Results 81 to 90 of about 237 (128)

The regulatory role of N1-methyladenosine in tRNA in the development of urothelial carcinoma of the bladder

, 2023
Urothelial carcinoma of the bladder (BLCA) is a disease of high occurrence globally. A high recurrence frequency often necessitates lifelong control schemes of invasive examinations and harsh treatment, reducing the life quality of patients. Several RNA-modifying proteins have been associated with BLCA, and a link between transfer RNA (tRNA ...
openaire   +2 more sources

Clinician’s Guide to Epitranscriptomics: An Example of N1-Methyladenosine (m1A) RNA Modification and Cancer

Life
Epitranscriptomics is the study of modifications of RNA molecules by small molecular residues, such as the methyl (-CH3) group. These modifications are inheritable and reversible. A specific group of enzymes called “writers” introduces the change to the RNA; “erasers” delete it, while “readers” stimulate a downstream effect.
Jelačić, Josipa, Ozretić, Petar
openaire   +1 more source

Abundant mRNA m1A modification in dinoflagellates: a new layer of gene regulation

EMBO Reports
Dinoflagellates, a class of unicellular eukaryotic phytoplankton, exhibit minimal transcriptional regulation, representing a unique model for exploring gene expression.
Chongping Li, Ying Li, Jia Guo, Yuci Wang, Xiaoyan Shi, Yangyi Zhang, Nan Liang, Honghui Ma, Jie Yuan, Jiawei Xu, Hao Chen   +10 more
doaj   +1 more source

Alkbh3 functions with Nupr1 in a n1-methyladenosine dependent manner.

We measured total in conjunction with N1-methyladenosine marks in human cells lacking Alkbh3 to understand function of the m1A mark in transcriptional biology and the immune system. We demonstrate here interaction of Alkbh3 with Nupr1.     
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Studies on N1-Methyladenosine Modification of rRNA in Multicellular Organisms

Studies on N1-Methyladenosine Modification of rRNA in Multicellular Organisms
2017 【要旨】
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The functions and mechanisms of RNA modification in prostate: Current status and future perspectives

Frontiers in Genetics
The increasing incidence and mortality of prostate cancer worldwide significantly impact the life span of male patients, emphasizing the urgency of understanding its pathogenic mechanism and associated molecular changes that regulate tumor progression ...
Zhijin Zhang, Zhijin Zhang, Ji Liu, Ji Liu, Yang Wu, Zhuoran Gu, Zhuoran Gu, Libin Zou, Libin Zou, Yingdi Liu, Jiang Geng, Jiang Geng, Shiyu Mao, Shiyu Mao, Ming Luo, Ming Luo, Changcheng Guo, Changcheng Guo, Wentao Zhang, Wentao Zhang, Xudong Yao, Xudong Yao   +21 more
doaj   +1 more source

N1-methyladenosine formation, gene regulation, biological functions, and clinical relevance

Molecular Therapy, 2023
Weidong Xiong, Yongchao Zhao, Zilun Wei, Chaofu Li, Ranzun Zhao, Junbo Ge, Bei Shi   +6 more
openaire   +1 more source

Advances in research on RNA methylation and cancer radiotherapy resistance

Frontiers in Oncology
RNA methylation is a type of reversible chemical modification in epitranscriptomics that influences gene expression by dynamically regulating RNA functions.
Hui Liu, Hui Luo, Ming Jin, Zhen Zheng, Yang Xi, Kaitai Liu   +5 more
doaj   +1 more source

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

RNA modifications in peripheral blood are associated with acute coronary syndrome

Journal of Molecular and Cellular Cardiology Plus
Acute coronary syndromes (ACS) trigger inflammatory and immune reactions, yet whether this response is associated with changes in RNA modifications remains poorly understood.
Miron Sopic, Victoria Stopa, Jelena Munjas, Aleksandar Davidović, Luka Vukmirović, Dane Cvijanović, Marko Milanov, Fabio Martelli, François Bernardin, Nathalie Michelle Legrave, Yvan Devaux   +10 more
doaj   +1 more source