Results 101 to 110 of about 237 (128)
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Sensors and Actuators B: Chemical, 2022
Abstract Specific and accurate determination of N1-Methyladenosine (m1A) is of critical significance to better understand its biological functions. Precise quantification of low level of RNA modification against a high background of homologous normal RNA still remains a big challenge.
Yuanyuan Sun +3 more
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Abstract Specific and accurate determination of N1-Methyladenosine (m1A) is of critical significance to better understand its biological functions. Precise quantification of low level of RNA modification against a high background of homologous normal RNA still remains a big challenge.
Yuanyuan Sun +3 more
openaire +1 more source
Small Molecule‐Inducible and Photoactivatable Cellular RNA N1‐Methyladenosine Editing
Angewandte ChemieAbstractN1‐methyladenosine (m1A) modification is one of the most prevalent epigenetic modifications on RNA. Given the vital role of m1A modification in RNA processing such as splicing, stability and translation, developing a precise and controllable m1A editing tool is pivotal for in‐depth investigating the biological functions of m1A.
Guoyou Xie +12 more
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Method for isolation of 2′-O-methylribonucleosides and N1-methyladenosine from ribonucleic acid
Biochimica et Biophysica Acta, 1963Abstract N1-methyladenosine and the 2′-O-methyl derivatives of adenosine, uridine, guanosine, and cytidine have been isolated from yeast soluble RNA. A nucleoside mixture obtained by enzymic hydrolysis of the RNA was resolved by means of chromatography on partition columns into major fractions.
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Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie, 1981
We describe the selective analysis of N-methylated ribonucleosides, i.e., N1-methyl adenosine (m1Ado) and N7-methyl guanosine (m7Guo) in the presence of other nucleosides in urine. m1Ado as well as m7Guo were characterized by use of chromatographic techniques including substance specific chemical reactions.
E, Schlimme, K S, Boos, M, Weise
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We describe the selective analysis of N-methylated ribonucleosides, i.e., N1-methyl adenosine (m1Ado) and N7-methyl guanosine (m7Guo) in the presence of other nucleosides in urine. m1Ado as well as m7Guo were characterized by use of chromatographic techniques including substance specific chemical reactions.
E, Schlimme, K S, Boos, M, Weise
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ACS Chemical Biology
tRNA modifications help maintain tRNA structure and facilitate translation and stress response. Found in all three kingdoms of life, m1A tRNA modification occurs in the T loop of many tRNAs, stabilizes tertiary tRNA structure, and impacts translation.
Marcus Foo +6 more
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tRNA modifications help maintain tRNA structure and facilitate translation and stress response. Found in all three kingdoms of life, m1A tRNA modification occurs in the T loop of many tRNAs, stabilizes tertiary tRNA structure, and impacts translation.
Marcus Foo +6 more
openaire +2 more sources
Methods
With the recent advanced direct RNA sequencing technique that proposed by the Oxford Nanopore Technologies, RNA modifications can be detected and profiled in a simple and straightforward manner. Majority nanopore-based modification studies were devoted to those popular types such as m6A and pseudouridine.
Shenglun, Chen, Jia, Meng, Yuxin, Zhang
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With the recent advanced direct RNA sequencing technique that proposed by the Oxford Nanopore Technologies, RNA modifications can be detected and profiled in a simple and straightforward manner. Majority nanopore-based modification studies were devoted to those popular types such as m6A and pseudouridine.
Shenglun, Chen, Jia, Meng, Yuxin, Zhang
openaire +2 more sources
A methionine-Mettl3-N-methyladenosine axis promotes polycystic kidney disease
Cell Metabolism, 2021Mohammed Kanchwala +2 more
exaly
N6-methyladenosine-mediated gene regulation and therapeutic implications
Trends in Molecular Medicine, 2023Jianhua Yu, Ping Yi, Yujiao Liu
exaly
Identification and characterization of N6‐methyladenosine modification of circRNAs in glioblastoma
Journal of Cellular and Molecular Medicine, 2021Fulin Liu, Hong Wang, Xiuchao Geng
exaly
Emerging Roles of N6-Methyladenosine Modification in Neurodevelopment and Neurodegeneration
Cells, 2021Xuekun Li, Liqi Shu, Xuejun Cheng
exaly