +6 more
openaire   +1 more source

Advances in research on RNA methylation and cancer radiotherapy resistance

Frontiers in Oncology
RNA methylation is a type of reversible chemical modification in epitranscriptomics that influences gene expression by dynamically regulating RNA functions.
Hui Liu, Hui Luo, Ming Jin, Zhen Zheng, Yang Xi, Kaitai Liu   +5 more
doaj   +1 more source

Studies on N1-Methyladenosine Modification of rRNA in Multicellular Organisms

Studies on N1-Methyladenosine Modification of rRNA in Multicellular Organisms
2017 【要旨】
openaire   +1 more source

Methyladenine as a regulator of biomolecular condensation [PDF]

Ribonucleotide modifications modulate RNA structure and stability, thereby influencing RNA turnover and a wide range of cellular functions. Recent studies have revealed that specific RNA modifications can also affect the formation, composition, and ...
Gian G. Tartaglia, R. Martin Vabulas, Roberto Arsiè   +2 more
core   +1 more source

The role of RNA 2′-O-methylation in prostate cancer [PDF]

2′-O-methylation (Nm) represents a pervasive RNA modification occurring in multiple RNA species, including messenger RNA (mRNA), ribosomal RNA (rRNA), transfer RNA (tRNA), microRNA (miRNA), and PIWI-interacting RNA (piRNA).
Wang, Rui, Wu, Siqi, yi, yang
core   +2 more sources