Results 151 to 160 of about 46,645 (191)

Engineering Bisubstrates to Target m6Am RNA Methyltransferases: Synthesis and Computational Studies

Chemistry – A European Journal, Volume 32, Issue 24, 23 June 2026.
Use of the convertible nucleoside approach to synthesize m6Am RNA methyltransferase bisubstrates. This methodology allows for the introduction of modifications on the SAM analog moiety and the RNA substrate part, including the introduction of a cap analog by click chemistry.
Yoann Colas, Laurent Le Corre, Mélanie Ethève‐Quelquejeu, Emmanuelle Braud   +3 more
wiley   +1 more source

Science of omics: a molecular space odyssey

Experimental Physiology, EarlyView.
Salomé Coppens, Christophe Hirtz, Margaux Vignon, Damian M. Bailey   +3 more
wiley   +1 more source

Disease‐Associated Remodeling of m6A RNA Methylation in Human Interstitial Cells From Fibro‐Calcific Aortic Valves

The FASEB Journal, Volume 40, Issue 11, 15 June 2026.
Direct RNA sequencing of primary human valvular interstitial cells (VICs) from non‐calcified control and fibro‐calcific aortic stenosis (AS) valves reveals disease‐associated remodeling of m6A RNA methylation. AS‐derived VICs show an overall increase in detected m6A sites, together with transcript‐specific hyper‐ and hypo‐methylation patterns ...
Vincenza Valerio, Omar Molla, Ilaria Massaiu, Gloria Garoffolo, Veronika A. Myasoedova, Mattia Chiesa, Paolo Poggio   +6 more
wiley   +1 more source

Comprehensive analysis of m6A RNA methylation regulators for prognostic risk stratification and immune microenvironment characterization in colorectal cancer

Open Medicine
Despite mounting evidence of N6-methyladenosine (m6A) dysregulation in colorectal cancer (CRC), comprehensive prognostic association analysis remains limited.
Kong Fei-Fei, Feng Jiawei, Liu Jing-Ya, Gan Wen-Yuan, Zhu Ling-Jun   +4 more
doaj   +1 more source

Regulatory mechanisms and therapeutic potential of N6-methyladenosine modification in retinal diseases (Review). [PDF]

Mol Med Rep
Zhang W, Chen J, Zhong J.
europepmc   +1 more source

FUS is an N1- and N6-methyladenosine-binding protein. [PDF]

Nucleic Acids Res
Liang X, Zhao T, Dai X, Sun Y, Yuan J, Afzalpurkar S, Duong C, Yu A, Tang F, He X, Liu X, Chen X, Cao Z, Wang Y.   +13 more
europepmc   +1 more source

A bibliometric analysis of advances in N6‑methyladenosine research in colorectal cancer. [PDF]

Discov Oncol
Zhao L, Sun Y, Li J, Yang W, Wang Z, Yu B, Du L.   +6 more
europepmc   +1 more source

Epitranscriptomic Stability-Variable Extents of N1-Methyladenosine to N6-Methyladenosine Conversion Under Different Experimental Conditions. [PDF]

Biomolecules
Shnaider FM, Kanan H, Patel S, Chiu NHL.
europepmc   +1 more source

Profiles and roles of N6-methyladenosine modification in bovine oocyte maturation. [PDF]

BMC Genomics
Han T, Wang Z, Gan X, Yang Z, Wang W, Hu K, Zhu R, Li Y, Zhang Y, Cao Z.   +9 more
europepmc   +1 more source

N6-methyladenosine modification in the context of viral infection: from molecular mechanism to therapeutic potential. [PDF]

Virus Res
Wu X, Deng Z, Li Y, Shi C.
europepmc   +1 more source